##gff-version 3
Q14320	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:22814378;Dbxref=PMID:22814378	
Q14320	UniProtKB	Chain	2	339	.	.	.	ID=PRO_0000068284;Note=Protein FAM50A	
Q14320	UniProtKB	Region	1	31	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14320	UniProtKB	Region	121	177	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14320	UniProtKB	Motif	152	155	.	.	.	Note=Nuclear localization signal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q14320	UniProtKB	Compositional bias	14	31	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14320	UniProtKB	Compositional bias	125	143	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14320	UniProtKB	Compositional bias	144	177	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14320	UniProtKB	Modified residue	2	2	.	.	.	Note=N-acetylalanine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:22814378;Dbxref=PMID:22814378	
Q14320	UniProtKB	Cross-link	100	100	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:28112733;Dbxref=PMID:28112733	
Q14320	UniProtKB	Natural variant	137	137	.	.	.	ID=VAR_084563;Note=It rescues craniofacial patterning defects in zebrafish morphant embryos. A->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32703943;Dbxref=dbSNP:rs149558328,PMID:32703943	
Q14320	UniProtKB	Natural variant	143	143	.	.	.	ID=VAR_084564;Note=It rescues craniofacial patterning defects in zebrafish morphant embryos. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32703943;Dbxref=dbSNP:rs782017549,PMID:32703943	
Q14320	UniProtKB	Natural variant	206	206	.	.	.	ID=VAR_084565;Note=In MRXSA%3B uncertain significance%3B does not affect FAM50A protein levels in patient cells%3B does not affect localization to the nucleus. W->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32703943;Dbxref=dbSNP:rs2068793121,PMID:32703943	
Q14320	UniProtKB	Natural variant	254	254	.	.	.	ID=VAR_084566;Note=In MRXSA%3B hypomorphic variant%3B does not fully rescue craniofacial patterning defects in zebrafish morphant embryos%3B does not affect FAM50A protein levels in patient cells%3B does not affect localization to the nucleus. E->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32703943;Dbxref=dbSNP:rs2068797150,PMID:32703943	
Q14320	UniProtKB	Natural variant	255	255	.	.	.	ID=VAR_084567;Note=In MRXSA%3B hypomorphic variant%3B does not fully rescue craniofacial patterning defects in zebrafish morphant embryos%3B does not affect localization to the nucleus. D->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32703943;Dbxref=dbSNP:rs2068797192,PMID:32703943	
Q14320	UniProtKB	Natural variant	255	255	.	.	.	ID=VAR_084568;Note=In MRXSA%3B hypomorphic variant%3B does not fully rescue craniofacial patterning defects in zebrafish morphant embryos. D->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32703943;Dbxref=dbSNP:rs2068797171,PMID:32703943	
Q14320	UniProtKB	Natural variant	273	273	.	.	.	ID=VAR_084569;Note=In MRXSA%3B hypomorphic variant%3B does not fully rescue craniofacial patterning defects in zebrafish morphant embryos. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32703943;Dbxref=dbSNP:rs2068798311,PMID:32703943	
Q14320	UniProtKB	Sequence conflict	166	166	.	.	.	Note=F->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q14320	UniProtKB	Sequence conflict	330	330	.	.	.	Note=E->G;Ontology_term=ECO:0000305;evidence=ECO:0000305