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Protein
Submitted name:

PTGER3 protein

Gene

PTGER3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PTGER3 proteinImported
Gene namesi
Name:PTGER3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei52 – 75HelicalSequence analysisAdd BLAST24
Transmembranei87 – 112HelicalSequence analysisAdd BLAST26
Transmembranei132 – 153HelicalSequence analysisAdd BLAST22
Transmembranei173 – 194HelicalSequence analysisAdd BLAST22
Transmembranei228 – 253HelicalSequence analysisAdd BLAST26
Transmembranei284 – 307HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ147X8.

Expressioni

Gene expression databases

BgeeiENSG00000050628.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
ADAMTSL4Q6UY14-33EBI-10234038,EBI-10173507
CDAP323203EBI-10234038,EBI-9250559
EFEMP2O959673EBI-10234038,EBI-743414
INCA1Q0VD863EBI-10234038,EBI-6509505
KRT31Q153235EBI-10234038,EBI-948001
KRT38O760153EBI-10234038,EBI-1047263
KRT40Q6A1623EBI-10234038,EBI-10171697
KRTAP10-7P604093EBI-10234038,EBI-10172290
KRTAP10-8P604103EBI-10234038,EBI-10171774
KRTAP10-9P604113EBI-10234038,EBI-10172052
MEOX2A4D1273EBI-10234038,EBI-10172134
NOTCH2NLQ7Z3S93EBI-10234038,EBI-945833
RELQ048643EBI-10234038,EBI-307352
RGS17Q9UGC63EBI-10234038,EBI-3918154
RGS20O760813EBI-10234038,EBI-1052678
RGS20O76081-63EBI-10234038,EBI-10178530
SPRY2O435973EBI-10234038,EBI-742487
TCF4P158843EBI-10234038,EBI-533224
TRIM42A1L4B63EBI-10234038,EBI-10172216

Protein-protein interaction databases

IntActiQ147X8. 21 interactors.
STRINGi9606.ENSP00000349003.

Structurei

3D structure databases

ProteinModelPortaliQ147X8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 346G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST282

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000015238.
HOVERGENiHBG052720.

Family and domain databases

InterProiIPR001481. EP3_rcpt_2.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR008365. Prostanoid_rcpt.
IPR001244. Prostglndn_DP_rcpt.
IPR000265. Prostglndn_EP3_rcpt.
[Graphical view]
PANTHERiPTHR11866. PTHR11866. 1 hit.
PTHR11866:SF10. PTHR11866:SF10. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00428. PROSTAGLNDNR.
PR01788. PROSTANOIDR.
PR00584. PRSTNOIDE32R.
PR00582. PRSTNOIDEP3R.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q147X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKETRGYGGD APFCTRLNHS YTGMWAPERS AEARGNLTRP PGSGEDCGSV
60 70 80 90 100
SVAFPITMLL TGFVGNALAM LLVSRSYRRR ESKRKKSFLL CIGWLALTDL
110 120 130 140 150
VGQLLTTPVV IVVYLSKQRW EHIDPSGRLC TFFGLTMTVF GLSSLFIASA
160 170 180 190 200
MAVERALAIR APHWYASHMK TRATRAVLLG VWLAVLAFAL LPVLGVGQYT
210 220 230 240 250
VQWPGTWCFI STGRGGNGTS SSHNWGNLFF ASAFAFLGLL ALTVTFSCNL
260 270 280 290 300
ATIKALVSRC RAKATASQSS AQWGRITTET AIQLMGIMCV LSVCWSPLLI
310 320 330 340 350
MMLKMIFNQT SVEHCKTHTE KQKECNFFLI AVRLASLNQI LDPWVYLLLR
360 370 380 390 400
KILLRKFCQM RKRRLREQFW RPASSGSGCQ QIRCLMESCS LTQTGVQWSD
410 420
FRSLQPSPPP LTAIFASWVQ VILLPQPPK
Length:429
Mass (Da):47,736
Last modified:August 22, 2006 - v1
Checksum:i1CC39D17C3FE5FF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC118578 mRNA. Translation: AAI18579.1.
UniGeneiHs.445000.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC118578 mRNA. Translation: AAI18579.1.
UniGeneiHs.445000.

3D structure databases

ProteinModelPortaliQ147X8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ147X8. 21 interactors.
STRINGi9606.ENSP00000349003.

Proteomic databases

PaxDbiQ147X8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000015238.
HOVERGENiHBG052720.

Miscellaneous databases

ChiTaRSiPTGER3. human.

Gene expression databases

BgeeiENSG00000050628.

Family and domain databases

InterProiIPR001481. EP3_rcpt_2.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR008365. Prostanoid_rcpt.
IPR001244. Prostglndn_DP_rcpt.
IPR000265. Prostglndn_EP3_rcpt.
[Graphical view]
PANTHERiPTHR11866. PTHR11866. 1 hit.
PTHR11866:SF10. PTHR11866:SF10. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00428. PROSTAGLNDNR.
PR01788. PROSTANOIDR.
PR00584. PRSTNOIDE32R.
PR00582. PRSTNOIDEP3R.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ147X8_HUMAN
AccessioniPrimary (citable) accession number: Q147X8
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: November 30, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.