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Q14BV5 (Q14BV5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Aqp6 protein EMBL AAI15587.1
Submitted name:
Aquaporin 6 EMBL ABE96960.1
Gene names
Name:Aqp6 EMBL EDL04122.1 MGI 1341204
Synonyms:AQP6 EMBL ABH01263.1
ORF Names:mCG_20140 EMBL EDL04122.1
OrganismMus musculus (Mouse) EMBL AAI15587.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the MIP/aquaporin family. RuleBase RU000477

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentMembrane
   DomainTransmembrane
   Molecular functionPorin EMBL EDL04122.1
Gene Ontology (GO)
   Biological processwater transport

Inferred from electronic annotation. Source: InterPro

   Cellular componentpore complex

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionporin activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q14BV5 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 2438678E3740E784

FASTA27628,849
        10         20         30         40         50         60 
MEPGLCSRAY LLVGGLWTAI SKALFAEFLA TGLYVFFGVG SVLPWPVALP SVLQIAITFN 

        70         80         90        100        110        120 
LATATAVQIS WKTSGAHANP AVTLAYLVGS HISLPRAMAY IAAQLAGATA GAALLYGVTP 

       130        140        150        160        170        180 
GGIRETLGVN VVHNSTSTGQ AVAVELVLTL QLVLCVFASM DGRQTLASPA AMIGTSVALG 

       190        200        210        220        230        240 
HLIGIYFTGC SMNPARSFGP AVIVGKFAVH WIFWVGPLTG AVLASLIYNF ILFPDTKTVA 

       250        260        270 
QRLAILVGTT KVEKVVDLEP QKKESQTNSE DTEVSV

« Hide

References

« Hide 'large scale' references
[1]"Distal renal tubular acidosis in mice lacking the AE1 (band3) Cl-/HCO3- exchanger (slc4a1)."
Stehberger P.A., Shmukler B.E., Stuart-Tilley A.K., Peters L.L., Alper S.L., Wagner C.A.
J. Am. Soc. Nephrol. 18:1408-1418(2007) [PubMed: 17409310] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J x 129/Sv EMBL ABE96960.1.
Tissue: Kidney EMBL ABE96960.1.
[2]"Molecular cloning and characterization of mouse aquaporin 6."
Nagase H., Agren J., Saito A., Liu K., Agre P., Hazama A., Yasui M.
Biochem. Biophys. Res. Commun. 352:12-16(2007) [PubMed: 17112474] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6 EMBL ABH01263.1.
[3]"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. expand/collapse author list , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
Science 296:1661-1671(2002) [PubMed: 12040188] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL04122.1.
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: PCR rescued clones EMBL AAI15587.1.
[5]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL04122.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC115586 mRNA. Translation: AAI15587.1.
DQ464060 mRNA. Translation: ABE96960.1.
DQ826418 mRNA. Translation: ABH01263.1.
CH466550 Genomic DNA. Translation: EDL04122.1.
IPIIPI00225353.
UniGeneMm.202309.

3D structure databases

ProteinModelPortalQ14BV5.
SMRQ14BV5. Positions 20-248.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ14BV5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc007xpv.1. mouse.

Phylogenomic databases

HOVERGENHBG000312.
InParanoidQ14BV5.

Gene expression databases

ArrayExpressQ14BV5.
GenevestigatorQ14BV5.

Family and domain databases

InterProIPR012269. Aquaporin.
IPR023271. Aquaporin-like.
IPR023254. Aquaporin_6.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
Gene3DG3DSA:1.20.1080.10. MIP. 1 hit.
PANTHERPTHR19139:SF36. Aquaporin_6. 1 hit.
PTHR19139. MIP. 1 hit.
PfamPF00230. MIP. 1 hit.
[Graphical view]
PRINTSPR02018. AQUAPORIN6.
PR00783. MINTRINSICP.
SUPFAMSSF81338. MIP. 1 hit.
TIGRFAMsTIGR00861. MIP. 1 hit.
PROSITEPS00221. MIP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ14BV5_MOUSE
AccessionPrimary (citable) accession number: Q14BV5
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: November 16, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info