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Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Paraburkholderia xenovorans (strain LB400)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei10NucleophileUniRule annotation1
Metal bindingi10MagnesiumUniRule annotation1
Metal bindingi12Magnesium; via carbonyl oxygenUniRule annotation1
Active sitei51Schiff-base intermediate with substrateUniRule annotation1
Metal bindingi184MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium, Metal-binding, Schiff base

Enzyme and pathway databases

BioCyciBXEN266265:G1G66-2349-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
Short name:
PhosphonataseUniRule annotation
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
Gene namesi
Name:phnXUniRule annotation
Ordered Locus Names:Bxeno_A2313
ORF Names:Bxe_A2117
OrganismiParaburkholderia xenovorans (strain LB400)
Taxonomic identifieri266265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeParaburkholderia
Proteomesi
  • UP000001817 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002845871 – 267Phosphonoacetaldehyde hydrolaseAdd BLAST267

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi266265.Bxe_A2117

Structurei

3D structure databases

ProteinModelPortaliQ13YI8
SMRiQ13YI8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108KAZ Bacteria
COG0637 LUCA
HOGENOMiHOG000217971
KOiK05306
OMAiKAVIFDW
OrthoDBiPOG091H05HY

Family and domain databases

CDDicd02586 HAD_PHN, 1 hit
Gene3Di1.10.150.240, 1 hit
3.40.50.1000, 2 hits
HAMAPiMF_01375 PhnX, 1 hit
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR023198 PGP-like_dom2
IPR006323 Phosphonoacetald_hydro
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01422 phosphonatase, 1 hit

Sequencei

Sequence statusi: Complete.

Q13YI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHVKAVIFD WAGTVVDYGS LAPMGAFVET FGQFGVPITI DEARGPMGMA
60 70 80 90 100
KRPHIAALMA LPRVAQAWTD KYGHAPDDAD IDAVYDVFVP KNIAVAASYS
110 120 130 140 150
SVIPGVADVA SALRGDDIRI GTTTGYTREI MAEIVPGAAA QGFSPDSIVC
160 170 180 190 200
TGDTAEGRPS PYMIYRTLPE LGVWRAKEAI KVDDTEVGIE EGINGGTWTV
210 220 230 240 250
GVSVSGNAFG MAEGDVKALA PDEFAWRRNA AIQKLQAAGA HYVIDSVADL
260
MPVVYDIEAR LARGERP
Length:267
Mass (Da):28,358
Last modified:August 22, 2006 - v1
Checksum:iAB50CDAD236F0F83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000270 Genomic DNA Translation: ABE30851.1
RefSeqiWP_011488465.1, NZ_CP008760.1

Genome annotation databases

EnsemblBacteriaiABE30851; ABE30851; Bxe_A2117
GeneIDi4005089
KEGGibxb:DR64_4272
bxe:Bxe_A2117
PATRICifig|266265.5.peg.2421

Similar proteinsi

Entry informationi

Entry nameiPHNX_PARXL
AccessioniPrimary (citable) accession number: Q13YI8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: August 22, 2006
Last modified: March 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health