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Q142C4 (Q142C4_BURXL) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902
Gene names
Name:dnaE2 HAMAP MF_01902
Ordered Locus Names:Bxeno_A1277
ORF Names:Bxe_A3164 EMBL ABE29815.1
OrganismBurkholderia xenovorans (strain LB400) [Complete proteome] [HAMAP]
Taxonomic identifier266265 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length1195 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013

Subcellular location

Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.

Sequence similarities

Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Sequences

Sequence LengthMass (Da)Tools
Q142C4 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 5919B9A37919B585

FASTA1,195133,325
        10         20         30         40         50         60 
MPLSQSPFLA KQTLATHLPA YAELHCLTNF SFLRGASHPY ELVEQAMSRG YSALAITDEC 

        70         80         90        100        110        120 
SLAGVVRAHT ALKEIREERE RQQKEREDKA KAAKAAQAAV PLEDASKAGF IQQEAEEIED 

       130        140        150        160        170        180 
AESLKPLPHL IIGSEFNLTD ETGEPFCTLV ALATNRNGYG NLSELITLAR SRADKGSYRL 

       190        200        210        220        230        240 
GPSDFTDSLP HLAHLQTLPD CVLMLVPQRA ATLSHTLRCA HWLASFAAQR AWIALELWQT 

       250        260        270        280        290        300 
GSDDLQIDAL RMISKASGLP LVAAGGVLMH ARSRKPLQDT MTAIGLVTPL SACGHALEAN 

       310        320        330        340        350        360 
AERHMRTRVR LGKLYPRDTL EETLRIAALC RFSLDELKYE YPEELVPAGE SPSSYLRKLV 

       370        380        390        400        410        420 
MAGAMERWPE GMDLKRIGQI EKELALIADL KYEKYFLTVH DIVSFARSRN ILCQGRGSAA 

       430        440        450        460        470        480 
NSIVCYCLHV TEIDPVQMNM LIERFISRAR NEPPDIDVDF EHQRREEVIQ YIYTKYGRHR 

       490        500        510        520        530        540 
AALTASLITY HARSALKDVG KALGLEASLI ERISKSQQWW DGTDAVAGYL AEAGFDANSH 

       550        560        570        580        590        600 
ITQNLIRLTR ELRSFPRHLS QHVGGFVIAK DKLSRLVPIE NATMKDRSVI EWDKDDIDAL 

       610        620        630        640        650        660 
KLLKVDVLAL GMLSAIRRAL EFVALRRGFP QFRVQDIPRE DRAVYEMCGH ADTIGVFQIE 

       670        680        690        700        710        720 
SRAQQSMLPR LKPNKYYDLV IEVAIVRPGP IQGGMVHPYL RRKQGLEPVD YAKDELRPVL 

       730        740        750        760        770        780 
ERTLGVPIFQ EQVMHLAMVA AEYTGEQADQ LRRAMAAWRR SGNLAKYQKD LNERMLRRGY 

       790        800        810        820        830        840 
EQAFIDRICK QIEGFGEYGF PESHAASFAL LVYLSAWLKR YEPAAFLAGL LNSQPLGFYS 

       850        860        870        880        890        900 
PSQLVQDAKR HGVKILPPDV TLSDWESTFE RRGHEGRRIS SDETCLHRQQ TVLSAQQLRD 

       910        920        930        940        950        960 
LSLRRLTVSR TVRRAAQRLT ARVFQPSNTY GARGPAVRIG MHLIKGLTQG AAERIMAARH 

       970        980        990       1000       1010       1020 
DAQFTDVDDL ARRAALTRRD LEALAAANAL VSIAGHRREA WWAVTAQHAV PRLLRDAPIA 

      1030       1040       1050       1060       1070       1080 
EAALALPQAA ESREIVDDYA SLGLTLNRHP LALLRARLAR QRFRTAAELT ACQHGTLARA 

      1090       1100       1110       1120       1130       1140 
CGIVTVRQRP GTANGTVFVS IEDETGSINV IVWPSLVEKQ RKVLLGASLL AVYGVLQRDD 

      1150       1160       1170       1180       1190 
GVATGGNHSG NGVHANQAGK AKQKHKGEVI HLVAHRLEDH SEWLGDLATA SRDFH

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000270 Genomic DNA. Translation: ABE29815.1.
RefSeqYP_557867.1. NC_007951.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ142C4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4002734.
GenomeReviewsGene locus Bxeno_A1277 in contig CP000270_GR.
KEGGbxe:Bxe_A3164.
PATRIC19327974. VBIBurXen52548_1317.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG734490.
OMALATNRNG.
ProtClustDBCLSK2314123.

Family and domain databases

HAMAPMF_01902. DNApol_error_prone.
[Tree]
InterProIPR011708. DNA_pol3_alpha.
IPR023073. DNA_pol_error_prone.
IPR004365. NA-bd_OB_tRNA-helicase.
IPR004013. PHP_C.
IPR003141. Pol/His_phosphatase_N.
IPR016195. Pol/histidinol_Pase-like.
IPR004805. PolC_alpha.
[Graphical view]
KOK14162.
PfamPF07733. DNA_pol3_alpha. 1 hit.
PF02811. PHP. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
SMARTSM00481. POLIIIAc. 1 hit.
[Graphical view]
SUPFAMSSF89550. PHP-like. 1 hit.
TIGRFAMsTIGR00594. Polc. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ142C4_BURXL
AccessionPrimary (citable) accession number: Q142C4
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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