Reviewed, UniProtKB/Swiss-Prot Q15378 (RBY1H_HUMAN)

Names and origin

Protein names

Recommended name:
    Putative RNA-binding motif protein, Y chromosome, family 1 member H
Alternative name(s):
    Y chromosome RNA recognition motif protein

Gene names

Name:	RBMY1H
Synonyms:	YRRM

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	356 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Caution	Could be the product of pseudogene.
Sequence caution	The sequence AAC16919.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	spermatogenesis Ref.2 Non-traceable author statement. Source: UniProtKB
Molecular function	RNA binding Ref.2 Non-traceable author statement. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 356	356	Putative RNA-binding motif protein, Y chromosome, family 1 member H		PRO_0000337198
Regions
	Compositional bias	114 – 200	87	Arg-rich
Experimental info
	Sequence conflict	204	1	P → L in AAC16920. Ref.2
	Sequence conflict	213	1	D → A in AAC16920. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q15378-1 [UniParc]. Last modified May 20, 2008. Version 2. Checksum: DC734E4B42D616F7	FASTA	356	40,884
	10 20 30 40 50 60 MSYSRGLIPV KRGPSSRSGG PPPKKSAPSA VARSNSWMGS QGPMSQRREN YGVPPRRATI 70 80 90 100 110 120 SSWRNDRMST RHDGYATNDG NHPSSRETRD YAPPHRDYAY RDYGHSSWDE HSSRGYRNHR 130 140 150 160 170 180 SSRETRDYAP PSRGHAYRDY GHSRRDESYS RGYRNRRSSR ETREYAPPSR GHGYRDYGHS 190 200 210 220 230 240 RRHESYSRGY RNHPSSRETR DYAPPHRDYA YRDYGHSSWD EHSSRGYSYH DGYGEALGRD 250 260 270 280 290 300 HSEHLSGSSY RDALQRYGTS HGAPPARGPR MSYGGSTCHA YSNTRDRYGR SWESYSSCGD 310 320 330 340 350 FHYCDREHVC RKDQRNPPSL GRVLPDPREA YGSSSYVASI VDGGESRSEK GDSSRY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes." Skaletsky H., Kuroda-Kawaguchi T., Minx P.J., Cordum H.S., Hillier L.W., Brown L.G., Repping S., Pyntikova T., Ali J., Bieri T., Chinwalla A., Delehaunty A., Delehaunty K., Du H., Fewell G., Fulton L., Fulton R., Graves T.A. , Hou S.-F., Latrielle P., Leonard S., Mardis E., Maupin R., McPherson J., Miner T., Nash W., Nguyen C., Ozersky P., Pepin K., Rock S., Rohlfing T., Scott K., Schultz B., Strong C., Tin-Wollam A., Yang S.-P., Waterston R.H., Wilson R.K., Rozen S., Page D.C. Nature 423:825-837(2003) [PubMed: 12815422] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene." Chai N.-N., Zhou H., Hernandez J., Najmabadi H., Bhasin S., Yen P.H. Genomics 49:283-289(1998) [PubMed: 9598316] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-80, NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 192-356.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC010141 Genomic DNA. No translation available. U36613, U36611, U36612 Genomic DNA. Translation: AAC16919.1. Sequence problems. U36615, U36614 Genomic DNA. Translation: AAC16920.1.
IPI	IPI00893533.
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENST00000383020; ENSP00000372484; ENSG00000242875; Homo sapiens. [Genome view]
Organism-specific databases
GeneCards	GC0YP022064.
HGNC	HGNC:9916. RBMY1H.
PharmGKB	PA34283.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q15378.
Gene expression databases
Bgee	Q15378.
Genevestigator	Q15378.
Family and domain databases
InterPro	IPR012604. RBM1CTR. IPR015462. Y_Chr_RRM. [Graphical view]
PANTHER	PTHR10432:SF22. Y_Chr_RRM. 1 hit.
Pfam	PF08081. RBM1CTR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RBY1H_HUMAN

Accession

Primary (citable) accession number: Q15378
Secondary accession number(s): Q15379

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	November 24, 2009
This is version 41 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.