Q14769 (Q14769_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alpha-N-acetylglucosaminidase EMBL AAB36605.1

Submitted name:
N-acetylglucosaminidase, alpha-(Sanfilippo disease IIIB), isoform CRA_a EMBL EAW60832.1

Gene names

Name:	ufHSD2 EMBL AAB36605.1
Synonyms:	NAGLU EMBL EAW60832.1
ORF Names:	hCG_16571 EMBL EAW60832.1

Organism

Homo sapiens (Human) EMBL AAB36605.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	639 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Sequences

	Sequence		Length	Mass (Da)
	Q14769 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 21B47A14A2E978E6	FASTA	639	72,028
	10 20 30 40 50 60 MGDLFQGRGP SRVGCAPAHD TARRYRYYQN VCTQSYSFVW WDWARWEREI DWMALNGINL 70 80 90 100 110 120 ALAWSGQEAI WQRVYLALGL TQAEINEFFT GPAFLAWGRM GNLHTWDGPL PPSWHIKQLY 130 140 150 160 170 180 LQHRVLDQMR SFGMTPVLPA FAGHVPEAVT RVFPQVNVTK MGSWGHFNCS YSCSFLLAPE 190 200 210 220 230 240 DPIFPIIGSL FLRELIKEFG TDHIYGADTF NEMQPPSSEP SYLAAATTAV YEAMTAVDTE 250 260 270 280 290 300 AVWLLQGWLF QHQPQFWGPA QIRAVLGAVP RGRLLVLDLF AESQPVYTRT ASFQGQPFIW 310 320 330 340 350 360 CMLHNFGGNH GLFGALEAVN GGPEAARLFP NSTMVGTGMA PEGISQNEVV YSLMAELGWR 370 380 390 400 410 420 KDPVPDLAAW VTSFAARRYG VSHPDAGAAW RLLLRSVYNC SGEACRGHNR SPLVRRPSLQ 430 440 450 460 470 480 MNTSIWYNRS DVFEAWRLLL TSAPSLATSP AFRYDLLDLT RQAVQELVSL YYEEARSAYL 490 500 510 520 530 540 SKELASLLRA GGVLAYELLP ALDEVLASDS RFLLGSWLEQ ARAAAVSEAE ADFYEQNSRY 550 560 570 580 590 600 QLTLWGPEGN ILDYANKQLA GLVANYYTPR WRLFLEALVD SVAQGIPFQQ HQFDKNVFQL 610 620 630 EQAFVLSKQR YPSQPRGDTV DLAKKIFLKY YPGWVAGSW

References

[1]	"Molecular dissection of a cosmid from a gene-rich region in 17q21 and characterization of a candidate gene for alpha-N-acetylglucosaminidase with two cDNA isoforms." Zhao Z., Yazdani A., Shen Y., Sun Z.S., Bailey J., Caskey C.T., Lee C.C. Mamm. Genome 7:686-690(1996) [PubMed: 8703123] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L78465 Genomic DNA. Translation: AAB36605.1. CH471152 Genomic DNA. Translation: EAW60832.1.
IPI	IPI00008787.
UniGene	Hs.50727.
3D structure databases
ProteinModelPortal	Q14769.
ModBase	Search...
Protein-protein interaction databases
STRING	Q14769.
Protein family/group databases
CAZy	GH89. Glycoside Hydrolase Family 89.
Proteomic databases
PRIDE	Q14769.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
GeneTree	ENSGT00390000005900.
HOVERGEN	HBG004225.
Gene expression databases
ArrayExpress	Q14769.
Family and domain databases
InterPro	IPR007781. NAGLU. IPR024732. NAGLU_C. IPR024733. NAGLU_tim-barrel. [Graphical view]
PANTHER	PTHR12872. NAGLU. 1 hit.
Pfam	PF05089. NAGLU. 1 hit. PF12972. NAGLU_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q14769_HUMAN

Accession

Primary (citable) accession number: Q14769

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.