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Protein

Ubiquilin-like protein

Gene

Ubqlnl

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquilin-like protein
Gene namesi
Name:Ubqlnl
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:2685336. Ubqlnl.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 610610Ubiquilin-like proteinPRO_0000307792Add
BLAST

Proteomic databases

PaxDbiQ14DL0.
PRIDEiQ14DL0.

Expressioni

Gene expression databases

BgeeiQ14DL0.
CleanExiMM_UBQLNL.
GenevisibleiQ14DL0. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000056365.

Structurei

Secondary structure

1
610
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi564 – 5674Combined sources
Helixi569 – 57810Combined sources
Helixi583 – 59210Combined sources
Helixi597 – 60610Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2DNANMR-A557-610[»]
ProteinModelPortaliQ14DL0.
SMRiQ14DL0. Positions 28-101, 561-610.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ14DL0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini31 – 10575Ubiquitin-likePROSITE-ProRule annotationAdd
BLAST
Domaini562 – 60746UBAAdd
BLAST

Sequence similaritiesi

Contains 1 UBA domain.Curated
Contains 1 ubiquitin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0010. Eukaryota.
COG5272. LUCA.
GeneTreeiENSGT00390000005720.
HOGENOMiHOG000234878.
HOVERGENiHBG064537.
InParanoidiQ14DL0.
KOiK04523.
OMAiVAPYLWG.
OrthoDBiEOG754HP5.
TreeFamiTF314412.

Family and domain databases

InterProiIPR009060. UBA-like.
IPR015496. Ubiquilin.
IPR029071. Ubiquitin-rel_dom.
IPR000626. Ubiquitin_dom.
[Graphical view]
PANTHERiPTHR10677. PTHR10677. 2 hits.
PfamiPF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50053. UBIQUITIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q14DL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRIISRSPK MPQSRYTAGV PADGKISPGV IRVIVKTPGN QIIFTVADDT
60 70 80 90 100
LVRQFKEILS AHFKCQMEQL VLVFMGRLLK DHDTLSQRGI TDGHIIHVVI
110 120 130 140 150
KSKHGPRSLA HSFRNLVTNN PCHQDRNPKG NSSMVCQSAG MNETKVESSL
160 170 180 190 200
LMEPEAPKVG TESPEVGSLE HIAQVLENLC VQSLLSNMDF VHQMPPEQPY
210 220 230 240 250
MEELIQQNPE VSHLLDNSEI LCQTLELVRH LAIIQEIMQI QQPAQNPEYP
260 270 280 290 300
PNSQPFLGLE TVPNGNNHLG QSYVNNNDHM LNGVPDLLEG NCFTALLDEQ
310 320 330 340 350
VLEQVQTPSL SQPLPQEQWD QLSSSQVIYA NSCGLSSITP TNATPNHTNN
360 370 380 390 400
VSRENPAIVA TQGQSNVCAV QQPAEIPVLP TISINQKPQV DKDTTITLGI
410 420 430 440 450
SDQWLEEDLQ QSDDQTSSQI TGGMIQLLRN HPQMAAQMLL LMNTSQLNEQ
460 470 480 490 500
WRQETPTPLQ SSQLHDLLLA LANPKTSQAL LQIEHGLQLL ATEAPALLPY
510 520 530 540 550
IEPYLWGLGW LIPSICSYPD IVPWTWNVQD MAEPQCPESC HKSETVLQKV
560 570 580 590 600
QPPSGDPSHS LQAPEVRFSK EMECLQAMGF VNYNANLQAL IATDGDTNAA
610
IYKLKSSQGF
Length:610
Mass (Da):67,566
Last modified:July 27, 2011 - v2
Checksum:i48F57D85DA7CF840
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti17 – 171T → P in AAI11902 (PubMed:15489334).Curated
Sequence conflicti52 – 521V → G in BAC36434 (PubMed:16141072).Curated
Sequence conflicti58 – 581I → M in AAI11902 (PubMed:15489334).Curated
Sequence conflicti82 – 821H → Y in AAI11902 (PubMed:15489334).Curated
Sequence conflicti132 – 1321S → C in AAI11902 (PubMed:15489334).Curated
Sequence conflicti142 – 1421N → S in AAI11902 (PubMed:15489334).Curated
Sequence conflicti145 – 1451K → I in AAI11902 (PubMed:15489334).Curated
Sequence conflicti150 – 1501Missing in AAI11902 (PubMed:15489334).Curated
Sequence conflicti163 – 1631S → G in AAI11902 (PubMed:15489334).Curated
Sequence conflicti196 – 1961P → Q in AAI11902 (PubMed:15489334).Curated
Sequence conflicti256 – 2561F → Y in AAI11902 (PubMed:15489334).Curated
Sequence conflicti284 – 2841V → A in AAI11902 (PubMed:15489334).Curated
Sequence conflicti345 – 3451P → S in AAI11902 (PubMed:15489334).Curated
Sequence conflicti383 – 3831S → P in AAI11902 (PubMed:15489334).Curated
Sequence conflicti387 – 3871K → E in AAI11902 (PubMed:15489334).Curated
Sequence conflicti395 – 3951T → A in AAI11902 (PubMed:15489334).Curated
Sequence conflicti423 – 4231G → R in AAI13135 (PubMed:15489334).Curated
Sequence conflicti445 – 4451S → P in AAI11902 (PubMed:15489334).Curated
Sequence conflicti445 – 4451S → P in AAI13135 (PubMed:15489334).Curated
Sequence conflicti460 – 4601Q → H in AAI11902 (PubMed:15489334).Curated
Sequence conflicti517 – 5171S → G in AAI11902 (PubMed:15489334).Curated
Sequence conflicti522 – 5221V → E in BAC36434 (PubMed:16141072).Curated
Sequence conflicti553 – 5531P → L in AAI11902 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK076645 mRNA. Translation: BAC36434.1.
AC123830 Genomic DNA. No translation available.
BC111901 mRNA. Translation: AAI11902.1.
BC113134 mRNA. Translation: AAI13135.1.
CCDSiCCDS21611.1.
RefSeqiNP_941026.2. NM_198624.3.
UniGeneiMm.189668.

Genome annotation databases

EnsembliENSMUST00000059121; ENSMUSP00000056365; ENSMUSG00000051437.
GeneIDi244179.
KEGGimmu:244179.
UCSCiuc009ivl.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK076645 mRNA. Translation: BAC36434.1.
AC123830 Genomic DNA. No translation available.
BC111901 mRNA. Translation: AAI11902.1.
BC113134 mRNA. Translation: AAI13135.1.
CCDSiCCDS21611.1.
RefSeqiNP_941026.2. NM_198624.3.
UniGeneiMm.189668.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2DNANMR-A557-610[»]
ProteinModelPortaliQ14DL0.
SMRiQ14DL0. Positions 28-101, 561-610.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000056365.

Proteomic databases

PaxDbiQ14DL0.
PRIDEiQ14DL0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000059121; ENSMUSP00000056365; ENSMUSG00000051437.
GeneIDi244179.
KEGGimmu:244179.
UCSCiuc009ivl.1. mouse.

Organism-specific databases

CTDi143630.
MGIiMGI:2685336. Ubqlnl.

Phylogenomic databases

eggNOGiKOG0010. Eukaryota.
COG5272. LUCA.
GeneTreeiENSGT00390000005720.
HOGENOMiHOG000234878.
HOVERGENiHBG064537.
InParanoidiQ14DL0.
KOiK04523.
OMAiVAPYLWG.
OrthoDBiEOG754HP5.
TreeFamiTF314412.

Miscellaneous databases

EvolutionaryTraceiQ14DL0.
PROiQ14DL0.
SOURCEiSearch...

Gene expression databases

BgeeiQ14DL0.
CleanExiMM_UBQLNL.
GenevisibleiQ14DL0. MM.

Family and domain databases

InterProiIPR009060. UBA-like.
IPR015496. Ubiquilin.
IPR029071. Ubiquitin-rel_dom.
IPR000626. Ubiquitin_dom.
[Graphical view]
PANTHERiPTHR10677. PTHR10677. 2 hits.
PfamiPF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50053. UBIQUITIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Testis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. "Solution structure of RSGI RUH-056, a UBA domain from mouse cDNA."
    RIKEN structural genomics initiative (RSGI)
    Submitted (OCT-2006) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 556-609.

Entry informationi

Entry nameiUBQLN_MOUSE
AccessioniPrimary (citable) accession number: Q14DL0
Secondary accession number(s): E9QM12, Q14DR8, Q8BVT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 27, 2011
Last modified: June 8, 2016
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.