Q14AD9 (Q14AD9_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Colony stimulating factor 2 (Granulocyte-macrophage) EMBL AAI16881.1

Gene names

Name:

Csf2 MGI 1339752

Organism

Mus musculus (Mouse) EMBL AAI16881.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	141 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	embryonic placenta development Inferred from mutant phenotype PubMed 19228596. Source: MGI immune response Inferred from electronic annotation. Source: InterPro myeloid dendritic cell differentiation Inferred from direct assay PubMed 12021780. Source: MGI positive regulation of cell proliferation Inferred from direct assay PubMed 10652277PubMed 1350248. Source: MGI regulation of gene expression Inferred from direct assay PubMed 9697835. Source: MGI
Cellular_component	extracellular space Inferred from direct assay PubMed 7690439. Source: MGI
Molecular_function	cytokine activity Inferred from direct assay PubMed 10652277PubMed 1350248. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q14AD9 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 209C660B4FF77349	FASTA	141	16,133
	10 20 30 40 50 60 MWLQNLLFLG IVVYSLSAPT RSPITVTRPW KHVEAIKEAL NLLDDMPVTL NEEVEVVSNE 70 80 90 100 110 120 FSFKKLTCVQ TRLKIFEQGL RGNFTKLKGA LNMTASYYQT YCPPTPETDC ETQVTTYADF 130 140 IDSLKTFLTD IPFECKKPVQ K

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAI16881.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC116878 mRNA. Translation: AAI16879.1. BC116880 mRNA. Translation: AAI16881.1.
IPI	IPI00323907.
UniGene	Mm.4922.
3D structure databases
SMR	Q14AD9. Positions 22-138.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:1339752. Csf2.
Phylogenomic databases
HOVERGEN	HBG000532.
InParanoid	Q14AD9.
Gene expression databases
Genevestigator	Q14AD9.
Family and domain databases
Gene3D	1.20.1250.10. 1 hit.
InterPro	IPR009079. 4_helix_cytokine-like_core. IPR012351. 4_helix_cytokine_core. IPR000773. GM_colony-stim-fac. [Graphical view]
PANTHER	PTHR10059. PTHR10059. 1 hit.
Pfam	PF01109. GM_CSF. 1 hit. [Graphical view]
PRINTS	PR00693. GMCSFACTOR.
ProDom	PD007349. GM_colony-stim-fac. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00040. CSF2. 1 hit. [Graphical view]
SUPFAM	SSF47266. 4_helix_cytokine. 1 hit.
PROSITE	PS00702. GM_CSF. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	CSF2. mouse.
SOURCE	Search...

Entry information

Entry name

Q14AD9_MOUSE

Accession

Primary (citable) accession number: Q14AD9

Entry history

Integrated into UniProtKB/TrEMBL:	August 22, 2006
Last sequence update:	August 22, 2006
Last modified:	April 3, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)