Q14DG0 (Q14DG0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
F-box protein, helicase, 18 EMBL AAI13376.1

Gene names

Name:

FBXO18 EMBL AAI13376.1

Organism

Homo sapiens (Human) EMBL AAI13376.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1043 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 F-box domain. RuleBase RU004534

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase EMBL AAI13376.1 Hydrolase
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro ATP-dependent DNA helicase activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q14DG0 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: D9608BA149F8FEC7	FASTA	1,043	117,614
	10 20 30 40 50 60 MRRFKRKHLT AIDCQHLARS HLAVTQPFGQ RWTNRDPNHG LYPKPRTKRG SRGQGSQRCI 70 80 90 100 110 120 PEFFLAGKQP CTNDMAKSNS VGQDSCQDSE GDMIFPAESS CALPQEGSAG PGSPGSAPPS 130 140 150 160 170 180 RKRSWSSEEE SNQATGTSRW DGVSKKAPRH HLSVPCTRPR EARQEAEDST SRLSAESGET 190 200 210 220 230 240 DQDAGDVGPD PIPDSYYGLL GTLPCQEALS HICSLPSEVL RHVFAFLPVE DLYWNLSLVC 250 260 270 280 290 300 HLWREIISDP LFIPWKKLYH RYLMNEEQAV SKVDGILSNC GIEKESDLCV LNLIRYTATT 310 320 330 340 350 360 KCSPSVDPER VLWSLRDHPL LPEAEACVRQ HLPDLYAAAG GVNIWALVAA VVLLSSSVND 370 380 390 400 410 420 IQRLLFCLRR PSSTVTMPDV TETLYCIAVL LYAMREKGIN ISNRIHYNIF YCLYLQENSC 430 440 450 460 470 480 TQATKVKEEP SVWPGKKTIQ LTHEQQLILN HKMEPLQVVK IMAFAGTGKT STLVKYAEKW 490 500 510 520 530 540 SQSRFLYVTF NKSIAKQAER VFPSNVICKT FHSMAYGHIG RKYQSKKKLN LFKLTPFMVN 550 560 570 580 590 600 SVLAEGKGGF IRAKLVCKTL ENFFASADEE LTIDHVPIWC KNSQGQRVMV EQSEKLNGVL 610 620 630 640 650 660 EASRLWDNMR KLGECTEEAH QMTHDGYLKL WQLSKPSLAS FDAIFVDEAQ DCTPAIMNIV 670 680 690 700 710 720 LSQPCGKIFV GDPHQQIYTF RGAVNALFTV PHTHVFYLTQ SFRFGVEIAY VGATILDVCK 730 740 750 760 770 780 RVRKKTLVGG NHQSGIRGDA KGQVALLSRT NANVFDEAVR VTEGEFPSRI HLIGGIKSFG 790 800 810 820 830 840 LDRIIDIWIL LQPEEERRKQ NLVIKDKFIR RWVHKEGFSG FKRYVTAAED KELEAKIAVV 850 860 870 880 890 900 EKYNIRIPEL VQRIEKCHIE DLDFAEYILG TVHKAKGLEF DTVHVLDDFV KVPCARHNLP 910 920 930 940 950 960 QLPHFRVESF SEDEWNLLYV AVTRAKKRLI MTKSLGNILT LAGEYFLQAE LTSNVLKTGV 970 980 990 1000 1010 1020 VRCCVGQCNN AIPVDTVLTM KKLPITYSNR KENKGGYLCH SCAEQRIGPL AFLTASPEQV 1030 1040 RAMERTVENI VLPRHEALLF LVF

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAI13376.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC113375 mRNA. Translation: AAI13376.1.
IPI	IPI00375254.
UniGene	Hs.498543.
3D structure databases
ProteinModelPortal	Q14DG0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q14DG0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG051568.
Gene expression databases
ArrayExpress	Q14DG0.
Family and domain databases
InterPro	IPR000212. DNA_helicase_UvrD/REP. IPR001810. F-box_dom_cyclin-like. IPR022364. F-box_dom_Skp2-like. [Graphical view]
PANTHER	PTHR11070. UvrD_helicase. 1 hit.
Pfam	PF00580. UvrD-helicase. 1 hit. [Graphical view]
SMART	SM00256. FBOX. 1 hit. [Graphical view]
SUPFAM	SSF81383. F-box_dom_Skp2-like. 1 hit.
PROSITE	PS50181. FBOX. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q14DG0_HUMAN

Accession

Primary (citable) accession number: Q14DG0

Entry history

Integrated into UniProtKB/TrEMBL:	August 22, 2006
Last sequence update:	August 22, 2006
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.