Q14485 (Q14485_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Delta-hemoglobin EMBL AAA53154.1
Organism	Homo sapiens (Human) EMBL AAA53154.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	61 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the globin family. RuleBase RU000356

Ontologies

Keywords
Biological process	Oxygen transport RuleBase RU000356 SAAS SAAS002337 Transport
Ligand	Heme RuleBase RU000356 SAAS SAAS002337 Iron Metal-binding
Gene Ontology (GO)
Cellular_component	hemoglobin complex Inferred from electronic annotation. Source: InterPro
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro oxygen binding Inferred from electronic annotation. Source: InterPro oxygen transporter activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	61	1	EMBL AAA53154.1

Sequences

	Sequence		Length	Mass (Da)
	Q14485 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: D5DC4F2CC2DDF822	FASTA	61	6,661
	10 20 30 40 50 60 MVHLTPEEKT AVNALWGKVN VDAVGGEALG RQLVVYPWTQ RFFESFGDLS SPDAVMGNPK V

References

[1]	"The beta-delta crossover leading to the beta delta hybrid gene of hemoglobin P-Nilotic is located within 54 base-pairs of the 5' end of exon 2 or between codons 31 and 50." Liu J.Z., Harano T., Lanclos K.D., Huisman T.H. Biochim. Biophys. Acta 909:208-212(1987) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M25661 Genomic DNA. Translation: AAA53154.1.
IPI	IPI00791558.
PIR	I65317.
3D structure databases
ProteinModelPortal	Q14485.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-1404101.
Proteomic databases
PRIDE	Q14485.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	Q14485.
Family and domain databases
Gene3D	1.10.490.10. 1 hit.
InterPro	IPR000971. Globin. IPR009050. Globin-like. IPR012292. Globin_dom. IPR002337. Haemoglobin_b. [Graphical view]
Pfam	PF00042. Globin. 1 hit. [Graphical view]
PRINTS	PR00814. BETAHAEM.
SUPFAM	SSF46458. Globin_like. 1 hit.
PROSITE	PS01033. GLOBIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35538050.

Entry information

Entry name

Q14485_HUMAN

Accession

Primary (citable) accession number: Q14485

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	May 29, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.