Unreviewed, UniProtKB/TrEMBL Q15136 (Q15136_HUMAN)

Names and origin

Protein names

Submitted name:
    Protein kinase A-alpha EMBL AAA60094.1

Gene names

Name:

KIN27 EMBL AAA60094.1

Organism

Homo sapiens (Human) EMBL AAA60094.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	207 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the protein kinase superfamily.

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304V2 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305V3 Transferase
Gene Ontology (GO)
Biological process	mesoderm formation Inferred from electronic annotation. Source: Compara peptidyl-serine phosphorylation Inferred from electronic annotation. Source: Compara positive regulation of protein export from nucleus Inferred from electronic annotation. Source: Compara protein amino acid autophosphorylation Inferred from electronic annotation. Source: Compara regulation of cellular respiration Inferred from electronic annotation. Source: Compara regulation of synaptic transmission, glutamatergic Inferred from electronic annotation. Source: Compara
Cellular component	Golgi apparatus Inferred from electronic annotation. Source: Compara membrane fraction Inferred from electronic annotation. Source: Compara mitochondrion Inferred from electronic annotation. Source: Compara neuromuscular junction Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara protein complex Inferred from electronic annotation. Source: Compara
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cAMP-dependent protein kinase activity Inferred from electronic annotation. Source: Compara protein complex binding Inferred from electronic annotation. Source: Compara protein kinase binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAA60094.1

Sequences

	Sequence		Length	Mass (Da)
	Q15136-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: C901E1EA7437EA58	FASTA	207	23,954
	10 20 30 40 50 60 EFLAKAKEDF LKKWESPAQN TAHLDQFERI KTLGTGSFGR VMLVKHKETG NHYAMKILDK 70 80 90 100 110 120 QKVVKLKQIE HTLNEKRILQ AVNFPFLVKL EFSFKDNSNL YMVMEYVPGG EMFSHLRRIG 130 140 150 160 170 180 RFSEPHARFY AAQIVLTFEY LHSLDLIYRD LKPENLLIDQ QGYIQVTDFG FAKRVKGRTW 190 200 TLCGTPEYLA PEIILSKVGA SPALPFP

References

[1]	"Mechanism of interferon action. cDNA structure and regulation of a novel splice-site variant of the catalytic subunit of human protein kinase A from interferon-treated human cells." Thomis D.C., Floyd-Smith G., Samuel C.E. J. Biol. Chem. 267:10723-10728(1992) [PubMed: 1375229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Amnion EMBL AAA60094.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M80335 mRNA. Translation: AAA60094.1.
IPI	IPI00217960.
PIR	A38143.
UniGene	Hs.631630
3D structure databases
HSSP	HSSP built from PDB template 1Q8U based on UniProtKB P00517.
SMR	Q15136. Positions 1-197.
ModBase	Search...
Protein-protein interaction databases
STRING	Q15136.
Genome annotation databases
Ensembl	ENST00000308677; ENSP00000309591; ENSG00000072062; Homo sapiens. [Genome view] ENST00000350356; ENSP00000340940; ENSG00000072062; Homo sapiens. [Genome view]
UCSC	uc002myd.2. human.
Organism-specific databases
HGNC	HGNC:9380. PRKACA.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q15136.
Gene expression databases
ArrayExpress	Q15136.
Bgee	Q15136.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q15136_HUMAN

Accession

Primary (citable) accession number: Q15136

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	January 19, 2010
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.