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Protein
Submitted name:

Calcium channel, voltage-dependent, gamma subunit 6

Gene

Cacng6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Thought to stabilize the calcium channel in an inactivated (closed) state.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCalcium channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotation
Biological processCalcium transport, Ion transport, Transport
LigandCalcium

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium channel, voltage-dependent, gamma subunit 6Imported
Gene namesi
Name:Cacng6Imported
ORF Names:mCG_118262Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1859168 Cacng6

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei41 – 63HelicalUniRule annotationAdd BLAST23
Transmembranei139 – 163HelicalUniRule annotationAdd BLAST25
Transmembranei170 – 189HelicalUniRule annotationAdd BLAST20
Transmembranei217 – 241HelicalUniRule annotationAdd BLAST25

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000078815
ExpressionAtlasiQ14C42 baseline and differential

Interactioni

Subunit structurei

The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IWHM Eukaryota
ENOG4111I1Z LUCA
HOVERGENiHBG003868
KOiK04871
OMAiGEANCTY
OrthoDBiEOG091G0HUO

Family and domain databases

InterProiView protein in InterPro
IPR004031 PMP22/EMP/MP20/Claudin
IPR008370 VDCC_g6su
IPR008368 VDCC_gsu
PfamiView protein in Pfam
PF13903 Claudin_2, 1 hit
PRINTSiPR01792 VDCCGAMMA
PR01794 VDCCGAMMA6

Sequencei

Sequence statusi: Complete.

Q14C42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMWSNFFMQE EDRRRTAVGR RRAQEQQNLG LTPEREGKIK LGLLVAIVGA
60 70 80 90 100
TLAVLAVGTE FWVELNTYKT NGSAVCEAAH LGLWKVCIKR LWQADVPAGR
110 120 130 140 150
ETCGPAELPG EANCTYFKFF TTGENARIFQ RTTKKEVNLA AAVIAVLGLT
160 170 180 190 200
AMALGCLCVI MVLSKGAESL LRLGAVCFGL SGLLLFVSLE VFRHSVGALL
210 220 230 240 250
QGVNPETPPA PRLAYEYSWS LGCGVGAGLI LLLGGVCFLL LTLPSWPWRS
260
LCPKWGGPTA
Length:260
Mass (Da):28,145
Last modified:August 22, 2006 - v1
Checksum:i583C326BE6D88C80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC115457 mRNA Translation: AAI15458.1
CH466627 Genomic DNA Translation: EDL31180.1
RefSeqiNP_573446.1, NM_133183.2
UniGeneiMm.424047
Mm.463590

Genome annotation databases

GeneIDi54378
KEGGimmu:54378

Similar proteinsi

Entry informationi

Entry nameiQ14C42_MOUSE
AccessioniPrimary (citable) accession number: Q14C42
Entry historyiIntegrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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