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Protein
Submitted name:

Alpha-1,4-N-acetylglucosaminyltransferase

Gene

A4gnt

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • acetylglucosaminyltransferase activity Source: MGI

GO - Biological processi

  • glycoprotein biosynthetic process Source: MGI
  • negative regulation of epithelial cell proliferation Source: MGI
  • protein O-linked glycosylation Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseImported, Transferase

Enzyme and pathway databases

ReactomeiR-MMU-913709. O-linked glycosylation of mucins.

Protein family/group databases

CAZyiGT32. Glycosyltransferase Family 32.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-1,4-N-acetylglucosaminyltransferaseImported
Submitted name:
MCG18102Imported
Submitted name:
Protein A4gntImported
Gene namesi
Name:A4gntImported
ORF Names:mCG_18102Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2143261. A4gnt.

PTM / Processingi

PTM databases

PhosphoSiteiQ14BT6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000037953.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045629.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini198 – 322125Gb3_synthInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1928. Eukaryota.
ENOG4111PD8. LUCA.
GeneTreeiENSGT00510000047981.
HOGENOMiHOG000254772.
HOVERGENiHBG106704.
KOiK08251.
OMAiFLNPQRF.
OrthoDBiEOG091G08S2.
TreeFamiTF324053.

Family and domain databases

InterProiIPR007652. A1-4-GlycosylTfrase_dom.
IPR007577. GlycoTrfase_DXD_sugar-bd_CS.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF04572. Gb3_synth. 1 hit.
PF04488. Gly_transf_sug. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

Q14BT6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKEIYLSLS LVLVFACGLL YQLTMRSQCF FACLPPFSFP QGLDGLLRSG
60 70 80 90 100
RSIMFIETSE RVEPPPMVSC AVESAAKIYP EQPIIFFMKG LRDSVQLTSN
110 120 130 140 150
TSYPAFSLLS AINNVFFVPL DMERLFKDTP LFSWYTKVNS STEKHWLHVS
160 170 180 190 200
SDAARLAIIW KYGGIYMDTD VISLQPIPEE NFLAAQGSRH SSNGVFGFLP
210 220 230 240 250
HHPFLWACME NFVEHYDSTI WGNQGPQLMT RMLRVWCRLK DFHGLGDLKC
260 270 280 290 300
LNISFLHPQR FYPIPYPQWK RYYQVWDKEP SFNESYALHL WNYMNKEGKT
310 320 330 340
VVRGSKTLVE NLYQKHCPKT YRVLIQGAEG TVSKKPGTGS R
Length:341
Mass (Da):39,276
Last modified:August 22, 2006 - v1
Checksum:i17733C8FAFC37A44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC156497 Genomic DNA. No translation available.
AC157949 Genomic DNA. No translation available.
BC115614 mRNA. Translation: AAI15615.1.
BC115615 mRNA. Translation: AAI15616.1.
CH466560 Genomic DNA. Translation: EDL21015.1.
RefSeqiNP_001070892.1. NM_001077424.2.
XP_006511307.2. XM_006511244.2.
XP_006511308.1. XM_006511245.2.
XP_006511309.1. XM_006511246.2.
UniGeneiMm.297753.

Genome annotation databases

EnsembliENSMUST00000042553; ENSMUSP00000045629; ENSMUSG00000037953.
GeneIDi333424.
KEGGimmu:333424.
UCSCiuc009rej.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC156497 Genomic DNA. No translation available.
AC157949 Genomic DNA. No translation available.
BC115614 mRNA. Translation: AAI15615.1.
BC115615 mRNA. Translation: AAI15616.1.
CH466560 Genomic DNA. Translation: EDL21015.1.
RefSeqiNP_001070892.1. NM_001077424.2.
XP_006511307.2. XM_006511244.2.
XP_006511308.1. XM_006511245.2.
XP_006511309.1. XM_006511246.2.
UniGeneiMm.297753.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045629.

Protein family/group databases

CAZyiGT32. Glycosyltransferase Family 32.

PTM databases

PhosphoSiteiQ14BT6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042553; ENSMUSP00000045629; ENSMUSG00000037953.
GeneIDi333424.
KEGGimmu:333424.
UCSCiuc009rej.2. mouse.

Organism-specific databases

CTDi51146.
MGIiMGI:2143261. A4gnt.

Phylogenomic databases

eggNOGiKOG1928. Eukaryota.
ENOG4111PD8. LUCA.
GeneTreeiENSGT00510000047981.
HOGENOMiHOG000254772.
HOVERGENiHBG106704.
KOiK08251.
OMAiFLNPQRF.
OrthoDBiEOG091G08S2.
TreeFamiTF324053.

Enzyme and pathway databases

ReactomeiR-MMU-913709. O-linked glycosylation of mucins.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000037953.

Family and domain databases

InterProiIPR007652. A1-4-GlycosylTfrase_dom.
IPR007577. GlycoTrfase_DXD_sugar-bd_CS.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF04572. Gb3_synth. 1 hit.
PF04488. Gly_transf_sug. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ14BT6_MOUSE
AccessioniPrimary (citable) accession number: Q14BT6
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: September 7, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.