ID   Q140J5_PARXL            Unreviewed;       496 AA.
AC   Q140J5;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   SubName: Full=Aldehyde dehydrogenase (Acceptor) {ECO:0000313|EMBL:ABE30244.1};
DE            EC=1.2.5.2 {ECO:0000313|EMBL:ABE30244.1};
GN   ORFNames=Bxe_A2720 {ECO:0000313|EMBL:ABE30244.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE30244.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE30244.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE30244.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA   Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA   Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA   Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT   shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000270; ABE30244.1; -; Genomic_DNA.
DR   RefSeq; WP_011487941.1; NZ_CP008760.1.
DR   AlphaFoldDB; Q140J5; -.
DR   STRING; 266265.Bxe_A2720; -.
DR   KEGG; bxb:DR64_404; -.
DR   KEGG; bxe:Bxe_A2720; -.
DR   PATRIC; fig|266265.5.peg.1773; -.
DR   eggNOG; COG1012; Bacteria.
DR   OrthoDB; 6187633at2; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0047113; F:aldehyde dehydrogenase (quinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd07114; ALDH_DhaS; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          25..483
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        256
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   496 AA;  52885 MW;  381A9971D4230D22 CRC64;
     MAGVKELQAF PMVIGGERVP SASGVWLESI DPYTGEPWAK VPRGDATDAE AAVSAARKAL
     TTGAWHQLSA TQRGALLRRL ADLISRDWER LAEIEIRDNG KVISEVGPQI RYLAQYFHYY
     AGLADKIEGA VIPVDRPGML NYTRHEPVGV VVAITPWNSP LMLASWKIAP ALAAGCTVIL
     KPSEHTSVSS LVFSDLFDEA GFPPGVVNVV TGFGAEIGNA LVSHPDVAKV AFTGGDVAGQ
     AVYERAAAGL KRVTLELGGK SPHIVFDDAD LDGALAAAMD GVFSSSGQMC VAGSRLMLHD
     RIHDEFVARL LDRVRTLKLG APMNPATSIG PVTTQAQFER ILSYIDVAKQ EGARCLVGGV
     ASPEAEGGSG WFVAPTVFGD VKNDMRIARE EVFGPVLSII RFSTDDEAVH LANDSRYGLA
     SGIWTRDVGR AISVADRIQA GTVWVNTYRA VSAASPFGGM KRSGIGRENG QEAIMGFLQT
     KSIWISTTSR PVAAWS
//