##gff-version 3
Q14185	UniProtKB	Chain	1	1865	.	.	.	ID=PRO_0000189984;Note=Dedicator of cytokinesis protein 1	
Q14185	UniProtKB	Domain	9	70	.	.	.	Note=SH3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00192	
Q14185	UniProtKB	Domain	425	609	.	.	.	Note=C2 DOCK-type;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00983	
Q14185	UniProtKB	Domain	1207	1617	.	.	.	Note=DOCKER;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00984	
Q14185	UniProtKB	Region	1619	1716	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14185	UniProtKB	Region	1687	1695	.	.	.	Note=Phosphoinositide-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q14185	UniProtKB	Region	1732	1865	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14185	UniProtKB	Region	1793	1819	.	.	.	Note=Interaction with NCK2 second and third SH3 domain (minor)	
Q14185	UniProtKB	Region	1820	1836	.	.	.	Note=Interaction with NCK2 third SH3 domain (major)	
Q14185	UniProtKB	Region	1837	1852	.	.	.	Note=Interaction with NCK2 (minor)	
Q14185	UniProtKB	Motif	1799	1805	.	.	.	Note=SH3-binding%3B interaction with CRK;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q14185	UniProtKB	Motif	1838	1843	.	.	.	Note=SH3-binding%3B interaction with CRK;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q14185	UniProtKB	Compositional bias	1633	1662	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14185	UniProtKB	Compositional bias	1676	1715	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14185	UniProtKB	Compositional bias	1732	1762	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14185	UniProtKB	Compositional bias	1770	1789	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14185	UniProtKB	Compositional bias	1822	1853	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q14185	UniProtKB	Modified residue	1681	1681	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:23186163,ECO:0007744|PubMed:24275569;Dbxref=PMID:23186163,PMID:24275569	
Q14185	UniProtKB	Modified residue	1743	1743	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8BUR4	
Q14185	UniProtKB	Modified residue	1751	1751	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:18669648;Dbxref=PMID:18669648	
Q14185	UniProtKB	Modified residue	1756	1756	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8BUR4	
Q14185	UniProtKB	Modified residue	1761	1761	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8BUR4	
Q14185	UniProtKB	Modified residue	1764	1764	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8BUR4	
Q14185	UniProtKB	Modified residue	1767	1767	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8BUR4	
Q14185	UniProtKB	Modified residue	1772	1772	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8BUR4	
Q14185	UniProtKB	Modified residue	1858	1858	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8BUR4	
Q14185	UniProtKB	Natural variant	1793	1793	.	.	.	ID=VAR_059971;Note=A->T;Dbxref=dbSNP:rs869801	
Q14185	UniProtKB	Mutagenesis	1401	1402	.	.	.	Note=Abolishes Rac GEF activity. YI->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12134158;Dbxref=PMID:12134158	
Q14185	UniProtKB	Mutagenesis	1487	1489	.	.	.	Note=Abolishes Rac GEF activity. ISP->AAA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12134158;Dbxref=PMID:12134158	
Q14185	UniProtKB	Sequence conflict	1857	1857	.	.	.	Note=A->T;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q14185	UniProtKB	Beta strand	426	436	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Beta strand	440	444	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Beta strand	448	456	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Beta strand	493	499	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Beta strand	507	515	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Beta strand	528	537	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Beta strand	546	555	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Helix	558	561	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Helix	564	567	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Helix	574	578	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C	
Q14185	UniProtKB	Beta strand	595	608	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3L4C