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Q146I4

- SYR_BURXL

UniProt

Q146I4 - SYR_BURXL

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Burkholderia xenovorans (strain LB400)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBXEN266265:GJII-222-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Bxeno_A0217
ORF Names:Bxe_A4245
OrganismiBurkholderia xenovorans (strain LB400)
Taxonomic identifieri266265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000001817: Chromosome 1

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 596596Arginine--tRNA ligasePRO_1000018006Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi266265.Bxe_A4245.

Structurei

3D structure databases

ProteinModelPortaliQ146I4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi139 – 14911"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiIRNTIND.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q146I4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLPAHKHTLE TLLADTVKQV ALASQGASEA AFVSPTITLE RPKVAAHGDV
60 70 80 90 100
ACNVAMQLAK PLRANPRQLA QQIVDALLAQ PGARDLVEAA EVAGPGFINL
110 120 130 140 150
RLTAAAKQAV IAAVFAEKER FGRSQRDAGK HVLIEFVSAN PTGPLHVGHG
160 170 180 190 200
RQAALGDALS NVLASQGWDV HREFYYNDAG VQIQTLALST QARARGLAPG
210 220 230 240 250
DEGWPASAYN GEYIADIAKD YLNGATVAAS DGEPVTGARD VEDLEAIRRF
260 270 280 290 300
AVAYLRREQD MDLQAFGVKF DQYYLESSLY KEGRVEKTVA ALIAAGKTYE
310 320 330 340 350
QEGALWLRTT DDGDDKDRVM RKTDGTYTYF VPDVAYHVAK WERGFTKVIN
360 370 380 390 400
IQGSDHHGTI ARVRAGLQGL GIGIPKGYPD YILHKMVTVM RNGEEVKISK
410 420 430 440 450
RAGSYVTVRD LIEWSGGATP GSEVDVDLID EETIRRGRDA VRFFLISRKA
460 470 480 490 500
DTEFVFDIDL ALKQNDENPV HYVQYAHARI CSVIAECKAR YNMDESTLAD
510 520 530 540 550
VDVTPLTSER AMALLNKLAE FPDMLQHAAD ELAPHAVAFY LRDLAGEFHS
560 570 580 590
FYNDKAERVL VDDAAERNAR VALLAATRQV LANGLATIGV SAPVKM
Length:596
Mass (Da):65,090
Last modified:August 22, 2006 - v1
Checksum:i350CAADC2EC5445C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000270 Genomic DNA. Translation: ABE28755.1.
RefSeqiWP_011486598.1. NC_007951.1.
YP_556807.1. NC_007951.1.

Genome annotation databases

EnsemblBacteriaiABE28755; ABE28755; Bxe_A4245.
GeneIDi4004021.
KEGGibxe:Bxe_A4245.
PATRICi19325771. VBIBurXen52548_0227.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000270 Genomic DNA. Translation: ABE28755.1 .
RefSeqi WP_011486598.1. NC_007951.1.
YP_556807.1. NC_007951.1.

3D structure databases

ProteinModelPortali Q146I4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266265.Bxe_A4245.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE28755 ; ABE28755 ; Bxe_A4245 .
GeneIDi 4004021.
KEGGi bxe:Bxe_A4245.
PATRICi 19325771. VBIBurXen52548_0227.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247214.
KOi K01887.
OMAi IRNTIND.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci BXEN266265:GJII-222-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LB400.

Entry informationi

Entry nameiSYR_BURXL
AccessioniPrimary (citable) accession number: Q146I4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 22, 2006
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3