Q15020 (SART3_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Squamous cell carcinoma antigen recognized by T-cells 3
Short name=SART-3
Short name=hSART-3

Alternative name(s):
Tat-interacting protein of 110 kDa
Short name=Tip110

Gene names

Name:	SART3
Synonyms:	KIAA0156, TIP110

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	963 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Regulates Tat transactivation activity through direct interaction. May be a cellular factor for HIV-1 gene expression and viral replication. Ref.2
Subunit structure	Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6 snRNAs. Interacts with HIV-1 Tat. Interacts with EIF2C1 and EIF2C2. Ref.2 Ref.7 Ref.9
Subcellular location	Cytoplasm. Nucleus speckle. Note: Localized in speckles. Expressed in the nucleus of all of the malignant tumor cell lines tested and the majority of cancer tissues with various histologies, including squamous cell carcinomas (SCC), adenocarcinomas, melanomas and leukemias cells. However, this protein is undetectable in the nucleus of any cell lines of nonmalignant cells or normal tissues, except for the testis. Expressed in the cytoplasm of all the proliferating cells, including normal and malignant cells, but not in normal tissues, except for the testis and the fetal liver. Ref.1 Ref.2
Tissue specificity	Ubiquitously expressed. Ref.2
Involvement in disease	Disseminated superficial actinic porokeratosis 1 (DSAP1) [MIM:175900]: Autosomal dominant disorder, characterized by multiple superficial keratotic lesions surrounded by a slightly raised keratotic border, developing during the third or fourth decade of life on sun-exposed areas of skin. Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.16
Sequence similarities	Contains 8 HAT repeats. Contains 2 RRM (RNA recognition motif) domains.

Ontologies

Keywords
Cellular component	Cytoplasm Nucleus
Coding sequence diversity	Alternative splicing Polymorphism
Disease	Disease mutation
Domain	Coiled coil Repeat
Ligand	RNA-binding
PTM	Acetylation Phosphoprotein
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	RNA processing Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from direct assay. Source: HPA intracellular membrane-bounded organelle Inferred from direct assay. Source: HPA nuclear speck Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
RNPS1	Q15287	5	EBI-308619,EBI-395959

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q15020-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q15020-2)

The sequence of this isoform differs from the canonical sequence as follows:
     351-364: SQYLDRQLKVKDLV → RSTTESKGFGFICT
     365-963: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Isoform 3 (identifier: Q15020-3)

The sequence of this isoform differs from the canonical sequence as follows:
     105-129: LSINVYDYNCHVDLIRLLRLEGELT → VGPGVGSGHLPVFQVLGSPCPGPPP
     130-963: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

1

1

Removed Ref.8

Chain

2 – 963

962

Squamous cell carcinoma antigen recognized by T-cells 3

PRO_0000223313

Regions

Repeat

126 – 158

33

HAT 1

Repeat

164 – 195

32

HAT 2

Repeat

201 – 237

37

HAT 3

Repeat

242 – 275

34

HAT 4

Repeat

324 – 356

33

HAT 5

Repeat

359 – 391

33

HAT 6

Repeat

394 – 430

37

HAT 7

Repeat

487 – 520

34

HAT 8

Domain

704 – 782

79

RRM 1

Domain

801 – 878

78

RRM 2

Region

600 – 670

71

Required for nuclear localization

Coiled coil

21 – 46

26

Potential

Coiled coil

82 – 110

29

Potential

Coiled coil

559 – 619

61

Potential

Motif

601 – 617

17

Nuclear localization signal Potential

Compositional bias

89 – 92

4

Poly-Glu

Compositional bias

612 – 616

5

Poly-Lys

Amino acid modifications

Modified residue

2

1

N-acetylalanine Ref.8 Ref.11 Ref.12 Ref.14

Modified residue

10

1

Phosphoserine Ref.14

Modified residue

16

1

Phosphoserine Ref.6

Modified residue

852

1

Phosphoserine Ref.10

Natural variations

Alternative sequence

105 – 129

25

LSINV…EGELT → VGPGVGSGHLPVFQVLGSPC PGPPP in isoform 3.

VSP_017248

Alternative sequence

130 – 963

834

Missing in isoform 3.

VSP_017249

Alternative sequence

351 – 364

14

SQYLD…VKDLV → RSTTESKGFGFICT in isoform 2.

VSP_017250

Alternative sequence

365 – 963

599

Missing in isoform 2.

VSP_017251

Natural variant

23

1

D → E. Ref.4
Corresponds to variant rs2072579 [ dbSNP | Ensembl ].

VAR_038802

Natural variant

591

1

V → M in DSAP1. Ref.16

VAR_038683

Natural variant

621

1

E → D.
Corresponds to variant rs2287546 [ dbSNP | Ensembl ].

VAR_038684

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

963

Helix Strand Turn

Details...

Beta strand

803 – 807

5

Helix

814 – 821

8

Turn

822 – 824

3

Beta strand

827 – 834

8

Beta strand

840 – 850

11

Helix

851 – 861

11

Beta strand

864 – 868

5

Beta strand

870 – 875

6

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 06B26CEB8B19102A	FASTA	963	109,935
	10 20 30 40 50 60 MATAAETSAS EPEAESKAGP KADGEEDEVK AARTRRKVLS RAVAAATYKT MGPAWDQQEE 70 80 90 100 110 120 GVSESDGDEY AMASSAESSP GEYEWEYDEE EEKNQLEIER LEEQLSINVY DYNCHVDLIR 130 140 150 160 170 180 LLRLEGELTK VRMARQKMSE IFPLTEELWL EWLHDEISMA QDGLDREHVY DLFEKAVKDY 190 200 210 220 230 240 ICPNIWLEYG QYSVGGIGQK GGLEKVRSVF ERALSSVGLH MTKGLALWEA YREFESAIVE 250 260 270 280 290 300 AARLEKVHSL FRRQLAIPLY DMEATFAEYE EWSEDPIPES VIQNYNKALQ QLEKYKPYEE 310 320 330 340 350 360 ALLQAEAPRL AEYQAYIDFE MKIGDPARIQ LIFERALVEN CLVPDLWIRY SQYLDRQLKV 370 380 390 400 410 420 KDLVLSVHNR AIRNCPWTVA LWSRYLLAME RHGVDHQVIS VTFEKALNAG FIQATDYVEI 430 440 450 460 470 480 WQAYLDYLRR RVDFKQDSSK ELEELRAAFT RALEYLKQEV EERFNESGDP SCVIMQNWAR 490 500 510 520 530 540 IEARLCNNMQ KARELWDSIM TRGNAKYANM WLEYYNLERA HGDTQHCRKA LHRAVQCTSD 550 560 570 580 590 600 YPEHVCEVLL TMERTEGSLE DWDIAVQKTE TRLARVNEQR MKAAEKEAAL VQQEEEKAEQ 610 620 630 640 650 660 RKRARAEKKA LKKKKKIRGP EKRGADEDDE KEWGDDEEEQ PSKRRRVENS IPAAGETQNV 670 680 690 700 710 720 EVAAGPAGKC AAVDVEPPSK QKEKAASLKR DMPKVLHDSS KDSITVFVSN LPYSMQEPDT 730 740 750 760 770 780 KLRPLFEACG EVVQIRPIFS NRGDFRGYCY VEFKEEKSAL QALEMDRKSV EGRPMFVSPC 790 800 810 820 830 840 VDKSKNPDFK VFRYSTSLEK HKLFISGLPF SCTKEELEEI CKAHGTVKDL RLVTNRAGKP 850 860 870 880 890 900 KGLAYVEYEN ESQASQAVMK MDGMTIKENI IKVAISNPPQ RKVPEKPETR KAPGGPMLLP 910 920 930 940 950 960 QTYGARGKGR TQLSLLPRAL QRPSAAAPQA ENGPAAAPAV AAPAATEAPK MSNADFAKLF LRK
	Isoform 2 [UniParc]. Checksum: D86B2562A7FA2E4E	FASTA	364	41,829
	10 20 30 40 50 60 MATAAETSAS EPEAESKAGP KADGEEDEVK AARTRRKVLS RAVAAATYKT MGPAWDQQEE 70 80 90 100 110 120 GVSESDGDEY AMASSAESSP GEYEWEYDEE EEKNQLEIER LEEQLSINVY DYNCHVDLIR 130 140 150 160 170 180 LLRLEGELTK VRMARQKMSE IFPLTEELWL EWLHDEISMA QDGLDREHVY DLFEKAVKDY 190 200 210 220 230 240 ICPNIWLEYG QYSVGGIGQK GGLEKVRSVF ERALSSVGLH MTKGLALWEA YREFESAIVE 250 260 270 280 290 300 AARLEKVHSL FRRQLAIPLY DMEATFAEYE EWSEDPIPES VIQNYNKALQ QLEKYKPYEE 310 320 330 340 350 360 ALLQAEAPRL AEYQAYIDFE MKIGDPARIQ LIFERALVEN CLVPDLWIRY RSTTESKGFG FICT
	Isoform 3 [UniParc]. Checksum: B41FC49C1C5E4C33	FASTA	129	13,773
	10 20 30 40 50 60 MATAAETSAS EPEAESKAGP KADGEEDEVK AARTRRKVLS RAVAAATYKT MGPAWDQQEE 70 80 90 100 110 120 GVSESDGDEY AMASSAESSP GEYEWEYDEE EEKNQLEIER LEEQVGPGVG SGHLPVFQVL GSPCPGPPP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of a gene coding for a protein possessing shared tumor epitopes capable of inducing HLA-A24-restricted cytotoxic T lymphocytes in cancer patients." Yang D., Nakao M., Shichijo S., Sasatomi T., Takasu H., Matsumoto H., Mori K., Hayashi A., Yamana H., Shirouzu K., Itoh K. Cancer Res. 59:4056-4063(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION.
[2]	"HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110." Liu Y., Li J., Kim B.O., Pace B.S., He J.J. J. Biol. Chem. 277:23854-23863(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY, SUBCELLULAR LOCATION, FUNCTION, INTERACTION WITH TAT. Tissue: Fetal brain.
[3]	"Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1." Nagase T., Seki N., Tanaka A., Ishikawa K., Nomura N. DNA Res. 2:167-174(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Bone marrow.
[4]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT GLU-23. Tissue: Thalamus.
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3). Tissue: Brain, Eye, Skin and Uterus.
[6]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-16, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[7]	"Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells." Hoeck J., Weinmann L., Ender C., Ruedel S., Kremmer E., Raabe M., Urlaub H., Meister G. EMBO Rep. 8:1052-1060(2007) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH EIF2C1 AND EIF2C2.
[8]	Bienvenut W.V., Dhillon A.S., Kolch W. Submitted (FEB-2008) to UniProtKB Cited for: PROTEIN SEQUENCE OF 2-17; 121-130; 233-243; 295-322; 329-335; 350-356; 360-370; 452-463; 494-502; 555-568; 646-669; 758-768 AND 911-918, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT ALA-2, MASS SPECTROMETRY. Tissue: Hepatoma.
[9]	"Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme." Jeronimo C., Forget D., Bouchard A., Li Q., Chua G., Poitras C., Therien C., Bergeron D., Bourassa S., Greenblatt J., Chabot B., Poirier G.G., Hughes T.R., Blanchette M., Price D.H., Coulombe B. Mol. Cell 27:262-274(2007) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION IN THE 7SK SNRNP COMPLEX.
[10]	"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J. Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-852, MASS SPECTROMETRY. Tissue: Embryonic kidney.
[11]	"Large-scale proteomics analysis of the human kinome." Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G., Mann M., Daub H. Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, MASS SPECTROMETRY.
[12]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[13]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[14]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10, MASS SPECTROMETRY.
[15]	"Solution structure of the RNA binding domain of squamous cell carcinoma antigen recognized by T cells 3." RIKEN structural genomics initiative (RSGI) Submitted (APR-2007) to the PDB data bank Cited for: STRUCTURE BY NMR OF 791-877.
[16]	"A mutation in SART3 gene in a Chinese pedigree with disseminated superficial actinic porokeratosis." Zhang Z.H., Niu Z.M., Yuan W.T., Zhao J.J., Jiang F.X., Zhang J., Chai B., Cui F., Chen W., Lian C.H., Xiang L.H., Xu S.J., Liu W.D., Zheng Z.Z., Huang W. Br. J. Dermatol. 152:658-663(2005) [PubMed] [Europe PMC] [Abstract] Cited for: VARIANT DSAP1 MET-591.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF387506 mRNA. Translation: AAK69347.1.
AB020880 mRNA. Translation: BAA78384.1.
D63879 mRNA. Translation: BAA09929.1.
AK290209 mRNA. Translation: BAF82898.1.
BC032601 mRNA. Translation: AAH32601.1.
BC041638 mRNA. Translation: AAH41638.1.
BC093784 mRNA. Translation: AAH93784.1.
BC103706 mRNA. Translation: AAI03707.1.
BC111983 mRNA. Translation: AAI11984.1.

IPI

IPI00006025.
IPI00383381.
IPI01022779.

RefSeq

NP_055521.1. NM_014706.3.

UniGene

Hs.584842.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2DO4	NMR	-	A	791-877	[»]

ProteinModelPortal

Q15020.

ModBase

Search...

Protein-protein interaction databases

IntAct

Q15020. 28 interactions.

MINT

MINT-2867335.

STRING

9606.ENSP00000228284.

PTM databases

PhosphoSite

Q15020.

Polymorphism databases

DMDM

74762140.

Proteomic databases

PaxDb

Q15020.

PeptideAtlas

Q15020.

PRIDE

Q15020.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

Ensembl

ENST00000228284; ENSP00000228284; ENSG00000075856.
ENST00000546611; ENSP00000448554; ENSG00000075856.
ENST00000546728; ENSP00000449743; ENSG00000075856.

GeneID

9733.

KEGG

hsa:9733.

UCSC

uc001tmy.1. human.
uc001tnb.3. human.

Organism-specific databases

CTD

9733.

GeneCards

GC12M108915.

HGNC

HGNC:16860. SART3.

HPA

HPA044322.

MIM

175900. phenotype.
611684. gene.

neXtProt

NX_Q15020.

Orphanet

79152. Disseminated superficial actinic porokeratosis.

PharmGKB

PA34948.

HUGE

Search...

GenAtlas

Search...

Phylogenomic databases

eggNOG

NOG321927.

HOGENOM

HOG000063708.

HOVERGEN

HBG053888.

InParanoid

Q15020.

OMA

SQAVMKM.

OrthoDB

EOG4RXXZG.

PhylomeDB

Q15020.

Gene expression databases

ArrayExpress

Q15020.

Bgee

Q15020.

CleanEx

HS_SART3.

Genevestigator

Q15020.

GermOnline

ENSG00000075856. Homo sapiens.

Family and domain databases

Gene3D

3.30.70.330. 2 hits.

InterPro

IPR003107. HAT.
IPR008669. LSM_interact.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]

Pfam

PF05391. Lsm_interact. 1 hit.
PF00076. RRM_1. 2 hits.
[Graphical view]

SMART

SM00386. HAT. 7 hits.
SM00360. RRM. 2 hits.
[Graphical view]

PROSITE

PS50102. RRM. 2 hits.
[Graphical view]

ProtoNet

Search...

Other

ChiTaRS

SART3. human.

EvolutionaryTrace

Q15020.

GenomeRNAi

9733.

NextBio

36616.

SOURCE

Search...

Entry information

Entry name

SART3_HUMAN

Accession

Primary (citable) accession number: Q15020
Secondary accession number(s): A8K2E4 , Q2M2H0, Q58F06, Q8IUS1, Q96J95

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 7, 2006
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 116 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.