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Protein

Glutamate decarboxylase

Gene

Bxe_A3826

Organism
Paraburkholderia xenovorans (strain LB400)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:Bxe_A3826Imported
OrganismiParaburkholderia xenovorans (strain LB400)Imported
Taxonomic identifieri266265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeParaburkholderia
Proteomesi
  • UP000001817 Componenti: Chromosome 1

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei274N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi266265.Bxe_A3826.

Structurei

3D structure databases

ProteinModelPortaliQ144R7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK. Bacteria.
COG0076. LUCA.
HOGENOMiHOG000070228.
KOiK01580.
OMAiFEVEPRY.
OrthoDBiPOG091H06F5.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiView protein in InterPro
IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
PANTHERiPTHR43321. PTHR43321. 1 hit.
PfamiView protein in Pfam
PF00282. Pyridoxal_deC. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q144R7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFLKSPPPT PEDVADEYAA TISGSSLPKY RIPEASSDRR AVFDLVRDEL
60 70 80 90 100
FMDGNSRQNV ATFCTTYADD EVRHLMDLSI DKNMIDKDEY PQTAEIEMRC
110 120 130 140 150
VHMLADLWHA SKAWKTTGCS TTGSSEACML GGLALKWQWK KRREAQGKPT
160 170 180 190 200
DKPNFVCGPV QVCWAKFARY FDVEMRQVPL RGEATGLTPE DLAEYCDENT
210 220 230 240 250
IGVVATLGIT FTCVYEPVKA LAGALDALQA NVGLDIPIHV DAASGGFVAP
260 270 280 290 300
FIQPDLEWDF SVPRVKSINA SGHKYGLAPL GVGWVVWRST QDLPDELIFR
310 320 330 340 350
VDYLGGDMPT FALNFSRPAG QIIAQYYMLL RLGREGYRRI QQECADTAQA
360 370 380 390 400
LADGLAKIDQ LEMIYDGRGA LPAVCYKLKH PETAGFTLFD LSDQVRMRGW
410 420 430 440 450
QIASYELPAG REDTIVQRVL IRRGVTRDMA AMLLEDIRHA IGHLTKNPVL
460
HSSAGPTFHH N
Length:461
Mass (Da):51,284
Last modified:August 22, 2006 - v1
Checksum:iFC2F69FA67A775CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000270 Genomic DNA. Translation: ABE29172.1.
RefSeqiWP_007179022.1. NZ_CP008760.1.

Genome annotation databases

EnsemblBacteriaiABE29172; ABE29172; Bxe_A3826.
GeneIDi4002521.
KEGGibxb:DR64_1503.
bxe:Bxe_A3826.
PATRICi19326643. VBIBurXen52548_0661.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000270 Genomic DNA. Translation: ABE29172.1.
RefSeqiWP_007179022.1. NZ_CP008760.1.

3D structure databases

ProteinModelPortaliQ144R7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266265.Bxe_A3826.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE29172; ABE29172; Bxe_A3826.
GeneIDi4002521.
KEGGibxb:DR64_1503.
bxe:Bxe_A3826.
PATRICi19326643. VBIBurXen52548_0661.

Phylogenomic databases

eggNOGiENOG4105CVK. Bacteria.
COG0076. LUCA.
HOGENOMiHOG000070228.
KOiK01580.
OMAiFEVEPRY.
OrthoDBiPOG091H06F5.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiView protein in InterPro
IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
PANTHERiPTHR43321. PTHR43321. 1 hit.
PfamiView protein in Pfam
PF00282. Pyridoxal_deC. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ144R7_PARXL
AccessioniPrimary (citable) accession number: Q144R7
Entry historyiIntegrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: March 15, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.