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Protein
Submitted name:

Fumarate hydratase

Gene

FH

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-BTA-71403. Citric acid cycle (TCA cycle).

Names & Taxonomyi

Protein namesi
Submitted name:
Fumarate hydrataseImported
Gene namesi
Name:FHImported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSBTAG00000021688.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000028902.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 389Lyase_1InterPro annotationAdd BLAST332
Domaini455 – 507FumaraseC_CInterPro annotationAdd BLAST53

Phylogenomic databases

eggNOGiKOG1317. Eukaryota.
COG0114. LUCA.
GeneTreeiENSGT00390000002779.
HOGENOMiHOG000061736.
HOVERGENiHBG002183.
KOiK01679.
OMAiVSFTDNC.
OrthoDBiEOG091G05UL.
TreeFamiTF300441.

Family and domain databases

CDDicd01362. Fumarase_classII. 1 hit.
Gene3Di1.10.275.10. 1 hit.
HAMAPiMF_00743. FumaraseC. 1 hit.
InterProiView protein in InterPro
IPR005677. Fum_hydII.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiView protein in Pfam
PF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00979. fumC_II. 1 hit.
PROSITEiView protein in PROSITE
PS00163. FUMARATE_LYASES. 1 hit.

Sequencei

Sequence statusi: Complete.

Q148D3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRALRLLAR SRLLSRNPGS APKPGLGPGG PAVLLLRPPN AARMASQNSF
60 70 80 90 100
RIEYDTFGEL KVPNDKYYGA QTVRSTMNFK IGGMTERMPI PVIKAFGILK
110 120 130 140 150
RAAAEVNQDY GLDPKIANAI MKAADEVAEG KLNDHFPLVV WQTGSGTQTN
160 170 180 190 200
MNVNEVISNR AIEILGGELG SKKPVHPNDH VNKSQSSNDT FPTAMHIAAA
210 220 230 240 250
IEVHEVLLPG LQKLHDALEA KSKEFDQIIK IGRTHTQDAV PLTLGQEFSG
260 270 280 290 300
YVQQVKYATT RIKAAMPRIY ELAAGGTAVG TGLNTRIGFA EKVAAKVAVL
310 320 330 340 350
TGLPFVTAPN KFEALAAHDA LVELSGAMNT TACSLMKIAN DIRFLGSGPR
360 370 380 390 400
SGLGELILPE NEPGSSIMPG KVNPTQCEAM TMVAAQVMGN HVAVTVGGSN
410 420 430 440 450
GHFELNVFKP MMIKNVLHSA RLLGDASVSF TENCVVGIQA NTERISKLMN
460 470 480 490 500
ESLMLVTALN PHIGYDKAAK IAKTAHKNGS TLKATAIELG YLTAEQFDEW
510
VKPKDMLGPK
Length:510
Mass (Da):54,691
Last modified:August 22, 2006 - v1
Checksum:iFF5AD14825691745
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02042810 Genomic DNA. No translation available.
BC118450 mRNA. Translation: AAI18451.1.
RefSeqiNP_001069271.1. NM_001075803.2.
UniGeneiBt.45986.

Genome annotation databases

EnsembliENSBTAT00000028902; ENSBTAP00000028902; ENSBTAG00000021688.
GeneIDi520260.
KEGGibta:520260.

Similar proteinsi

Entry informationi

Entry nameiQ148D3_BOVIN
AccessioniPrimary (citable) accession number: Q148D3
Entry historyiIntegrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: August 30, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported