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Protein
Submitted name:

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

Gene

St8sia6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseSAAS annotationImported, Transferase

Protein family/group databases

CAZyiGT29. Glycosyltransferase Family 29.

Names & Taxonomyi

Protein namesi
Submitted name:
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6Imported
Submitted name:
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6, isoform CRA_bImported
Gene namesi
Name:St8sia6Imported
ORF Names:mCG_113994Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2386797. St8sia6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatusSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929Sequence analysisAdd
BLAST
Chaini30 – 398369Sequence analysisPRO_5007922982Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi186 ↔ 335UniRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000003418.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003509.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG2692. Eukaryota.
ENOG410XT8P. LUCA.
HOVERGENiHBG106106.
KOiK06615.
OMAiNMSYEVE.
OrthoDBiEOG091G0CER.

Family and domain databases

InterProiIPR001675. Glyco_trans_29.
IPR012163. Sialyl_trans.
[Graphical view]
PfamiPF00777. Glyco_transf_29. 1 hit.
[Graphical view]
PIRSFiPIRSF005557. Sialyl_trans. 1 hit.

Sequencei

Sequence statusi: Complete.

Q148N5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSGGTLFAL IGSLMLLLLL RMLWCPADAP ARSRLLMEGS REDTSGTSAA
60 70 80 90 100
LKTLWSPTTP VPRTRNSTYL DEKTTQITEK CKDLQYSLNS LSNKTRRYSE
110 120 130 140 150
DDYLQTITNI QRCPWNRQAE EYDNFRAKLA SCCDAIQDFV VSQNNTPVGT
160 170 180 190 200
NMSYEVESKK HIPIRENIFH MFPVSQPFVD YPYNQCAVVG NGGILNKSLC
210 220 230 240 250
GAEIDKSDFV FRCNLPPITG SASKDVGSKT NLVTVNPSII TLKYQNLKEK
260 270 280 290 300
KAQFLEDIST YGDAFLLLPA FSYRANTGIS FKVYQTLKES KMRQKVLFFH
310 320 330 340 350
PRYLRHLALF WRTKGVTAYR LSTGLMIASV AVELCENVKL YGFWPFSKTI
360 370 380 390
EDTPLSHHYY DNMLPKHGFH QMPKEYSQML QLHMRGILKL QFSKCETA
Length:398
Mass (Da):45,428
Last modified:August 22, 2006 - v1
Checksum:iA73A7A29640D4917
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC115912 mRNA. Translation: AAI15913.1.
BC118063 mRNA. Translation: AAI18064.1.
CH466542 Genomic DNA. Translation: EDL08056.1.
RefSeqiNP_665837.1. NM_145838.1.
UniGeneiMm.330004.
Mm.393036.

Genome annotation databases

GeneIDi241230.
KEGGimmu:241230.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC115912 mRNA. Translation: AAI15913.1.
BC118063 mRNA. Translation: AAI18064.1.
CH466542 Genomic DNA. Translation: EDL08056.1.
RefSeqiNP_665837.1. NM_145838.1.
UniGeneiMm.330004.
Mm.393036.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003509.

Protein family/group databases

CAZyiGT29. Glycosyltransferase Family 29.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi241230.
KEGGimmu:241230.

Organism-specific databases

CTDi338596.
MGIiMGI:2386797. St8sia6.

Phylogenomic databases

eggNOGiKOG2692. Eukaryota.
ENOG410XT8P. LUCA.
HOVERGENiHBG106106.
KOiK06615.
OMAiNMSYEVE.
OrthoDBiEOG091G0CER.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000003418.

Family and domain databases

InterProiIPR001675. Glyco_trans_29.
IPR012163. Sialyl_trans.
[Graphical view]
PfamiPF00777. Glyco_transf_29. 1 hit.
[Graphical view]
PIRSFiPIRSF005557. Sialyl_trans. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ148N5_MOUSE
AccessioniPrimary (citable) accession number: Q148N5
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: September 7, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.