Unreviewed, UniProtKB/TrEMBL Q14CD2 (Q14CD2_HUMAN)

Names and origin

Protein names

Submitted name:
    Nuclear receptor coactivator 2 EMBL AAI14384.1

Gene names

Name:

NCOA2 EMBL AAI14384.1

Organism

Homo sapiens (Human) EMBL AAI14384.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1464 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 basic helix-loop-helix (bHLH) domain. RuleBase RU000367V1 Spearmint SPM000014

Ontologies

Keywords
Biological process	Transcription Transcription regulation Spearmint SPM000014
Cellular component	Nucleus Spearmint SPM000014
Molecular function	Receptor
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	nuclear hormone receptor binding Inferred from electronic annotation. Source: InterPro receptor activity Inferred from electronic annotation. Source: UniProtKB-KW transcription coactivator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q14CD2-1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 58A76899187C3350	FASTA	1,464	159,138
	10 20 30 40 50 60 MSGMGENTSD PSRAETRKRK ECPDQLGPSP KRNTEKRNRE QENKYIEELA ELIFANFNDI 70 80 90 100 110 120 DNFNFKPDKC AILKETVKQI RQIKEQEKAA AANIDEVQKS DVSSTGQGVI DKDALGPMML 130 140 150 160 170 180 EALDGFFFVV NLEGNVVFVS ENVTQYLRYN QEELMNKSVY SILHVGDHTE FVKNLLPKSI 190 200 210 220 230 240 VNGGSWSGEP PRRNSHTFNC RMLVKPLPDS EEEGHDNQEA HQKYETMQCF AVSQPKSIKE 250 260 270 280 290 300 EGEDLQSCLI CVARRVPMKE RPVLPSSESF TTRQDLQGKI TSLDTSTMRA AMKPGWEDLV 310 320 330 340 350 360 RRCIQKFHAQ HEGESVSYAK RHHHEVLRQG LAFSQIYRFS LSDGTLVAAQ TKSKLIRSQT 370 380 390 400 410 420 TNEPQLVISL HMLHREQNVC VMNPDLTGQT MGKPLNPISS NSPAHQALCS GNPGQDMTLS 430 440 450 460 470 480 SNINFPINGP KEQMGMPMGR FGGSGGMNHV SGMQATTPQG SNYALKMNSP SQSSPGMNPG 490 500 510 520 530 540 QPTSMLSPRH RMSPGVAGSP RIPPSQFSPA GSLHSPVGVC SSTGNSHSYT NSSLNALQAL 550 560 570 580 590 600 SEGHGVSLGS SLASPDLKMG NLQNSPVNMN PPPLSKMGSL DSKDCFGLYG EPSEGTTGQA 610 620 630 640 650 660 ESSCHPGEQK ETNDPNLPPA VSSERADGQS RLHDSKGQTK LLQLLTTKSD QMEPSPLASS 670 680 690 700 710 720 LSDTNKDSTG SLPGSGSTHG TSLKEKHKIL HRLLQDSSSP VDLAKLTAEA TGKDLSQESS 730 740 750 760 770 780 STAPGSEVTI KQEPVSPKKK ENALLRYLLD KDDTKDIGLP EITPKLERLD SKTDPASNTK 790 800 810 820 830 840 LIAMKTEKEE MSFEPGDQPG SELDNLEEIL DDLQNSQLPQ LFPDTRPGAP AGSVDKQAII 850 860 870 880 890 900 NDLMQLTAEN SPVTPVGAQK TALRISQSTF NNPRPGQLGR LLPNQNLPLD ITLQSPTGAG 910 920 930 940 950 960 PFPPIRNSSP YSVIPQPGMM GNQGMIGNQG NLGNSSTGMI GNSASRPTMP SGEWAPQSSA 970 980 990 1000 1010 1020 VRVTCAATTS AMNRPVQGGM IRNPAASIPM RPSSQPGQRQ TLQSQVMNIG PSELEMNMGG 1030 1040 1050 1060 1070 1080 PQYSQQQAPP NQTAPWPESI LPIDQASFAS QNRQPFGSSP DDLLCPHPAA ESPSDEGALL 1090 1100 1110 1120 1130 1140 DQLYLALRNF DGLEEIDRAL GIPELVSQSQ AVDPEQFSSQ DSNIMLEQKA PVFPQQYASQ 1150 1160 1170 1180 1190 1200 AQMAQGSYSP MQDPNFHTMG QRPSYATLRM QPRPGLRPTG LVQNQPNQLR LQLQHRLQAQ 1210 1220 1230 1240 1250 1260 QNRQPLMNQI SNVSNVNLTL RPGVPTQAPI NAQMLAQRQR EILNQHLRQR QMHQQQQVQQ 1270 1280 1290 1300 1310 1320 RTLMMRGQGL NMTPSMVAPS GIPATMSNPR IPQANAQQFP FPPNYGISQQ PDPGFTGATT 1330 1340 1350 1360 1370 1380 PQSPLMSPRM AHTQSPMMQQ SQANPAYQAP SDINGWAQGN MGGNSMFSQQ SPPHFGQQAN 1390 1400 1410 1420 1430 1440 TSMYSNNMNI NVSMATNTGG MSSMNQMTGQ ISMTSVTSVP TSGLSSMGPE QVNDPALRGG 1450 1460 NLFPNQLPGM DMIKQEGDTT RKYC

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI14384.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC114383 mRNA. Translation: AAI14384.1.
UniGene	Hs.446678
3D structure databases
SMR	Q14CD2. Positions 1071-1115.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000140396. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:7669. NCOA2.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q14CD2.
Gene expression databases
ArrayExpress	Q14CD2.
Family and domain databases
InterPro	IPR010011. DUF1518. IPR002048. EF_hand_Ca_bd. IPR001092. HLH_basic. IPR014920. Nuc_rcpt_coact_Ncoa-typ. IPR017426. Nuclear_rcpt_coactivator. IPR001610. PAC. IPR000014. PAS. IPR013767. PAS_fold. IPR014935. SRC-1. [Graphical view]
Pfam	PF07469. DUF1518. 1 hit. PF08815. Nuc_rec_co-act. 1 hit. PF00989. PAS. 1 hit. PF08832. SRC-1. 1 hit. [Graphical view]
PIRSF	PIRSF038181. Nuclear_receptor_coactivator. 1 hit.
SMART	SM00353. HLH. 1 hit. SM00086. PAC. 1 hit. SM00091. PAS. 1 hit. [Graphical view]
PROSITE	PS00018. EF_HAND_1. 1 hit. Uncertain. PS50888. HLH. 1 hit. PS50112. PAS. 1 hit. [Graphical view]

Entry information

Entry name

Q14CD2_HUMAN

Accession

Primary (citable) accession number: Q14CD2

Entry history

Integrated into UniProtKB/TrEMBL:	August 22, 2006
Last sequence update:	August 22, 2006
Last modified:	July 22, 2008
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)