Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized protein KIAA0040

Gene

KIAA0040

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein KIAA0040
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:28950. KIAA0040.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA128394552.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 153153Uncharacterized protein KIAA0040PRO_0000050715Add
BLAST

Proteomic databases

PaxDbiQ15053.
PRIDEiQ15053.

Expressioni

Gene expression databases

CleanExiHS_KIAA0040.
ExpressionAtlasiQ15053. baseline and differential.
GenevisibleiQ15053. HS.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
MDFIQ997503EBI-2805673,EBI-724076

Protein-protein interaction databases

BioGridi115029. 2 interactions.
IntActiQ15053. 2 interactions.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00620000089392.

Sequencei

Sequence statusi: Complete.

Q15053-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHYVHVHRVT TQPRNKPQTK CPSGGQSQGP RGQFLDTVLA AMCPIAMLLT
60 70 80 90 100
ADPGMPPTCL WHTPHAKHKE HLSIHLNMVP KCVHMHVTHT HTNSGSRYVG
110 120 130 140 150
KYILLIKWSL AMYFVQGSTL STVTKMSHGK ALPDSDTYIQ FPNQQGPHTP

SIP
Length:153
Mass (Da):17,035
Last modified:November 1, 1996 - v1
Checksum:iCAC3F8AF16821935
GO

Sequence cautioni

The sequence BAA05022.2 differs from that shown. Reason: Erroneous initiation. Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti26 – 261Q → K.
Corresponds to variant rs2269650 [ dbSNP | Ensembl ].
VAR_020040

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D25539 mRNA. Translation: BAA05022.2. Different initiation.
AK292691 mRNA. Translation: BAF85380.1.
AL049799 mRNA. Translation: CAB42560.1.
AL049800 mRNA. Translation: CAB42561.1.
Z99715 Genomic DNA. No translation available.
CH471067 Genomic DNA. Translation: EAW90987.1.
RefSeqiNP_001156365.1. NM_001162893.1.
NP_001156366.1. NM_001162894.1.
NP_001156367.1. NM_001162895.1.
NP_001306159.1. NM_001319230.1.
NP_001306160.1. NM_001319231.1.
NP_055471.2. NM_014656.2.
XP_011508484.1. XM_011510182.1.
XP_011508485.1. XM_011510183.1.
UniGeneiHs.518138.

Genome annotation databases

EnsembliENST00000619513; ENSP00000478803; ENSG00000235750.
GeneIDi9674.
KEGGihsa:9674.
UCSCiuc057nmk.1. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D25539 mRNA. Translation: BAA05022.2. Different initiation.
AK292691 mRNA. Translation: BAF85380.1.
AL049799 mRNA. Translation: CAB42560.1.
AL049800 mRNA. Translation: CAB42561.1.
Z99715 Genomic DNA. No translation available.
CH471067 Genomic DNA. Translation: EAW90987.1.
RefSeqiNP_001156365.1. NM_001162893.1.
NP_001156366.1. NM_001162894.1.
NP_001156367.1. NM_001162895.1.
NP_001306159.1. NM_001319230.1.
NP_001306160.1. NM_001319231.1.
NP_055471.2. NM_014656.2.
XP_011508484.1. XM_011510182.1.
XP_011508485.1. XM_011510183.1.
UniGeneiHs.518138.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115029. 2 interactions.
IntActiQ15053. 2 interactions.

Proteomic databases

PaxDbiQ15053.
PRIDEiQ15053.

Protocols and materials databases

DNASUi9674.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000619513; ENSP00000478803; ENSG00000235750.
GeneIDi9674.
KEGGihsa:9674.
UCSCiuc057nmk.1. human.

Organism-specific databases

CTDi9674.
GeneCardsiKIAA0040.
HGNCiHGNC:28950. KIAA0040.
MIMi616696. gene.
neXtProtiNX_Q15053.
PharmGKBiPA128394552.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00620000089392.

Miscellaneous databases

ChiTaRSiKIAA0040. human.
GenomeRNAii9674.
PROiQ15053.
SOURCEiSearch...

Gene expression databases

CleanExiHS_KIAA0040.
ExpressionAtlasiQ15053. baseline and differential.
GenevisibleiQ15053. HS.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1."
    Nomura N., Miyajima N., Sazuka T., Tanaka A., Kawarabayasi Y., Sato S., Nagase T., Seki N., Ishikawa K., Tabata S.
    DNA Res. 1:27-35(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Bone marrow.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Thymus.
  3. Rhodes S.
    Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiK0040_HUMAN
AccessioniPrimary (citable) accession number: Q15053
Secondary accession number(s): A8K9H6, Q2NKQ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.