Q14FS1 (Q14FS1_FRAT1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase EMBL CAL09738.1
EC=4.1.1.15 EMBL CAL09738.1

Gene names

Name:	gad EMBL CAL09738.1
Ordered Locus Names:	FTF1722c

Organism

Francisella tularensis subsp. tularensis (strain FSC 198) [Complete proteome] [HAMAP] EMBL CAL09738.1

Taxonomic identifier

393115 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella › Francisella tularensis › Francisella tularensis subsp. tularensis

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382 EMBL CAL09738.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q14FS1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 2A48F8FD23CA64D4	FASTA	448	50,815
	10 20 30 40 50 60 MALHGKKDTI DNLDFFEQSL PKFKLPLNSQ DPLEVYQEIK DELMLDGNSK QNLATFCQTE 70 80 90 100 110 120 VDDFIHKLMD DCIDKNMIDK DEYPQTAEIE SRCVNILANL WNSSAENAIG CSTTGSSEAA 130 140 150 160 170 180 MLGGMAMKWR WRDKMKAQGK DYTKPNLVTG PVQVCWHKFA RYWDIELREI PMSNESLIMT 190 200 210 220 230 240 PEAVLERCDE NTIGVVPTLG VTFTGQYEPV EQVCKALDDF ERQTGVDIPV HVDAASGGFL 250 260 270 280 290 300 APFVEPELKW DFRLPRVKSI NSSGHKFGLS PLGVGWVIWA DKKYLPDDLI FNVNYLGGNM 310 320 330 340 350 360 PAFALNFSRL GGQIVAQYYN FVRLGFEGYK KVHQLCYDVA EYIAKELRKM EIFEIIHAGE 370 380 390 400 410 420 GGIPAVSWSL KATKEYSLFD ISEKVRAKGW QIAAYTMPNN REDLVVMRVL VRRGFSYDLA 430 440 QLMIRDLVAV IDSLEGKLKI LKRSSFAH

References

[1]

"Genome sequencing shows that European isolates of Francisella tularensis subspecies tularensis are almost identical to US laboratory strain Schu S4." Chaudhuri R.R., Ren C.-P., Desmond L., Vincent G.A., Silman N.J., Brehm J.K., Elmore M.J., Hudson M.J., Forsman M., Isherwood K.E., Gurycova D., Minton N.P., Titball R.W., Pallen M.J., Vipond R. PLoS ONE 2:E352-E352(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FSC 198.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM286280 Genomic DNA. Translation: CAL09738.1.
RefSeq	YP_667757.1. NC_008245.1.
3D structure databases
ProteinModelPortal	Q14FS1.
SMR	Q14FS1. Positions 13-435.
ModBase	Search...
Protein-protein interaction databases
STRING	393115.FTF1722c.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAL09738; CAL09738; FTF1722c.
GeneID	4199207.
KEGG	ftf:FTF1722c.
PATRIC	17962740. VBIFraTul133500_2000.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0076.
HOGENOM	HOG000070228.
KO	K01580.
OMA	WESGHSS.
ProtClustDB	CLSK935148.
Enzyme and pathway databases
BioCyc	FTUL393115:GJUT-1768-MONOMER.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q14FS1_FRAT1

Accession

Primary (citable) accession number: Q14FS1

Entry history

Integrated into UniProtKB/TrEMBL:	August 22, 2006
Last sequence update:	August 22, 2006
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)