SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q15486

- GUSP1_HUMAN

UniProt

Q15486 - GUSP1_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Putative inactive beta-glucuronidase-like protein SMA3

Gene
GUSBP1, SMA3
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein uncertaini

Functioni

GO - Molecular functioni

  1. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. nervous system development Source: ProtInc
  3. skeletal system development Source: ProtInc
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Putative inactive beta-glucuronidase-like protein SMA3
Gene namesi
Name:GUSBP1
Synonyms:SMA3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:13670. GUSBP1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 140140Putative inactive beta-glucuronidase-like protein SMA3PRO_0000057682Add
BLAST

Proteomic databases

PaxDbiQ15486.

Expressioni

Tissue specificityi

Ubiquitous.

Gene expression databases

GenevestigatoriQ15486.

Interactioni

Protein-protein interaction databases

IntActiQ15486. 7 interactions.
MINTiMINT-1373382.

Structurei

3D structure databases

ProteinModelPortaliQ15486.
SMRiQ15486. Positions 18-91.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG281749.
HOVERGENiHBG051863.
InParanoidiQ15486.
PhylomeDBiQ15486.

Family and domain databases

Gene3Di2.60.40.320. 1 hit.
InterProiIPR013812. Glyco_hydro_2/20_Ig-like.
IPR006102. Glyco_hydro_2_Ig-like.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 1 hit.

Sequencei

Sequence statusi: Complete.

Q15486-1 [UniParc]FASTAAdd to Basket

« Hide

MDRSNPVKPA LDYFSNRLVN YQISVKCSNQ FKLEVCLLNA ENKVVDNQAG    50
TQGQLKVLGA NLWWPYLMHE HPASLYSWED GDCSHQSLGP LPACDLCDQL 100
HLRSRQGGSV CGCDPCEQLL LLVSQLRAPG VDSAAAGRPV 140
Length:140
Mass (Da):15,381
Last modified:September 2, 2008 - v3
Checksum:i80CA4B489C81A48D
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti15 – 151S → L in CAA58278. 1 Publication
Sequence conflicti74 – 741S → Y in CAA58278. 1 Publication
Sequence conflicti74 – 741S → Y in AAP35406. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83299 mRNA. Translation: CAA58278.1.
AK289832 mRNA. Translation: BAF82521.1.
AK315849 mRNA. Translation: BAF98740.1.
BT006760 mRNA. Translation: AAP35406.1.
AL009030 Genomic DNA. Translation: CAC69829.1.
AL009030 Genomic DNA. Translation: CAC69830.1.
PIRiI38232.
RefSeqiXP_006726287.1. XM_006726224.1.
UniGeneiHs.582500.
Hs.631974.
Hs.652536.
Hs.654588.

Genome annotation databases

GeneIDi100653061.
KEGGihsa:100653061.

Polymorphism databases

DMDMi205371787.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83299 mRNA. Translation: CAA58278.1 .
AK289832 mRNA. Translation: BAF82521.1 .
AK315849 mRNA. Translation: BAF98740.1 .
BT006760 mRNA. Translation: AAP35406.1 .
AL009030 Genomic DNA. Translation: CAC69829.1 .
AL009030 Genomic DNA. Translation: CAC69830.1 .
PIRi I38232.
RefSeqi XP_006726287.1. XM_006726224.1.
UniGenei Hs.582500.
Hs.631974.
Hs.652536.
Hs.654588.

3D structure databases

ProteinModelPortali Q15486.
SMRi Q15486. Positions 18-91.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q15486. 7 interactions.
MINTi MINT-1373382.

Polymorphism databases

DMDMi 205371787.

Proteomic databases

PaxDbi Q15486.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100653061.
KEGGi hsa:100653061.

Organism-specific databases

GeneCardsi GC05P021337.
HGNCi HGNC:13670. GUSBP1.
neXtProti NX_Q15486.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG281749.
HOVERGENi HBG051863.
InParanoidi Q15486.
PhylomeDBi Q15486.

Miscellaneous databases

NextBioi 34055837.

Gene expression databases

Genevestigatori Q15486.

Family and domain databases

Gene3Di 2.60.40.320. 1 hit.
InterProi IPR013812. Glyco_hydro_2/20_Ig-like.
IPR006102. Glyco_hydro_2_Ig-like.
[Graphical view ]
SUPFAMi SSF49303. SSF49303. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complex repetitive arrangements of gene sequence in the candidate region of the spinal muscular atropy gene in 5q13."
    Theodosiou A.M., Morrison K.E., Nesbit A.M., Daniels R.J., Campbell L., Francis M.J., Christodoulou Z., Davies K.E.
    Am. J. Hum. Genet. 55:1209-1217(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Fetal brain.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain and Thymus.
  3. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
    Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiGUSP1_HUMAN
AccessioniPrimary (citable) accession number: Q15486
Secondary accession number(s): A6NLY8
, A8K1B7, Q969T8, Q9BUH2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: September 2, 2008
Last modified: May 14, 2014
This is version 111 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene. Compared to other members of the glycosyl hydrolase 2 family this putative protein is truncated in both the N- and C-terminal regions and thus probably lacks enzymatic activity.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi