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Q14485

- Q14485_HUMAN

UniProt

Q14485 - Q14485_HUMAN

Protein
Submitted name:

Delta-hemoglobin

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
  1. Functioni

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. iron ion binding Source: InterPro
    3. oxygen binding Source: InterPro
    4. oxygen transporter activity Source: UniProtKB-KW

    Keywords - Biological processi

    Oxygen transportUniRule annotationSAAS annotation, Transport

    Keywords - Ligandi

    HemeUniRule annotationSAAS annotation, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Delta-hemoglobinImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. hemoglobin complex Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiQ14485.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-1404101.

    Structurei

    3D structure databases

    ProteinModelPortaliQ14485.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the globin family.UniRule annotation

    Family and domain databases

    Gene3Di1.10.490.10. 1 hit.
    InterProiIPR000971. Globin.
    IPR009050. Globin-like.
    IPR012292. Globin_dom.
    IPR002337. Haemoglobin_b.
    [Graphical view]
    PfamiPF00042. Globin. 1 hit.
    [Graphical view]
    PRINTSiPR00814. BETAHAEM.
    SUPFAMiSSF46458. SSF46458. 1 hit.
    PROSITEiPS01033. GLOBIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q14485-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVHLTPEEKT AVNALWGKVN VDAVGGEALG RQLVVYPWTQ RFFESFGDLS   50
    SPDAVMGNPK V 61
    Length:61
    Mass (Da):6,661
    Last modified:November 1, 1996 - v1
    Checksum:iD5DC4F2CC2DDF822
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei61 – 611Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M25661 Genomic DNA. Translation: AAA53154.1.
    PIRiI65317.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M25661 Genomic DNA. Translation: AAA53154.1 .
    PIRi I65317.

    3D structure databases

    ProteinModelPortali Q14485.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-1404101.

    Proteomic databases

    PRIDEi Q14485.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    NextBioi 35538050.

    Family and domain databases

    Gene3Di 1.10.490.10. 1 hit.
    InterProi IPR000971. Globin.
    IPR009050. Globin-like.
    IPR012292. Globin_dom.
    IPR002337. Haemoglobin_b.
    [Graphical view ]
    Pfami PF00042. Globin. 1 hit.
    [Graphical view ]
    PRINTSi PR00814. BETAHAEM.
    SUPFAMi SSF46458. SSF46458. 1 hit.
    PROSITEi PS01033. GLOBIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The beta-delta crossover leading to the beta delta hybrid gene of hemoglobin P-Nilotic is located within 54 base-pairs of the 5' end of exon 2 or between codons 31 and 50."
      Liu J.Z., Harano T., Lanclos K.D., Huisman T.H.
      Biochim. Biophys. Acta 909:208-212(1987) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ14485_HUMAN
    AccessioniPrimary (citable) accession number: Q14485
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.