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Q14789 (GOGB1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 123. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Golgin subfamily B member 1
Alternative name(s):
372 kDa Golgi complex-associated protein
Short name=GCP372
Giantin
Macrogolgin
Gene names
Name:GOLGB1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length3259 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May participate in forming intercisternal cross-bridges of the Golgi complex.

Subunit structure

Homodimer; disulfide-linked. Interacts with PLK3. Ref.7

Subcellular location

Golgi apparatus membrane; Single-pass type I membrane protein.

Miscellaneous

Antigen in chronic rheumatoid arthritis and in the autoimmune disease Sjoegren syndrome.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

PFN2P350802EBI-709973,EBI-473138

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q14789-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q14789-2)

The sequence of this isoform differs from the canonical sequence as follows:
     215-215: A → AQLSSM
     3102-3102: A → AVSKEK
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 32593259Golgin subfamily B member 1
PRO_0000190071

Regions

Topological domain1 – 32353235Cytoplasmic Potential
Transmembrane3236 – 325621Helical; Potential
Topological domain3257 – 32593Lumenal Potential
Coiled coil48 – 593546 Potential
Coiled coil677 – 1028352 Potential
Coiled coil1062 – 1245184 Potential
Coiled coil1301 – 1779479 Potential
Coiled coil1828 – 31851358 Potential
Compositional bias2420 – 24234Poly-Glu
Compositional bias2993 – 29964Poly-Ser

Amino acid modifications

Modified residue61Phosphoserine Ref.10
Modified residue171Phosphoserine Ref.8 Ref.10 Ref.11
Modified residue1381Phosphoserine Ref.11

Natural variations

Alternative sequence2151A → AQLSSM in isoform 2.
VSP_045567
Alternative sequence31021A → AVSKEK in isoform 2.
VSP_045568
Natural variant3481Q → H in a breast cancer sample; somatic mutation. Ref.14
VAR_036096
Natural variant9111T → S. Ref.4
Corresponds to variant rs3732407 [ dbSNP | Ensembl ].
VAR_020155
Natural variant9441A → G in a breast cancer sample; somatic mutation. Ref.14
VAR_036097
Natural variant12121Y → C. Ref.4
Corresponds to variant rs3732410 [ dbSNP | Ensembl ].
VAR_020156
Natural variant12491P → S.
Corresponds to variant rs33988592 [ dbSNP | Ensembl ].
VAR_031671
Natural variant17131C → F.
Corresponds to variant rs35674179 [ dbSNP | Ensembl ].
VAR_031672
Natural variant17651G → D. Ref.1 Ref.2 Ref.4
Corresponds to variant rs1127412 [ dbSNP | Ensembl ].
VAR_031673

Experimental info

Sequence conflict1 – 3939Missing in BAA05025. Ref.3
Sequence conflict2151A → AQLSSM in BAA05025. Ref.3
Sequence conflict29501H → D in BAA05025. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified April 17, 2007. Version 2.
Checksum: ED5D043C3A5C6432

FASTA3,259376,019
        10         20         30         40         50         60 
MLSRLSGLAN VVLHELSGDD DTDQNMRAPL DPELHQESDM EFNNTTQEDV QERLAYAEQL 

        70         80         90        100        110        120 
VVELKDIIRQ KDVQLQQKDE ALQEERKAAD NKIKKLKLHA KAKLTSLNKY IEEMKAQGGT 

       130        140        150        160        170        180 
VLPTEPQSEE QLSKHDKSST EEEMEIEKIK HKLQEKEELI STLQAQLTQA QAEQPAQSST 

       190        200        210        220        230        240 
EMEEFVMMKQ QLQEKEEFIS TLQAQLSQTQ AEQAAQQVVR EKDARFETQV RLHEDELLQL 

       250        260        270        280        290        300 
VTQADVETEM QQKLRVLQRK LEEHEESLVG RAQVVDLLQQ ELTAAEQRNQ ILSQQLQQME 

       310        320        330        340        350        360 
AEHNTLRNTV ETEREESKIL LEKMELEVAE RKLSFHNLQE EMHHLLEQFE QAGQAQAELE 

       370        380        390        400        410        420 
SRYSALEQKH KAEMEEKTSH ILSLQKTGQE LQSACDALKD QNSKLLQDKN EQAVQSAQTI 

       430        440        450        460        470        480 
QQLEDQLQQK SKEISQFLNR LPLQQHETAS QTSFPDVYNE GTQAVTEENI ASLQKRVVEL 

       490        500        510        520        530        540 
ENEKGALLLS SIELEELKAE NEKLSSQITL LEAQNRTGEA DREVSEISIV DIANKRSSSA 

       550        560        570        580        590        600 
EESGQDVLEN TFSQKHKELS VLLLEMKEAQ EEIAFLKLQL QGKRAEEADH EVLDQKEMKQ 

       610        620        630        640        650        660 
MEGEGIAPIK MKVFLEDTGQ DFPLMPNEES SLPAVEKEQA STEHQSRTSE EISLNDAGVE 

       670        680        690        700        710        720 
LKSTKQDGDK SLSAVPDIGQ CHQDELERLK SQILELELNF HKAQEIYEKN LDEKAKEISN 

       730        740        750        760        770        780 
LNQLIEEFKK NADNNSSAFT ALSEERDQLL SQVKELSMVT ELRAQVKQLE MNLAEAERQR 

       790        800        810        820        830        840 
RLDYESQTAH DNLLTEQIHS LSIEAKSKDV KIEVLQNELD DVQLQFSEQS TLIRSLQSQL 

       850        860        870        880        890        900 
QNKESEVLEG AERVRHISSK VEELSQALSQ KELEITKMDQ LLLEKKRDVE TLQQTIEEKD 

       910        920        930        940        950        960 
QQVTEISFSM TEKMVQLNEE KFSLGVEIKT LKEQLNLLSR AEEAKKEQVE EDNEVSSGLK 

       970        980        990       1000       1010       1020 
QNYDEMSPAG QISKEELQHE FDLLKKENEQ RKRKLQAALI NRKELLQRVS RLEEELANLK 

      1030       1040       1050       1060       1070       1080 
DESKKEIPLS ETERGEVEED KENKEYSEKC VTSKCQEIEI YLKQTISEKE VELQHIRKDL 

      1090       1100       1110       1120       1130       1140 
EEKLAAEEQF QALVKQMNQT LQDKTNQIDL LQAEISENQA IIQKLITSNT DASDGDSVAL 

      1150       1160       1170       1180       1190       1200 
VKETVVISPP CTGSSEHWKP ELEEKILALE KEKEQLQKKL QEALTSRKAI LKKAQEKERH 

      1210       1220       1230       1240       1250       1260 
LREELKQQKD DYNRLQEQFD EQSKENENIG DQLRQLQIQV RESIDGKLPS TDQQESCSST 

      1270       1280       1290       1300       1310       1320 
PGLEEPLFKA TEQHHTQPVL ESNLCPDWPS HSEDASALQG GTSVAQIKAQ LKEIEAEKVE 

      1330       1340       1350       1360       1370       1380 
LELKVSSTTS ELTKKSEEVF QLQEQINKQG LEIESLKTVS HEAEVHAESL QQKLESSQLQ 

      1390       1400       1410       1420       1430       1440 
IAGLEHLREL QPKLDELQKL ISKKEEDVSY LSGQLSEKEA ALTKIQTEII EQEDLIKALH 

      1450       1460       1470       1480       1490       1500 
TQLEMQAKEH DERIKQLQVE LCEMKQKPEE IGEESRAKQQ IQRKLQAALI SRKEALKENK 

      1510       1520       1530       1540       1550       1560 
SLQEELSLAR GTIERLTKSL ADVESQVSAQ NKEKDTVLGR LALLQEERDK LITEMDRSLL 

      1570       1580       1590       1600       1610       1620 
ENQSLSSSCE SLKLALEGLT EDKEKLVKEI ESLKSSKIAE STEWQEKHKE LQKEYEILLQ 

      1630       1640       1650       1660       1670       1680 
SYENVSNEAE RIQHVVEAVR QEKQELYGKL RSTEANKKET EKQLQEAEQE MEEMKEKMRK 

      1690       1700       1710       1720       1730       1740 
FAKSKQQKIL ELEEENDRLR AEVHPAGDTA KECMETLLSS NASMKEELER VKMEYETLSK 

      1750       1760       1770       1780       1790       1800 
KFQSLMSEKD SLSEEVQDLK HQIEGNVSKQ ANLEATEKHD NQTNVTEEGT QSIPGETEEQ 

      1810       1820       1830       1840       1850       1860 
DSLSMSTRPT CSESVPSAKS ANPAVSKDFS SHDEINNYLQ QIDQLKERIA GLEEEKQKNK 

      1870       1880       1890       1900       1910       1920 
EFSQTLENEK NTLLSQISTK DGELKMLQEE VTKMNLLNQQ IQEELSRVTK LKETAEEEKD 

      1930       1940       1950       1960       1970       1980 
DLEERLMNQL AELNGSIGNY CQDVTDAQIK NELLESEMKN LKKCVSELEE EKQQLVKEKT 

      1990       2000       2010       2020       2030       2040 
KVESEIRKEY LEKIQGAQKE PGNKSHAKEL QELLKEKQQE VKQLQKDCIR YQEKISALER 

      2050       2060       2070       2080       2090       2100 
TVKALEFVQT ESQKDLEITK ENLAQAVEHR KKAQAELASF KVLLDDTQSE AARVLADNLK 

      2110       2120       2130       2140       2150       2160 
LKKELQSNKE SVKSQMKQKD EDLERRLEQA EEKHLKEKKN MQEKLDALRR EKVHLEETIG 

      2170       2180       2190       2200       2210       2220 
EIQVTLNKKD KEVQQLQENL DSTVTQLAAF TKSMSSLQDD RDRVIDEAKK WERKFSDAIQ 

      2230       2240       2250       2260       2270       2280 
SKEEEIRLKE DNCSVLKDQL RQMSIHMEEL KINISRLEHD KQIWESKAQT EVQLQQKVCD 

      2290       2300       2310       2320       2330       2340 
TLQGENKELL SQLEETRHLY HSSQNELAKL ESELKSLKDQ LTDLSNSLEK CKEQKGNLEG 

      2350       2360       2370       2380       2390       2400 
IIRQQEADIQ NSKFSYEQLE TDLQASRELT SRLHEEINMK EQKIISLLSG KEEAIQVAIA 

      2410       2420       2430       2440       2450       2460 
ELRQQHDKEI KELENLLSQE EEENIVLEEE NKKAVDKTNQ LMETLKTIKK ENIQQKAQLD 

      2470       2480       2490       2500       2510       2520 
SFVKSMSSLQ NDRDRIVGDY QQLEERHLSI ILEKDQLIQE AAAENNKLKE EIRGLRSHMD 

      2530       2540       2550       2560       2570       2580 
DLNSENAKLD AELIQYREDL NQVITIKDSQ QKQLLEVQLQ QNKELENKYA KLEEKLKESE 

      2590       2600       2610       2620       2630       2640 
EANEDLRRSF NALQEEKQDL SKEIESLKVS ISQLTRQVTA LQEEGTLGLY HAQLKVKEEE 

      2650       2660       2670       2680       2690       2700 
VHRLSALFSS SQKRIAELEE ELVCVQKEAA KKVGEIEDKL KKELKHLHHD AGIMRNETET 

      2710       2720       2730       2740       2750       2760 
AEERVAELAR DLVEMEQKLL MVTKENKGLT AQIQSFGRSM SSLQNSRDHA NEELDELKRK 

      2770       2780       2790       2800       2810       2820 
YDASLKELAQ LKEQGLLNRE RDALLSETAF SMNSTEENSL SHLEKLNQQL LSKDEQLLHL 

      2830       2840       2850       2860       2870       2880 
SSQLEDSYNQ VQSFSKAMAS LQNERDHLWN ELEKFRKSEE GKQRSAAQPS TSPAEVQSLK 

      2890       2900       2910       2920       2930       2940 
KAMSSLQNDR DRLLKELKNL QQQYLQINQE ITELHPLKAQ LQEYQDKTKA FQIMQEELRQ 

      2950       2960       2970       2980       2990       3000 
ENLSWQHELH QLRMEKSSWE IHERRMKEQY LMAISDKDQQ LSHLQNLIRE LRSSSSQTQP 

      3010       3020       3030       3040       3050       3060 
LKVQYQRQAS PETSASPDGS QNLVYETELL RTQLNDSLKE IHQKELRIQQ LNSNFSQLLE 

      3070       3080       3090       3100       3110       3120 
EKNTLSIQLC DTSQSLRENQ QHYGDLLNHC AVLEKQVQEL QAGPLNIDVA PGAPQEKNGV 

      3130       3140       3150       3160       3170       3180 
HRKSDPEELR EPQQSFSEAQ QQLCNTRQEV NELRKLLEEE RDQRVAAENA LSVAEEQIRR 

      3190       3200       3210       3220       3230       3240 
LEHSEWDSSR TPIIGSCGTQ EQALLIDLTS NSCRRTRSGV GWKRVLRSLC HSRTRVPLLA 

      3250 
AIYFLMIHVL LILCFTGHL 

« Hide

Isoform 2 [UniParc].

Checksum: DAF169F5D3CB6EFF
Show »

FASTA3,269377,137

References

« Hide 'large scale' references
[1]"Molecular genetic analyses of a 376-kilodalton Golgi complex membrane protein (giantin)."
Seelig H.P., Schranz P., Schroeter H., Wiemann C., Griffiths G., Renz M.
Mol. Cell. Biol. 14:2564-2576(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT ASP-1765.
[2]"Macrogolgin -- a new 376 kD Golgi complex outer membrane protein as target of antibodies in patients with rheumatic diseases and HIV infections."
Seelig H.P., Schranz P., Schroeter H., Wiemann C., Griffiths G., Renz M.
J. Autoimmun. 7:67-91(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT ASP-1765.
[3]"Molecular cloning and sequence analysis of a human 372-kDa protein localized in the Golgi complex."
Sohda M., Misumi Y., Fujiwara T., Nishioka M., Ikehara Y.
Biochem. Biophys. Res. Commun. 205:1399-1408(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[4]"Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method."
Oshikawa M., Sugai Y., Usami R., Ohtoko K., Toyama S., Kato S.
DNA Res. 15:123-136(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANTS SER-911; CYS-1212 AND ASP-1765.
Tissue: Retinal pigment epithelium.
[5]"The DNA sequence, annotation and analysis of human chromosome 3."
Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. expand/collapse author list , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]"Polo-like kinase 3 is Golgi localized and involved in regulating Golgi fragmentation during the cell cycle."
Ruan Q., Wang Q., Xie S., Fang Y., Darzynkiewicz Z., Guan K., Jhanwar-Uniyal M., Dai W.
Exp. Cell Res. 294:51-59(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH PLK3.
[8]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-17, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[9]"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[10]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-6 AND SER-17, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Leukemic T-cell.
[11]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-17 AND SER-138, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[12]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[13]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[14]"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E.
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: VARIANTS [LARGE SCALE ANALYSIS] HIS-348 AND GLY-944.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X75304 mRNA. Translation: CAA53052.1.
D25542 mRNA. Translation: BAA05025.1.
AB371588 mRNA. Translation: BAG48317.1.
AC119736 Genomic DNA. No translation available.
AC133750 Genomic DNA. No translation available.
CH471052 Genomic DNA. Translation: EAW79502.1.
CH471052 Genomic DNA. Translation: EAW79504.1.
CCDSCCDS3004.1. [Q14789-1]
CCDS58847.1. [Q14789-2]
PIRA56539.
I52300.
RefSeqNP_001243415.1. NM_001256486.1. [Q14789-2]
NP_001243416.1. NM_001256487.1.
NP_001243417.1. NM_001256488.1.
NP_004478.3. NM_004487.4. [Q14789-1]
XP_005247428.1. XM_005247371.2. [Q14789-2]
UniGeneHs.213389.
Hs.741209.

3D structure databases

ProteinModelPortalQ14789.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid109066. 15 interactions.
DIPDIP-34649N.
IntActQ14789. 19 interactions.
MINTMINT-1182261.
STRING9606.ENSP00000341848.

PTM databases

PhosphoSiteQ14789.

Polymorphism databases

DMDM145559478.

Proteomic databases

MaxQBQ14789.
PaxDbQ14789.
PRIDEQ14789.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000340645; ENSP00000341848; ENSG00000173230. [Q14789-1]
ENST00000393667; ENSP00000377275; ENSG00000173230. [Q14789-2]
GeneID2804.
KEGGhsa:2804.
UCSCuc003eei.5. human. [Q14789-1]

Organism-specific databases

CTD2804.
GeneCardsGC03M121382.
H-InvDBHIX0017595.
HGNCHGNC:4429. GOLGB1.
HPAHPA011008.
HPA011555.
MIM602500. gene.
neXtProtNX_Q14789.
PharmGKBPA28810.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG12793.
HOGENOMHOG000112754.
HOVERGENHBG051756.
InParanoidQ14789.
OMAQNLMREL.
OrthoDBEOG7RFTGC.
PhylomeDBQ14789.
TreeFamTF325082.

Gene expression databases

ArrayExpressQ14789.
BgeeQ14789.
CleanExHS_GOLGB1.
GenevestigatorQ14789.

Family and domain databases

InterProIPR026202. GOLGB1.
[Graphical view]
PANTHERPTHR18887. PTHR18887. 1 hit.
ProtoNetSearch...

Other

ChiTaRSGOLGB1. human.
GeneWikiGOLGB1.
GenomeRNAi2804.
NextBio11053.
PROQ14789.
SOURCESearch...

Entry information

Entry nameGOGB1_HUMAN
AccessionPrimary (citable) accession number: Q14789
Secondary accession number(s): B2ZZ91 expand/collapse secondary AC list , D3DN92, E7EP74, Q14398
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2003
Last sequence update: April 17, 2007
Last modified: July 9, 2014
This is version 123 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 3

Human chromosome 3: entries, gene names and cross-references to MIM