Q14CE0 (Q14CE0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GPR64 protein EMBL AAI13980.1

Submitted name:
Uncharacterized protein Ensembl ENSP00000344972

Gene names

Name:

GPR64 Ensembl ENSP00000344972 EMBL AAI13980.1

Organism

Homo sapiens (Human) EMBL AAI13980.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	898 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 GPS domain. SAAS SAAS017981

Ontologies

Keywords
Cellular component	Cell membrane SAAS SAAS017981 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS017981
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	neuropeptide signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from direct assay. Source: HPA integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	G-protein coupled receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q14CE0 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: E4820F94AD64A73B	FASTA	898	98,720
	10 20 30 40 50 60 MVFSVRQCGH VGRTEEVLLT FKIFLVIICL HVVLVTSLEE DTDNSSLSPP PEVETTSLND 70 80 90 100 110 120 VTLSLLPSNE TGVKPQRNIC NLSSICNDSA FFRGEIMFQY DKESTVPQNQ HITNGTLTGV 130 140 150 160 170 180 LSLSELKRSE LNKTLQTLSE TYFIMCATAE AQSTLNCTFT IKLNNTMNAC AVIAALERVK 190 200 210 220 230 240 IRPMEHCCCS VRIPCPSSPE ELEKLQCDLQ DPIVCLADHP RGPPFSSSQS IPVVPRATVL 250 260 270 280 290 300 SQVPKATSFA EPPDYSPVTH NVPSPIGEIQ PLSPQPSAPI ASSPAIDMPP QSETISSPMP 310 320 330 340 350 360 QTHVSGTPPP VKASFSSPTV SAPANVNTTS APPVQTDIVN TSSISDLENQ VLQMEKALSL 370 380 390 400 410 420 GSLEPNLAGE MINQVSRLLH SPPDMLAPLA QRLLKVVDDI GLQLNFSNTT ISLTSPSLAL 430 440 450 460 470 480 AVIRVNASSF NTTTFVAQDP ANLQDELTVR CVFWDLGRNG GRGGWSDNGC SVKDRRLNET 490 500 510 520 530 540 ICTCSHLTSF GVLLDLSRTS VLPAQMMALT FITYIGCGLS SIFLSVTLVT YIAFEKIRRD 550 560 570 580 590 600 YPSKILIQLC AALLLLNLVF LLDSWIALYK MQGLCISVAV FLHYFLLVSF TWMGLEAFHM 610 620 630 640 650 660 YLALVKVFNT YIRKYILKFC IVGWGVPAVV VTIILTISPD NYGLGSYGKF PNGSPDDFCW 670 680 690 700 710 720 INNNAVFYIT VVGYFCVIFL LNVSMFIVVL VQLCRIKKKK QLGAQRKTSI QDLRSIAGLT 730 740 750 760 770 780 FLLGITWGFA FFAWGPVNVT FMYLFAIFNT LQGFFIFIFY CVAKENVRKQ WRRYLCCGKL 790 800 810 820 830 840 RLAENSDWSK TATNGLKKQT VNQGVSSSSN SLQSSSNSTN STTLLVNNDC SVHASGNGNA 850 860 870 880 890 STERNGVSFS VQNGDVCLHD FTGKQHMFNE KEDSCNGKGR MALRRTSKRG SLHFIEQM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI13980.1.
[2]	"The DNA sequence of the human X chromosome." Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C. , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R. Nature 434:325-337(2005) [PubMed: 15772651] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL732509 Genomic DNA. No translation available. AL732578 Genomic DNA. No translation available. BC113979 mRNA. Translation: AAI13980.1.
IPI	IPI00945059.
UniGene	Hs.146978.
3D structure databases
ProteinModelPortal	Q14CE0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q14CE0.
Protein family/group databases
MEROPS	S63.010.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000340581; ENSP00000344972; ENSG00000173698.
UCSC	uc010nfj.1. human.
Organism-specific databases
HGNC	HGNC:4516. GPR64.
GenAtlas	Search...
Phylogenomic databases
GeneTree	ENSGT00600000084404.
HOVERGEN	HBG051817.
Gene expression databases
ArrayExpress	Q14CE0.
Bgee	Q14CE0.
Family and domain databases
InterPro	IPR017981. GPCR_2-like. IPR000832. GPCR_2_secretin-like. IPR017983. GPCR_2_secretin-like_CS. IPR000203. GPS_dom. [Graphical view]
Pfam	PF00002. 7tm_2. 1 hit. PF01825. GPS. 1 hit. [Graphical view]
PRINTS	PR00249. GPCRSECRETIN.
SMART	SM00303. GPS. 1 hit. [Graphical view]
PROSITE	PS00650. G_PROTEIN_RECEP_F2_2. 1 hit. PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. PS50221. GPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q14CE0_HUMAN

Accession

Primary (citable) accession number: Q14CE0

Entry history

Integrated into UniProtKB/TrEMBL:	August 22, 2006
Last sequence update:	August 22, 2006
Last modified:	September 21, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.