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Q14485

- Q14485_HUMAN

UniProt

Q14485 - Q14485_HUMAN

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Protein
Submitted name: Delta-hemoglobin
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. oxygen binding Source: InterPro
  4. oxygen transporter activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Oxygen transportUniRule annotationSAAS annotations, Transport

Keywords - Ligandi

HemeUniRule annotationSAAS annotations, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Delta-hemoglobinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. hemoglobin complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ14485.

Interactioni

Protein-protein interaction databases

MINTiMINT-1404101.

Structurei

3D structure databases

ProteinModelPortaliQ14485.

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.UniRule annotation

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin_dom.
IPR002337. Haemoglobin_b.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00814. BETAHAEM.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q14485-1 [UniParc]FASTAAdd to Basket

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MVHLTPEEKT AVNALWGKVN VDAVGGEALG RQLVVYPWTQ RFFESFGDLS   50
SPDAVMGNPK V 61
Length:61
Mass (Da):6,661
Last modified:November 1, 1996 - v1
Checksum:iD5DC4F2CC2DDF822
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei61 – 611Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M25661 Genomic DNA. Translation: AAA53154.1.
PIRiI65317.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M25661 Genomic DNA. Translation: AAA53154.1 .
PIRi I65317.

3D structure databases

ProteinModelPortali Q14485.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-1404101.

Proteomic databases

PRIDEi Q14485.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

NextBioi 35538050.

Family and domain databases

Gene3Di 1.10.490.10. 1 hit.
InterProi IPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin_dom.
IPR002337. Haemoglobin_b.
[Graphical view ]
Pfami PF00042. Globin. 1 hit.
[Graphical view ]
PRINTSi PR00814. BETAHAEM.
SUPFAMi SSF46458. SSF46458. 1 hit.
PROSITEi PS01033. GLOBIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The beta-delta crossover leading to the beta delta hybrid gene of hemoglobin P-Nilotic is located within 54 base-pairs of the 5' end of exon 2 or between codons 31 and 50."
    Liu J.Z., Harano T., Lanclos K.D., Huisman T.H.
    Biochim. Biophys. Acta 909:208-212(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ14485_HUMAN
AccessioniPrimary (citable) accession number: Q14485
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: January 22, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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