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Protein
Submitted name:

Melatonin receptor 1A

Gene

Mtnr1a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Melatonin receptor 1AImported
Gene namesi
Name:Mtnr1aImported
ORF Names:mCG_20978Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:102967. Mtnr1a.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 55HelicalSequence analysisAdd BLAST23
Transmembranei67 – 85HelicalSequence analysisAdd BLAST19
Transmembranei105 – 126HelicalSequence analysisAdd BLAST22
Transmembranei147 – 166HelicalSequence analysisAdd BLAST20
Transmembranei192 – 218HelicalSequence analysisAdd BLAST27
Transmembranei239 – 266HelicalSequence analysisAdd BLAST28
Transmembranei278 – 301HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000054764.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069872.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 298G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST252

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHFY. Eukaryota.
ENOG4111ZZV. LUCA.
HOVERGENiHBG052528.
KOiK04285.
OMAiHFLVPMI.
OrthoDBiEOG091G0GO0.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002278. Mel_1A_rcpt.
IPR000025. Melatonin_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01149. MELATONIN1AR.
PR00857. MELATONINR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q14AC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGNVSELLN ATQQAPGGGE GGRPRPSWLA STLAFILIFT IVVDILGNLL
60 70 80 90 100
VILSVYRNKK LRNSGNIFVV SLAVADLVVA VYPYPLVLTS ILNNGWNLGY
110 120 130 140 150
LHCQVSAFLM GLSVIGSIFN ITGIAMNRYC YICHSLKYDK IYSNKNSLCY
160 170 180 190 200
VFLIWMLTLI AIMPNLQTGT LQYDPRIYSC TFTQSVSSAY TIAVVVFHFI
210 220 230 240 250
VPMIIVIFCY LRIWVLVLQV RRRVKPDNKP KLKPQDFRNF VTMFVVFVLF
260 270 280 290 300
AICWAPLNLI GLIVASDPAT MVPRIPEWLF VASYYLAYFN SCLNAIIYGL
310 320 330 340 350
LNQNFRKEYK KIIVSLCTAK MFFVESSNEE ADKIKCKPSP LIPNNNLIKV

DSV
Length:353
Mass (Da):39,837
Last modified:August 22, 2006 - v1
Checksum:i0975C2FD41B54C74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116900 mRNA. Translation: AAI16901.1.
BC119313 mRNA. Translation: AAI19314.1.
CH466554 Genomic DNA. Translation: EDL35540.1.
RefSeqiNP_032665.1. NM_008639.2.
UniGeneiMm.5133.

Genome annotation databases

GeneIDi17773.
KEGGimmu:17773.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116900 mRNA. Translation: AAI16901.1.
BC119313 mRNA. Translation: AAI19314.1.
CH466554 Genomic DNA. Translation: EDL35540.1.
RefSeqiNP_032665.1. NM_008639.2.
UniGeneiMm.5133.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069872.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi17773.
KEGGimmu:17773.

Organism-specific databases

CTDi4543.
MGIiMGI:102967. Mtnr1a.

Phylogenomic databases

eggNOGiENOG410IHFY. Eukaryota.
ENOG4111ZZV. LUCA.
HOVERGENiHBG052528.
KOiK04285.
OMAiHFLVPMI.
OrthoDBiEOG091G0GO0.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000054764.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002278. Mel_1A_rcpt.
IPR000025. Melatonin_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01149. MELATONIN1AR.
PR00857. MELATONINR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ14AC3_MOUSE
AccessioniPrimary (citable) accession number: Q14AC3
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: November 30, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.