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Protein
Submitted name:

C-type lectin domain family 5 member A

Gene

CLEC5A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandLectinSAAS annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
C-type lectin domain family 5 member AImported
Submitted name:
CLEC5A proteinImported
Submitted name:
cDNA FLJ51846, highly similar to C-type lectin domain family 5 member AImported
Gene namesi
Name:CLEC5AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000258227.6
HGNCiHGNC:2054 CLEC5A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 27HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000258227

Expressioni

Gene expression databases

BgeeiENSG00000258227

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 161C-type lectinInterPro annotationAdd BLAST107

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00910000144330
HOGENOMiHOG000252978
HOVERGENiHBG081250

Family and domain databases

CDDicd03593 CLECT_NK_receptors_like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold
IPR033992 NKR-like_CTLD
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
SMARTiView protein in SMART
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS50041 C_TYPE_LECTIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q14DL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNWHMIISGL IVVVLKVVGM TLFLLYFPQI FNKSNDGFTT TRSYGTVCPK
60 70 80 90 100
DWEFYQARCF FLSTSESSWN ESRDFCKGKG STLAIVNTPE KLKFLQDITD
110 120 130 140 150
AEKYFIGLIY HREEKRWRWI NNSVFNGNVT NQNQNFNCAT IGLTKTFDAA
160
SCDISYRRIC EKNAK
Length:165
Mass (Da):19,149
Last modified:August 22, 2006 - v1
Checksum:i18AE66A663CCCA6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073647 Genomic DNA No translation available.
BC113099 mRNA Translation: AAI13100.1
AK295200 mRNA Translation: BAG58199.1
RefSeqiNP_001288096.1, NM_001301167.1
UniGeneiHs.446235

Genome annotation databases

EnsembliENST00000551012; ENSP00000446890; ENSG00000258227
GeneIDi23601
UCSCiuc010lnq.2 human

Similar proteinsi

Entry informationi

Entry nameiQ14DL9_HUMAN
AccessioniPrimary (citable) accession number: Q14DL9
Entry historyiIntegrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health