Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q14438

- Q14438_HUMAN

UniProt

Q14438 - Q14438_HUMAN

Protein
Submitted name:

Glycophorin A

Gene

GYPA

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. cytoskeletal anchoring at plasma membrane Source: Ensembl
    2. regulation of response to osmotic stress Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glycophorin AImported
    Gene namesi
    Name:GYPAImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. external side of plasma membrane Source: Ensembl
    2. integral component of plasma membrane Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ14438.
    BgeeiQ14438.

    Family & Domainsi

    Family and domain databases

    InterProiIPR001195. Glycophorin.
    [Graphical view]
    PANTHERiPTHR13813. PTHR13813. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q14438-1 [UniParc]FASTAAdd to Basket

    « Hide

    IVSISALSTT EVAMHTSTSS SVTKSYISSQ TNDTHKRDTY AATPRAHEVS   50
    EISVRTVYPP EEETGERVQL AHHFSEP 77
    Length:77
    Mass (Da):8,475
    Last modified:November 1, 1996 - v1
    Checksum:i4381D363778DC867
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei77 – 771Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M60707 Genomic DNA. Translation: AAC34718.1.
    AY297542 Genomic DNA. Translation: AAR05990.1.
    AY297543 Genomic DNA. Translation: AAR05991.1.
    AY297545 Genomic DNA. Translation: AAR05993.1.
    AY297546 Genomic DNA. Translation: AAR05994.1.
    HQ401726 Genomic DNA. Translation: AEP34041.1.
    HQ401728 Genomic DNA. Translation: AEP34043.1.
    HQ401732 Genomic DNA. Translation: AEP34047.1.
    HQ401740 Genomic DNA. Translation: AEP34055.1.
    HQ401742 Genomic DNA. Translation: AEP34057.1.
    HQ401747 Genomic DNA. Translation: AEP34062.1.
    HQ401749 Genomic DNA. Translation: AEP34064.1.
    HQ401753 Genomic DNA. Translation: AEP34068.1.
    HQ401756 Genomic DNA. Translation: AEP34071.1.
    HQ401759 Genomic DNA. Translation: AEP34074.1.
    HQ401762 Genomic DNA. Translation: AEP34077.1.
    HQ401763 Genomic DNA. Translation: AEP34078.1.
    HQ401772 Genomic DNA. Translation: AEP34087.1.
    HQ401774 Genomic DNA. Translation: AEP34089.1.
    HQ401785 Genomic DNA. Translation: AEP34100.1.
    HQ401786 Genomic DNA. Translation: AEP34101.1.
    HQ401789 Genomic DNA. Translation: AEP34104.1.
    HQ401794 Genomic DNA. Translation: AEP34109.1.
    HQ401798 Genomic DNA. Translation: AEP34113.1.
    HQ401799 Genomic DNA. Translation: AEP34114.1.
    HQ401800 Genomic DNA. Translation: AEP34115.1.
    HQ401807 Genomic DNA. Translation: AEP34122.1.
    HQ401811 Genomic DNA. Translation: AEP34126.1.
    HQ401813 Genomic DNA. Translation: AEP34128.1.
    HQ401819 Genomic DNA. Translation: AEP34134.1.
    HQ401823 Genomic DNA. Translation: AEP34138.1.
    HQ401832 Genomic DNA. Translation: AEP34147.1.
    HQ401833 Genomic DNA. Translation: AEP34148.1.
    HQ401834 Genomic DNA. Translation: AEP34149.1.
    HQ401836 Genomic DNA. Translation: AEP34151.1.
    HQ401837 Genomic DNA. Translation: AEP34152.1.
    HQ401847 Genomic DNA. Translation: AEP34162.1.
    HQ401857 Genomic DNA. Translation: AEP34172.1.
    HQ401860 Genomic DNA. Translation: AEP34175.1.
    HQ401863 Genomic DNA. Translation: AEP34178.1.
    HQ401867 Genomic DNA. Translation: AEP34182.1.
    HQ401871 Genomic DNA. Translation: AEP34186.1.
    HQ401878 Genomic DNA. Translation: AEP34193.1.
    HQ401882 Genomic DNA. Translation: AEP34197.1.
    HQ401890 Genomic DNA. Translation: AEP34205.1.
    HQ401893 Genomic DNA. Translation: AEP34208.1.
    HQ401901 Genomic DNA. Translation: AEP34216.1.
    HQ401907 Genomic DNA. Translation: AEP34222.1.
    HQ401911 Genomic DNA. Translation: AEP34226.1.
    HQ401918 Genomic DNA. Translation: AEP34233.1.
    HQ401922 Genomic DNA. Translation: AEP34237.1.
    HQ401925 Genomic DNA. Translation: AEP34240.1.
    HQ401929 Genomic DNA. Translation: AEP34244.1.
    HQ401930 Genomic DNA. Translation: AEP34245.1.
    HQ401931 Genomic DNA. Translation: AEP34246.1.
    HQ401932 Genomic DNA. Translation: AEP34247.1.
    HQ401935 Genomic DNA. Translation: AEP34250.1.
    HQ401939 Genomic DNA. Translation: AEP34254.1.
    HQ401945 Genomic DNA. Translation: AEP34260.1.
    HQ401953 Genomic DNA. Translation: AEP34268.1.
    HQ401958 Genomic DNA. Translation: AEP34273.1.
    HQ401960 Genomic DNA. Translation: AEP34275.1.
    AJ309828 Genomic DNA. Translation: CAC82326.1.
    AJ309832 Genomic DNA. Translation: CAC82330.1.
    AJ309834 Genomic DNA. Translation: CAC82332.1.
    AJ309835 Genomic DNA. Translation: CAC83934.1.
    AJ309837 Genomic DNA. Translation: CAC83936.1.
    AJ309838 Genomic DNA. Translation: CAC83937.1.
    AJ309843 Genomic DNA. Translation: CAC83942.1.
    AJ309844 Genomic DNA. Translation: CAC83943.1.
    AJ309845 Genomic DNA. Translation: CAC83944.1.
    AJ311320 Genomic DNA. Translation: CAC85268.1.
    AJ311321 Genomic DNA. Translation: CAC85269.1.
    AJ311322 Genomic DNA. Translation: CAC85270.1.
    AJ311327 Genomic DNA. Translation: CAC85275.1.
    AJ311329 Genomic DNA. Translation: CAC85277.1.
    AJ311330 Genomic DNA. Translation: CAC85278.1.
    AJ311332 Genomic DNA. Translation: CAC85280.1.
    AJ311318 Genomic DNA. Translation: CAC85281.1.
    AJ311319 Genomic DNA. Translation: CAC85282.1.
    UniGeneiHs.434973.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M60707 Genomic DNA. Translation: AAC34718.1 .
    AY297542 Genomic DNA. Translation: AAR05990.1 .
    AY297543 Genomic DNA. Translation: AAR05991.1 .
    AY297545 Genomic DNA. Translation: AAR05993.1 .
    AY297546 Genomic DNA. Translation: AAR05994.1 .
    HQ401726 Genomic DNA. Translation: AEP34041.1 .
    HQ401728 Genomic DNA. Translation: AEP34043.1 .
    HQ401732 Genomic DNA. Translation: AEP34047.1 .
    HQ401740 Genomic DNA. Translation: AEP34055.1 .
    HQ401742 Genomic DNA. Translation: AEP34057.1 .
    HQ401747 Genomic DNA. Translation: AEP34062.1 .
    HQ401749 Genomic DNA. Translation: AEP34064.1 .
    HQ401753 Genomic DNA. Translation: AEP34068.1 .
    HQ401756 Genomic DNA. Translation: AEP34071.1 .
    HQ401759 Genomic DNA. Translation: AEP34074.1 .
    HQ401762 Genomic DNA. Translation: AEP34077.1 .
    HQ401763 Genomic DNA. Translation: AEP34078.1 .
    HQ401772 Genomic DNA. Translation: AEP34087.1 .
    HQ401774 Genomic DNA. Translation: AEP34089.1 .
    HQ401785 Genomic DNA. Translation: AEP34100.1 .
    HQ401786 Genomic DNA. Translation: AEP34101.1 .
    HQ401789 Genomic DNA. Translation: AEP34104.1 .
    HQ401794 Genomic DNA. Translation: AEP34109.1 .
    HQ401798 Genomic DNA. Translation: AEP34113.1 .
    HQ401799 Genomic DNA. Translation: AEP34114.1 .
    HQ401800 Genomic DNA. Translation: AEP34115.1 .
    HQ401807 Genomic DNA. Translation: AEP34122.1 .
    HQ401811 Genomic DNA. Translation: AEP34126.1 .
    HQ401813 Genomic DNA. Translation: AEP34128.1 .
    HQ401819 Genomic DNA. Translation: AEP34134.1 .
    HQ401823 Genomic DNA. Translation: AEP34138.1 .
    HQ401832 Genomic DNA. Translation: AEP34147.1 .
    HQ401833 Genomic DNA. Translation: AEP34148.1 .
    HQ401834 Genomic DNA. Translation: AEP34149.1 .
    HQ401836 Genomic DNA. Translation: AEP34151.1 .
    HQ401837 Genomic DNA. Translation: AEP34152.1 .
    HQ401847 Genomic DNA. Translation: AEP34162.1 .
    HQ401857 Genomic DNA. Translation: AEP34172.1 .
    HQ401860 Genomic DNA. Translation: AEP34175.1 .
    HQ401863 Genomic DNA. Translation: AEP34178.1 .
    HQ401867 Genomic DNA. Translation: AEP34182.1 .
    HQ401871 Genomic DNA. Translation: AEP34186.1 .
    HQ401878 Genomic DNA. Translation: AEP34193.1 .
    HQ401882 Genomic DNA. Translation: AEP34197.1 .
    HQ401890 Genomic DNA. Translation: AEP34205.1 .
    HQ401893 Genomic DNA. Translation: AEP34208.1 .
    HQ401901 Genomic DNA. Translation: AEP34216.1 .
    HQ401907 Genomic DNA. Translation: AEP34222.1 .
    HQ401911 Genomic DNA. Translation: AEP34226.1 .
    HQ401918 Genomic DNA. Translation: AEP34233.1 .
    HQ401922 Genomic DNA. Translation: AEP34237.1 .
    HQ401925 Genomic DNA. Translation: AEP34240.1 .
    HQ401929 Genomic DNA. Translation: AEP34244.1 .
    HQ401930 Genomic DNA. Translation: AEP34245.1 .
    HQ401931 Genomic DNA. Translation: AEP34246.1 .
    HQ401932 Genomic DNA. Translation: AEP34247.1 .
    HQ401935 Genomic DNA. Translation: AEP34250.1 .
    HQ401939 Genomic DNA. Translation: AEP34254.1 .
    HQ401945 Genomic DNA. Translation: AEP34260.1 .
    HQ401953 Genomic DNA. Translation: AEP34268.1 .
    HQ401958 Genomic DNA. Translation: AEP34273.1 .
    HQ401960 Genomic DNA. Translation: AEP34275.1 .
    AJ309828 Genomic DNA. Translation: CAC82326.1 .
    AJ309832 Genomic DNA. Translation: CAC82330.1 .
    AJ309834 Genomic DNA. Translation: CAC82332.1 .
    AJ309835 Genomic DNA. Translation: CAC83934.1 .
    AJ309837 Genomic DNA. Translation: CAC83936.1 .
    AJ309838 Genomic DNA. Translation: CAC83937.1 .
    AJ309843 Genomic DNA. Translation: CAC83942.1 .
    AJ309844 Genomic DNA. Translation: CAC83943.1 .
    AJ309845 Genomic DNA. Translation: CAC83944.1 .
    AJ311320 Genomic DNA. Translation: CAC85268.1 .
    AJ311321 Genomic DNA. Translation: CAC85269.1 .
    AJ311322 Genomic DNA. Translation: CAC85270.1 .
    AJ311327 Genomic DNA. Translation: CAC85275.1 .
    AJ311329 Genomic DNA. Translation: CAC85277.1 .
    AJ311330 Genomic DNA. Translation: CAC85278.1 .
    AJ311332 Genomic DNA. Translation: CAC85280.1 .
    AJ311318 Genomic DNA. Translation: CAC85281.1 .
    AJ311319 Genomic DNA. Translation: CAC85282.1 .
    UniGenei Hs.434973.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Gene expression databases

    ArrayExpressi Q14438.
    Bgeei Q14438.

    Family and domain databases

    InterProi IPR001195. Glycophorin.
    [Graphical view ]
    PANTHERi PTHR13813. PTHR13813. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Identification of recombination events resulting in three hybrid genes encoding human MiV, MiV(J.L.), and Sta glycophorins."
      Huang C.H., Blumenfeld O.O.
      Blood 77:1813-1820(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BloodImported.
    2. "Molecular genetics of human erythrocyte MiIII and MiVI glycophorins. Use of a pseudoexon in construction of two delta-alpha-delta hybrid genes resulting in antigenic diversification."
      Huang C.-H., Blumenfeld O.O.
      J. Biol. Chem. 266:7248-7255(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BloodImported.
    3. Blumenfeld O.O.
      Submitted (APR-1993) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BloodImported.
    4. "Natural selection on the erythrocyte surface."
      Baum J., Ward R.H., Conway D.J.
      Mol. Biol. Evol. 19:223-229(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: A1Imported, C1Imported, C2Imported, D2Imported, E1Imported, F1Imported, F2Imported, G2Imported, H1Imported, N1037Imported, N1099Imported, N1117Imported, N1118Imported, N1238Imported, N1339Imported, N1369Imported, N1436Imported and N944Imported.
    5. "Rapidly evolving genes in human. I. The glycophorins and their possible role in evading malaria parasites."
      Wang H.Y., Tang H., Shen C.K., Wu C.I.
      Mol. Biol. Evol. 20:1795-1804(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    6. "Adaptive evolution of human glycophorin loci in malaria endemic African populations."
      Ko W.-Y., Kaercher K.A., Giombini E., Marcatili P., Froment A., Ibrahim M., Lema G., Nyambo T.B., Omar S.A., Wambebe C., Ranciaro A., Hirbo J.B., Tishkoff S.A.
      Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ14438_HUMAN
    AccessioniPrimary (citable) accession number: Q14438
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.