SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q148R4

- Q148R4_MOUSE

UniProt

Q148R4 - Q148R4_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Protein Spink5

Gene
Spink5
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. peptidase inhibitor activity Source: MGI
  2. serine-type endopeptidase inhibitor activity Source: Ensembl

GO - Biological processi

  1. epidermal cell differentiation Source: Ensembl
  2. negative regulation of proteolysis Source: MGI
  3. negative regulation of serine-type peptidase activity Source: MGI
  4. regulation of cell adhesion Source: MGI
Complete GO annotation...

Protein family/group databases

MEROPSiI01.958.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Spink5Imported
Submitted name:
Serine peptidase inhibitor, Kazal type 5Imported
Gene namesi
Name:Spink5Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 18

Organism-specific databases

MGIiMGI:1919682. Spink5.

Subcellular locationi

GO - Cellular componenti

  1. cell cortex Source: Ensembl
  2. cytosol Source: Ensembl
  3. endoplasmic reticulum membrane Source: Ensembl
  4. epidermal lamellar body Source: Ensembl
  5. perinuclear region of cytoplasm Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ148R4.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG253835.
GeneTreeiENSGT00510000048608.
HOGENOMiHOG000015390.
HOVERGENiHBG006183.
InParanoidiQ148R4.
OMAiCHENLIR.
OrthoDBiEOG7BW0M2.
TreeFamiTF336724.

Family and domain databases

InterProiIPR002350. Kazal_dom.
[Graphical view]
PfamiPF00050. Kazal_1. 2 hits.
PF07648. Kazal_2. 11 hits.
[Graphical view]
SMARTiSM00280. KAZAL. 13 hits.
[Graphical view]
PROSITEiPS00282. KAZAL_1. 2 hits.
PS51465. KAZAL_2. 13 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q148R4-1 [UniParc]FASTAAdd to Basket

« Hide

MKTATVPMLL TLAFYLTQDA AGEKGNQDPC MKFQAQMKNG TLTCPKGNNS     50
SQSLNDIIFQ SECILCKRAL EQGAPTKIMN VKVLSRANRA TDPAKLNCES 100
FKQRRKDGDF ICPSDTSSVC GTDGKTYRSR CELCAENAKS QNHVDVKSEG 150
ECGSSHLETD MCSDFRAYVQ DGRLGCTRES DPILGPDGRT HGNRCAMCAE 200
LFLKEAKENA TRNRESRIRR DAEKELCKEF ENQVRNGRLF CTRESDPIRG 250
PDGKMHGNKC ALCAEIFMRQ FTEEKGKAEK NQKDAEERAK AKMEIQKRCS 300
EFQDRARNGT LFCTRENDPI RGLDGKTHGN LCSMCQAFFK TEAEEKKAEA 350
GSRNRRGSEE SETYAKLCDE YRKARKNGQL YCTRENAPIR GPDGKIHGNT 400
CSMCQAFFIQ EDKARAKVKR EAAKEMCSEF RNQARNGMLM CTRENDPVVG 450
PDGKRHSNKC AMCASVFLLE EEEKKKDDKT EKVDAGKAKK EAVQELCRKY 500
HTQLRNGPLR CTRRNNPIEG LDGKMYKNAC FMCWAFFQQE AKKSGAGFRP 550
KVKREVKVDC SEYLALSKRG EIFCTRENDP VRGPDGKTHG NKCAMCKAVF 600
KKENEERKRK EGENQRITSG ESSSGGNPKA KDECAQYRES MKHGQLSCTR 650
ESDPVRGVDG EHYNNKCVMC KELLQKEMEE TNKNSASRSN GTGSATGKDV 700
CDQFRSQMKN GKLLCTRESD PTRGPDGAMH GNKCAMCKER LEKEAAEKKK 750
KEDEEKRNTE TNKSDKEDKC HEYRSMQLDG RLICTRENDP VRDADGKMHV 800
NKCAMCQMMF EREANERKMR EENSRSQPTN EAKDQCGEVH NSVEDAKPRP 850
ARSSLPSIRG ISKDECSEFQ NLMKNEKLTC PETDDPVRGA DGTFYQNKCH 900
MCRDVLKNEA MKRSGLQEKS SDIRSTKEGD PEFSSSSRDS DMCKNYRILP 950
RMGYLCPKNL NPVCGDDGQT YSNPCMLCHE NLMRQTNTRI HKQGACEESS 1000
NLKTVSTGTP ASEKMMQ 1017
Length:1,017
Mass (Da):114,891
Last modified:August 22, 2006 - v1
Checksum:iFE32F4B2D9A4BB66
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC138293 Genomic DNA. No translation available.
BC118011 mRNA. Translation: AAI18012.1.
RefSeqiNP_001074649.1. NM_001081180.1.
XP_006526342.1. XM_006526279.1.
XP_006526343.1. XM_006526280.1.
UniGeneiMm.35369.

Genome annotation databases

EnsembliENSMUST00000069245; ENSMUSP00000066214; ENSMUSG00000055561.
GeneIDi72432.
KEGGimmu:72432.
UCSCiuc008eup.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC138293 Genomic DNA. No translation available.
BC118011 mRNA. Translation: AAI18012.1 .
RefSeqi NP_001074649.1. NM_001081180.1.
XP_006526342.1. XM_006526279.1.
XP_006526343.1. XM_006526280.1.
UniGenei Mm.35369.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I01.958.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000069245 ; ENSMUSP00000066214 ; ENSMUSG00000055561 .
GeneIDi 72432.
KEGGi mmu:72432.
UCSCi uc008eup.1. mouse.

Organism-specific databases

CTDi 11005.
MGIi MGI:1919682. Spink5.

Phylogenomic databases

eggNOGi NOG253835.
GeneTreei ENSGT00510000048608.
HOGENOMi HOG000015390.
HOVERGENi HBG006183.
InParanoidi Q148R4.
OMAi CHENLIR.
OrthoDBi EOG7BW0M2.
TreeFami TF336724.

Miscellaneous databases

NextBioi 336242.
PROi Q148R4.
SOURCEi Search...

Gene expression databases

Genevestigatori Q148R4.

Family and domain databases

InterProi IPR002350. Kazal_dom.
[Graphical view ]
Pfami PF00050. Kazal_1. 2 hits.
PF07648. Kazal_2. 11 hits.
[Graphical view ]
SMARTi SM00280. KAZAL. 13 hits.
[Graphical view ]
PROSITEi PS00282. KAZAL_1. 2 hits.
PS51465. KAZAL_2. 13 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ148R4_MOUSE
AccessioniPrimary (citable) accession number: Q148R4
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi