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Protein
Submitted name:

2-oxoglutarate dehydrogenase E1 component

Gene

Bxe_A2812

Organism
Burkholderia xenovorans (strain LB400)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciBXEN266265:GJII-1670-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase E1 componentImported (EC:1.2.4.2Imported)
Gene namesi
ORF Names:Bxe_A2812Imported
OrganismiBurkholderia xenovorans (strain LB400)Imported
Taxonomic identifieri266265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000001817: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi266265.Bxe_A2812.

Structurei

3D structure databases

ProteinModelPortaliQ140T8.
SMRiQ140T8. Positions 90-944.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q140T8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKQFQSNSY LFGGNAPYVE EMYEAYLDNP ASVPENWRSY FDALQNVPAS
60 70 80 90 100
DGSNANDVAH GPIVESFAQR AKANAFIPRG AGGGEDLATA RKQVYVQSLI
110 120 130 140 150
GAYRFLGSQW ANLDPLKRRE RPAIPELEPA FYDFTEADMD QEFSATNLYF
160 170 180 190 200
GFERASLREI VKALRDTYCG TIGAEYMYIS DPEQKRWWKE KLESIRSTPN
210 220 230 240 250
FSNEKKKHIL NRLTAAEGLE RFLHTKYVGQ KRFSLEGGES FIASMDEVVR
260 270 280 290 300
HGGANGVQEI VIGMAHRGRL NVLVNTLGKM PADLFAEFEG KHVDDLPAGD
310 320 330 340 350
VKYHKGFSSD VSTEGGPVHL SLAFNPSHLE IVNPVVEGSA KARMDRRGDD
360 370 380 390 400
SGLQVLPVQI HGDAAFAGQG VVMETLNLAQ TRGYGTHGTL HIVINNQIGF
410 420 430 440 450
TTSDPRDSRS TLYCSDVVKM IEAPVLHVNG DDPEAVVLAT QLAIDFRMQF
460 470 480 490 500
HKDVVVDIVC FRKLGHNEQD TPAVTQPLMY KTIAKHPGTR ALYAEKLVQQ
510 520 530 540 550
GVITAADADE YVKAYRKAMD EGHHTVDPVL SNYKSKYAVD WVPFLNRKWT
560 570 580 590 600
DAADTAVPLA ELKRLAERIT TIPENFKVHP LVERVINDRR AMGRGEAKLD
610 620 630 640 650
WGMGEHLAFA SLVASGYAVR LTGQDSGRGT FTHRHAVLHD QNRERWNDGT
660 670 680 690 700
YVPLQNIAEG QAKFTVIDSV LSEEAVLGFE YGYSTAEPNT FVAWEAQFGD
710 720 730 740 750
FVNGAQVVID QFISSGEVKW GRVSGLTMLL PHGYEGQGPE HSSARIERFL
760 770 780 790 800
QLCADHNMQV VQPTTPAQIF HLLRRQMIRL FRKPLIVATP KSLLRHKEAV
810 820 830 840 850
SDLSELAKGA FQPILGEIDE AIDAKKVKRV VVCSGRVYYD LLAHRRESKS
860 870 880 890 900
NDVAIIRIEQ LYPFAHKQFE AEMKKYDNAT EVVWVQDEPQ NQGPWFYIEH
910 920 930 940 950
HLKDGMKEGQ KLAYSGRPAS ASPAVGYYAK HYEQQKALVE GAFGRLKSAS

IAK
Length:953
Mass (Da):106,455
Last modified:August 22, 2006 - v1
Checksum:i1756C87C808D799C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000270 Genomic DNA. Translation: ABE30151.1.
RefSeqiYP_558203.1. NC_007951.1.

Genome annotation databases

EnsemblBacteriaiABE30151; ABE30151; Bxe_A2812.
GeneIDi4003768.
KEGGibxe:Bxe_A2812.
PATRICi19328700. VBIBurXen52548_1679.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000270 Genomic DNA. Translation: ABE30151.1.
RefSeqiYP_558203.1. NC_007951.1.

3D structure databases

ProteinModelPortaliQ140T8.
SMRiQ140T8. Positions 90-944.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266265.Bxe_A2812.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE30151; ABE30151; Bxe_A2812.
GeneIDi4003768.
KEGGibxe:Bxe_A2812.
PATRICi19328700. VBIBurXen52548_1679.

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Enzyme and pathway databases

BioCyciBXEN266265:GJII-1670-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LB400Imported.

Entry informationi

Entry nameiQ140T8_BURXL
AccessioniPrimary (citable) accession number: Q140T8
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: February 4, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.