Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q14162

- SREC_HUMAN

UniProt

Q14162 - SREC_HUMAN

Protein

Scavenger receptor class F member 1

Gene

SCARF1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 134 (01 Oct 2014)
      Sequence version 3 (02 Nov 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth By similarity.By similarity

    GO - Molecular functioni

    1. low-density lipoprotein particle binding Source: UniProtKB
    2. scavenger receptor activity Source: UniProtKB
    3. transmembrane signaling receptor activity Source: UniProtKB

    GO - Biological processi

    1. cell adhesion Source: UniProtKB-KW
    2. cholesterol catabolic process Source: UniProtKB
    3. dendrite development Source: Ensembl
    4. neuron remodeling Source: UniProtKB
    5. positive regulation of axon regeneration Source: UniProtKB
    6. positive regulation of neuron projection development Source: UniProtKB
    7. receptor-mediated endocytosis Source: UniProtKB
    8. signal transduction Source: GOC

    Keywords - Molecular functioni

    Receptor

    Keywords - Biological processi

    Cell adhesion

    Enzyme and pathway databases

    ReactomeiREACT_163813. Scavenging by Class F Receptors.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Scavenger receptor class F member 1
    Alternative name(s):
    Acetyl LDL receptor
    Scavenger receptor expressed by endothelial cells 1
    Short name:
    SREC-I
    Gene namesi
    Name:SCARF1
    Synonyms:KIAA0149, SREC
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:16820. SCARF1.

    Subcellular locationi

    GO - Cellular componenti

    1. endocytic vesicle membrane Source: Reactome
    2. integral component of membrane Source: UniProtKB
    3. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA38420.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 830811Scavenger receptor class F member 1PRO_0000007738Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi57 ↔ 69PROSITE-ProRule annotation
    Disulfide bondi63 ↔ 75PROSITE-ProRule annotation
    Disulfide bondi77 ↔ 86PROSITE-ProRule annotation
    Disulfide bondi99 ↔ 111PROSITE-ProRule annotation
    Disulfide bondi105 ↔ 118PROSITE-ProRule annotation
    Disulfide bondi120 ↔ 129PROSITE-ProRule annotation
    Disulfide bondi159 ↔ 172PROSITE-ProRule annotation
    Disulfide bondi165 ↔ 179PROSITE-ProRule annotation
    Disulfide bondi181 ↔ 190PROSITE-ProRule annotation
    Disulfide bondi219 ↔ 230PROSITE-ProRule annotation
    Disulfide bondi225 ↔ 237PROSITE-ProRule annotation
    Disulfide bondi239 ↔ 248PROSITE-ProRule annotation
    Glycosylationi289 – 2891N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi306 ↔ 319PROSITE-ProRule annotation
    Disulfide bondi313 ↔ 326PROSITE-ProRule annotation
    Disulfide bondi329 ↔ 338PROSITE-ProRule annotation
    Disulfide bondi355 ↔ 363PROSITE-ProRule annotation
    Disulfide bondi358 ↔ 370PROSITE-ProRule annotation
    Disulfide bondi372 ↔ 381PROSITE-ProRule annotation
    Glycosylationi382 – 3821N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi393 – 3931N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiQ14162.
    PRIDEiQ14162.

    PTM databases

    PhosphoSiteiQ14162.

    Expressioni

    Tissue specificityi

    Endothelial cells.

    Gene expression databases

    ArrayExpressiQ14162.
    BgeeiQ14162.
    CleanExiHS_SCARF1.
    GenevestigatoriQ14162.

    Organism-specific databases

    HPAiHPA035108.

    Interactioni

    Subunit structurei

    Heterophilic interaction with SREC2 via its extracellular domain. The heterophilic interaction is suppressed by the presence of ligand such as Ac-LDL. Interacts with AVIL By similarity.By similarity

    Protein-protein interaction databases

    STRINGi9606.ENSP00000263071.

    Structurei

    3D structure databases

    ProteinModelPortaliQ14162.
    SMRiQ14162. Positions 37-415.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini20 – 421402ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini443 – 830388CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei422 – 44221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini53 – 8735EGF-like 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini95 – 13036EGF-like 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini155 – 19137EGF-like 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini215 – 24935EGF-like 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini302 – 33938EGF-like 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini351 – 38232EGF-like 6PROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi431 – 4388Poly-Leu
    Compositional biasi476 – 620145Pro/Ser-richAdd
    BLAST
    Compositional biasi622 – 798177Gly-richAdd
    BLAST

    Sequence similaritiesi

    Contains 6 EGF-like domains.PROSITE-ProRule annotation

    Keywords - Domaini

    EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG284054.
    HOGENOMiHOG000015093.
    HOVERGENiHBG099941.
    InParanoidiQ14162.
    OMAiPAYCVPP.
    OrthoDBiEOG77HDD8.
    PhylomeDBiQ14162.
    TreeFamiTF332598.

    Family and domain databases

    InterProiIPR000742. EG-like_dom.
    IPR013032. EGF-like_CS.
    IPR002049. EGF_laminin.
    IPR009030. Growth_fac_rcpt_N_dom.
    [Graphical view]
    PfamiPF12661. hEGF. 3 hits.
    PF00053. Laminin_EGF. 1 hit.
    [Graphical view]
    SMARTiSM00181. EGF. 5 hits.
    [Graphical view]
    SUPFAMiSSF57184. SSF57184. 1 hit.
    PROSITEiPS00022. EGF_1. 6 hits.
    PS01186. EGF_2. 6 hits.
    PS50026. EGF_3. 3 hits.
    [Graphical view]

    Sequences (5)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 5 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q14162-1) [UniParc]FASTAAdd to Basket

    Also known as: SREC-1

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MGLGLLLPLL LLWTRGTQGS ELDPKGQHVC VASSPSAELQ CCAGWRQKDQ    50
    ECTIPICEGP DACQKDEVCV KPGLCRCKPG FFGAHCSSRC PGQYWGPDCR 100
    ESCPCHPHGQ CEPATGACQC QADRWGARCE FPCACGPHGR CDPATGVCHC 150
    EPGWWSSTCR RPCQCNTAAA RCEQATGACV CKPGWWGRRC SFRCNCHGSP 200
    CEQDSGRCAC RPGWWGPECQ QQCECVRGRC SAASGECTCP PGFRGARCEL 250
    PCPAGSHGVQ CAHSCGRCKH NEPCSPDTGS CESCEPGWNG TQCQQPCLPG 300
    TFGESCEQQC PHCRHGEACE PDTGHCQRCD PGWLGPRCED PCPTGTFGED 350
    CGSTCPTCVQ GSCDTVTGDC VCSAGYWGPS CNASCPAGFH GNNCSVPCEC 400
    PEGLCHPVSG SCQPGSGSRD TALIAGSLVP LLLLFLGLAC CACCCWAPRS 450
    DLKDRPARDG ATVSRMKLQV WGTLTSLGST LPCRSLSSHK LPWVTVSHHD 500
    PEVPFNHSFI EPPSAGWATD DSFSSDPESG EADEVPAYCV PPQEGMVPVA 550
    QAGSSEASLA AGAFPPPEDA STPFAIPRTS SLARAKRPSV SFAEGTKFAP 600
    QSRRSSGELS SPLRKPKRLS RGAQSGPEGR EAEESTGPEE AEAPESFPAA 650
    ASPGDSATGH RRPPLGGRTV AEHVEAIEGS VQESSGPVTT IYMLAGKPRG 700
    SEGPVRSVFR HFGSFQKGQA EAKVKRAIPK PPRQALNRKK GSPGLASGSV 750
    GQSPNSAPKA GLPGATGPMA VRPEEAVRGL GAGTESSRRA QEPVSGCGSP 800
    EQDPQKQAEE ERQEEPEYEN VVPISRPPEP 830
    Length:830
    Mass (Da):87,387
    Last modified:November 2, 2010 - v3
    Checksum:i3D1CBF0D6F2BA055
    GO
    Isoform 2 (identifier: Q14162-2) [UniParc]FASTAAdd to Basket

    Also known as: SREC-5

    The sequence of this isoform differs from the canonical sequence as follows:
         330-415: Missing.

    Show »
    Length:744
    Mass (Da):78,783
    Checksum:iA924B3B4B76D6948
    GO
    Isoform 3 (identifier: Q14162-3) [UniParc]FASTAAdd to Basket

    Also known as: SREC-3

    The sequence of this isoform differs from the canonical sequence as follows:
         496-569: VSHHDPEVPF...AAGAFPPPED → ASSSRPLPAG...RHSPSRAPPA
         570-830: Missing.

    Show »
    Length:569
    Mass (Da):60,820
    Checksum:i3ACECF49DBC21675
    GO
    Isoform 4 (identifier: Q14162-4) [UniParc]FASTAAdd to Basket

    Also known as: SREC-4

    The sequence of this isoform differs from the canonical sequence as follows:
         338-830: Missing.

    Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

    Show »
    Length:337
    Mass (Da):36,240
    Checksum:iB5F0FAE77445A44D
    GO
    Isoform 5 (identifier: Q14162-5) [UniParc]FASTAAdd to Basket

    Also known as: SREC-2

    The sequence of this isoform differs from the canonical sequence as follows:
         338-342: CEDPC → GPVIL
         343-830: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:342
    Mass (Da):36,720
    Checksum:iE177E94FCE55F0FA
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti328 – 3292RC → PG in BAC02696. (PubMed:11978792)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti425 – 4251A → V.5 Publications
    Corresponds to variant rs2272011 [ dbSNP | Ensembl ].
    VAR_047249
    Natural varianti618 – 6181R → K.
    Corresponds to variant rs35455643 [ dbSNP | Ensembl ].
    VAR_047250
    Natural varianti639 – 6391E → D.4 Publications
    Corresponds to variant rs3744644 [ dbSNP | Ensembl ].
    VAR_047251
    Natural varianti662 – 6621R → W.2 Publications
    Corresponds to variant rs8072430 [ dbSNP | Ensembl ].
    VAR_047252
    Natural varianti667 – 6671G → S.4 Publications
    Corresponds to variant rs4790250 [ dbSNP | Ensembl ].
    VAR_047253
    Natural varianti748 – 7481G → V.
    Corresponds to variant rs3760460 [ dbSNP | Ensembl ].
    VAR_047254

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei330 – 41586Missing in isoform 2. 1 PublicationVSP_039956Add
    BLAST
    Alternative sequencei338 – 830493Missing in isoform 4. 1 PublicationVSP_039957Add
    BLAST
    Alternative sequencei338 – 3425CEDPC → GPVIL in isoform 5. 1 PublicationVSP_039958
    Alternative sequencei343 – 830488Missing in isoform 5. 1 PublicationVSP_039959Add
    BLAST
    Alternative sequencei496 – 56974VSHHD…PPPED → ASSSRPLPAGPLMTPSHPIL SLERQMRFLPTVCHPKKGWS LWPRQGRQRPAWLQVLSRPL RTPPRHSPSRAPPA in isoform 3. 1 PublicationVSP_039960Add
    BLAST
    Alternative sequencei570 – 830261Missing in isoform 3. 1 PublicationVSP_039961Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D86864 mRNA. Translation: BAA24070.1.
    AB052946 Genomic DNA. Translation: BAC02692.1.
    AB052947 mRNA. Translation: BAC02693.1.
    AB052948 mRNA. Translation: BAC02694.1.
    AB052949 mRNA. Translation: BAC02695.1.
    AB052950 mRNA. Translation: BAC02696.1.
    D63483 mRNA. Translation: BAA09770.1.
    AC130343 Genomic DNA. No translation available.
    CH471108 Genomic DNA. Translation: EAW90596.1.
    BC039735 mRNA. Translation: AAH39735.1.
    CCDSiCCDS11007.1. [Q14162-1]
    CCDS45564.1. [Q14162-3]
    RefSeqiNP_003684.2. NM_003693.3. [Q14162-1]
    NP_663325.1. NM_145350.2. [Q14162-3]
    UniGeneiHs.647430.

    Genome annotation databases

    EnsembliENST00000263071; ENSP00000263071; ENSG00000074660. [Q14162-1]
    ENST00000348987; ENSP00000323964; ENSG00000074660. [Q14162-2]
    ENST00000434376; ENSP00000411167; ENSG00000074660. [Q14162-5]
    ENST00000571272; ENSP00000458174; ENSG00000074660. [Q14162-3]
    GeneIDi8578.
    KEGGihsa:8578.
    UCSCiuc002fsy.2. human. [Q14162-3]
    uc002fsz.2. human. [Q14162-1]

    Polymorphism databases

    DMDMi311033530.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D86864 mRNA. Translation: BAA24070.1 .
    AB052946 Genomic DNA. Translation: BAC02692.1 .
    AB052947 mRNA. Translation: BAC02693.1 .
    AB052948 mRNA. Translation: BAC02694.1 .
    AB052949 mRNA. Translation: BAC02695.1 .
    AB052950 mRNA. Translation: BAC02696.1 .
    D63483 mRNA. Translation: BAA09770.1 .
    AC130343 Genomic DNA. No translation available.
    CH471108 Genomic DNA. Translation: EAW90596.1 .
    BC039735 mRNA. Translation: AAH39735.1 .
    CCDSi CCDS11007.1. [Q14162-1 ]
    CCDS45564.1. [Q14162-3 ]
    RefSeqi NP_003684.2. NM_003693.3. [Q14162-1 ]
    NP_663325.1. NM_145350.2. [Q14162-3 ]
    UniGenei Hs.647430.

    3D structure databases

    ProteinModelPortali Q14162.
    SMRi Q14162. Positions 37-415.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000263071.

    PTM databases

    PhosphoSitei Q14162.

    Polymorphism databases

    DMDMi 311033530.

    Proteomic databases

    PaxDbi Q14162.
    PRIDEi Q14162.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000263071 ; ENSP00000263071 ; ENSG00000074660 . [Q14162-1 ]
    ENST00000348987 ; ENSP00000323964 ; ENSG00000074660 . [Q14162-2 ]
    ENST00000434376 ; ENSP00000411167 ; ENSG00000074660 . [Q14162-5 ]
    ENST00000571272 ; ENSP00000458174 ; ENSG00000074660 . [Q14162-3 ]
    GeneIDi 8578.
    KEGGi hsa:8578.
    UCSCi uc002fsy.2. human. [Q14162-3 ]
    uc002fsz.2. human. [Q14162-1 ]

    Organism-specific databases

    CTDi 8578.
    GeneCardsi GC17M001537.
    H-InvDB HIX0013404.
    HGNCi HGNC:16820. SCARF1.
    HPAi HPA035108.
    MIMi 607873. gene.
    neXtProti NX_Q14162.
    PharmGKBi PA38420.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG284054.
    HOGENOMi HOG000015093.
    HOVERGENi HBG099941.
    InParanoidi Q14162.
    OMAi PAYCVPP.
    OrthoDBi EOG77HDD8.
    PhylomeDBi Q14162.
    TreeFami TF332598.

    Enzyme and pathway databases

    Reactomei REACT_163813. Scavenging by Class F Receptors.

    Miscellaneous databases

    GenomeRNAii 8578.
    NextBioi 32179.
    PROi Q14162.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q14162.
    Bgeei Q14162.
    CleanExi HS_SCARF1.
    Genevestigatori Q14162.

    Family and domain databases

    InterProi IPR000742. EG-like_dom.
    IPR013032. EGF-like_CS.
    IPR002049. EGF_laminin.
    IPR009030. Growth_fac_rcpt_N_dom.
    [Graphical view ]
    Pfami PF12661. hEGF. 3 hits.
    PF00053. Laminin_EGF. 1 hit.
    [Graphical view ]
    SMARTi SM00181. EGF. 5 hits.
    [Graphical view ]
    SUPFAMi SSF57184. SSF57184. 1 hit.
    PROSITEi PS00022. EGF_1. 6 hits.
    PS01186. EGF_2. 6 hits.
    PS50026. EGF_3. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression cloning of a novel scavenger receptor from human endothelial cells."
      Adachi H., Tsujimoto M., Arai H., Inoue K.
      J. Biol. Chem. 272:31217-31220(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANTS VAL-425; ASP-639; TRP-662 AND SER-667.
      Tissue: Umbilical vein endothelial cell.
    2. "Characterization of the human gene encoding the scavenger receptor expressed by endothelial cell and its regulation by a novel transcription factor, endothelial zinc finger protein-2."
      Adachi H., Tsujimoto M.
      J. Biol. Chem. 277:24014-24021(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3; 4 AND 5), VARIANTS VAL-425; ASP-639 AND SER-667.
      Tissue: Peripheral blood leukocyte.
    3. "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1."
      Nagase T., Seki N., Tanaka A., Ishikawa K., Nomura N.
      DNA Res. 2:167-174(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS VAL-425; ASP-639; TRP-662 AND SER-667.
      Tissue: Bone marrow.
    4. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
      Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
      , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
      Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT VAL-425.
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS VAL-425; ASP-639 AND SER-667.
      Tissue: Testis.
    7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Platelet.

    Entry informationi

    Entry nameiSREC_HUMAN
    AccessioniPrimary (citable) accession number: Q14162
    Secondary accession number(s): A8MQ05
    , O43701, Q8NHD2, Q8NHD3, Q8NHD4, Q8NHD5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 23, 2002
    Last sequence update: November 2, 2010
    Last modified: October 1, 2014
    This is version 134 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 17
      Human chromosome 17: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3