Q142S4 (TAL_BURXL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	Bxeno_A1127
ORF Names:	Bxe_A3318

Organism

Burkholderia xenovorans (strain LB400) [Complete proteome] [HAMAP]

Taxonomic identifier

266265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length	317 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00492
Subcellular location	Cytoplasm By similarity HAMAP MF_00492.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 317	317	Transaldolase HAMAP MF_00492		PRO_1000014496
Sites
	Active site	126	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q142S4 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: D9B159FC994939E7	FASTA	317	34,908
	10 20 30 40 50 60 MTTALDQLKQ YTTVVADTGD FQQLAQYKPQ DATTNPSLIL KAVQKDDYKP LLEKTVKAHA 70 80 90 100 110 120 SKPVGAIIDQ LLIAFGTEIL KIIPGRVSTE VDARLSFDTE GSIAKGRELI ALYKEHGIGR 130 140 150 160 170 180 ERVLIKLAST WEGIRAAEVL QKEGIHCNMT LLFSLAQAAA CAEAGAQLIS PFVGRIYDWY 190 200 210 220 230 240 KKNAGSAWDE AKDGGANDPG VKSVRRIYAY YKKFGYKTEV MGASFRTPGQ ILELAGCDLL 250 260 270 280 290 300 TISPDLLQKL HESTEKVERK LSPDIAKESD IERVPVDESS FRFLVNDEAM ATEKLAEGIR 310 AFAADAIKLE KLIDALR

References

[1]

"Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility." Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L., Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J., Parnell J.J. , Ramette A., Richardson P., Seeger M., Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M. Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006) [PubMed: 17030797] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LB400.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000270 Genomic DNA. Translation: ABE29665.1.
RefSeq	YP_557717.1. NC_007951.1.
3D structure databases
ProteinModelPortal	Q142S4.
SMR	Q142S4. Positions 1-315.
ModBase	Search...
Protein-protein interaction databases
STRING	Q142S4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4002123.
GenomeReviews	Gene locus Bxeno_A1127 in contig CP000270_GR.
KEGG	bxe:Bxe_A3318.
PATRIC	19327648. VBIBurXen52548_1160.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG286747.
OMA	GCEILAI.
PhylomeDB	Q142S4.
ProtClustDB	PRK05269.
Family and domain databases
HAMAP	MF_00492. Transaldolase_1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_1. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. TalAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_BURXL

Accession

Primary (citable) accession number: Q142S4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 22, 2006
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program