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Protein

UPF0472 protein C16orf72

Gene

C16orf72

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-30885-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0472 protein C16orf72
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:30103. C16orf72.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000182831.
PharmGKBiPA145149589.

Polymorphism and mutation databases

BioMutaiC16orf72.
DMDMi121940554.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002976271 – 275UPF0472 protein C16orf72Add BLAST275

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei167PhosphoserineCombined sources1
Modified residuei212PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ14CZ0.
MaxQBiQ14CZ0.
PaxDbiQ14CZ0.
PeptideAtlasiQ14CZ0.
PRIDEiQ14CZ0.

PTM databases

iPTMnetiQ14CZ0.
PhosphoSitePlusiQ14CZ0.

Expressioni

Gene expression databases

BgeeiENSG00000182831.
CleanExiHS_C16orf72.
ExpressionAtlasiQ14CZ0. baseline and differential.
GenevisibleiQ14CZ0. HS.

Organism-specific databases

HPAiHPA041568.
HPA067492.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
FAM9BQ8IZU03EBI-10234807,EBI-10175124

Protein-protein interaction databases

BioGridi118829. 5 interactors.
IntActiQ14CZ0. 3 interactors.
STRINGi9606.ENSP00000331720.

Structurei

3D structure databases

ProteinModelPortaliQ14CZ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0472 family.Curated

Phylogenomic databases

eggNOGiENOG410IJWS. Eukaryota.
ENOG410YYIF. LUCA.
GeneTreeiENSGT00390000002886.
HOGENOMiHOG000015768.
HOVERGENiHBG066226.
InParanoidiQ14CZ0.
OMAiAHQRSYD.
OrthoDBiEOG091G0HCR.
PhylomeDBiQ14CZ0.
TreeFamiTF323292.

Family and domain databases

InterProiIPR029196. DUF4588.
[Graphical view]
PfamiPF15251. DUF4588. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q14CZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEERKEEGEA EIQEHGPEHW FSKWERQCLA EAEQDEQLPP ELQEEAAAAA
60 70 80 90 100
QPEHKQQKLW HLFQNSATAV AQLYKDRVCQ QPGLSLWVPF QNAATAVTNL
110 120 130 140 150
YKESVDTHQR SFDIGIQIGY QRRNKDVLAW VKKRRRTIRR EDLISFLCGK
160 170 180 190 200
VPPPRNSRAP PRLTVVSPNR ATSTETSSSV ETDLQPFREA IALHGLSGAM
210 220 230 240 250
ASISVRSSTP GSPTHVSSGS NASRRRNGLH DVDLNTFISE EMALHLDNGG
260 270
TRKRTSAQCG DVITDSPTHK RNRMI
Length:275
Mass (Da):30,926
Last modified:August 22, 2006 - v1
Checksum:iE901B9A3C4A2B23C
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_034657221N → S.Corresponds to variant rs34869458dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC113570 mRNA. Translation: AAI13571.1.
CCDSiCCDS10538.1.
RefSeqiNP_054836.2. NM_014117.2.
UniGeneiHs.221497.
Hs.654689.
Hs.728924.

Genome annotation databases

EnsembliENST00000327827; ENSP00000331720; ENSG00000182831.
GeneIDi29035.
KEGGihsa:29035.
UCSCiuc002czm.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC113570 mRNA. Translation: AAI13571.1.
CCDSiCCDS10538.1.
RefSeqiNP_054836.2. NM_014117.2.
UniGeneiHs.221497.
Hs.654689.
Hs.728924.

3D structure databases

ProteinModelPortaliQ14CZ0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi118829. 5 interactors.
IntActiQ14CZ0. 3 interactors.
STRINGi9606.ENSP00000331720.

PTM databases

iPTMnetiQ14CZ0.
PhosphoSitePlusiQ14CZ0.

Polymorphism and mutation databases

BioMutaiC16orf72.
DMDMi121940554.

Proteomic databases

EPDiQ14CZ0.
MaxQBiQ14CZ0.
PaxDbiQ14CZ0.
PeptideAtlasiQ14CZ0.
PRIDEiQ14CZ0.

Protocols and materials databases

DNASUi29035.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000327827; ENSP00000331720; ENSG00000182831.
GeneIDi29035.
KEGGihsa:29035.
UCSCiuc002czm.4. human.

Organism-specific databases

CTDi29035.
GeneCardsiC16orf72.
H-InvDBHIX0026990.
HGNCiHGNC:30103. C16orf72.
HPAiHPA041568.
HPA067492.
neXtProtiNX_Q14CZ0.
OpenTargetsiENSG00000182831.
PharmGKBiPA145149589.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IJWS. Eukaryota.
ENOG410YYIF. LUCA.
GeneTreeiENSGT00390000002886.
HOGENOMiHOG000015768.
HOVERGENiHBG066226.
InParanoidiQ14CZ0.
OMAiAHQRSYD.
OrthoDBiEOG091G0HCR.
PhylomeDBiQ14CZ0.
TreeFamiTF323292.

Enzyme and pathway databases

BioCyciZFISH:G66-30885-MONOMER.

Miscellaneous databases

ChiTaRSiC16orf72. human.
GenomeRNAii29035.
PROiQ14CZ0.

Gene expression databases

BgeeiENSG00000182831.
CleanExiHS_C16orf72.
ExpressionAtlasiQ14CZ0. baseline and differential.
GenevisibleiQ14CZ0. HS.

Family and domain databases

InterProiIPR029196. DUF4588.
[Graphical view]
PfamiPF15251. DUF4588. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCP072_HUMAN
AccessioniPrimary (citable) accession number: Q14CZ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: August 22, 2006
Last modified: November 30, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.