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Q13YI8

- PHNX_BURXL

UniProt

Q13YI8 - PHNX_BURXL

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Protein

Phosphonoacetaldehyde hydrolase

Gene
phnX, Bxeno_A2313, Bxe_A2117
Organism
Burkholderia xenovorans (strain LB400)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in phosphonate degradation By similarity.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Binds 1 Mg2+ ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei10 – 101Nucleophile By similarity
Metal bindingi10 – 101Magnesium By similarity
Metal bindingi12 – 121Magnesium; via carbonyl oxygen By similarity
Active sitei51 – 511Schiff-base intermediate with substrate By similarity
Metal bindingi184 – 1841Magnesium By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphonoacetaldehyde hydrolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. organic phosphonate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding, Schiff base

Enzyme and pathway databases

BioCyciBXEN266265:GJII-2415-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolase (EC:3.11.1.1)
Short name:
Phosphonatase
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolase
Gene namesi
Name:phnX
Ordered Locus Names:Bxeno_A2313
ORF Names:Bxe_A2117
OrganismiBurkholderia xenovorans (strain LB400)
Taxonomic identifieri266265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000001817: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 267267Phosphonoacetaldehyde hydrolaseUniRule annotationPRO_0000284587Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi266265.Bxe_A2117.

Structurei

3D structure databases

ProteinModelPortaliQ13YI8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0637.
HOGENOMiHOG000217971.
KOiK05306.
OMAiDERNVER.
OrthoDBiEOG6ZH2FH.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX.
InterProiIPR023214. HAD-like_dom.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q13YI8-1 [UniParc]FASTAAdd to Basket

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MKHVKAVIFD WAGTVVDYGS LAPMGAFVET FGQFGVPITI DEARGPMGMA    50
KRPHIAALMA LPRVAQAWTD KYGHAPDDAD IDAVYDVFVP KNIAVAASYS 100
SVIPGVADVA SALRGDDIRI GTTTGYTREI MAEIVPGAAA QGFSPDSIVC 150
TGDTAEGRPS PYMIYRTLPE LGVWRAKEAI KVDDTEVGIE EGINGGTWTV 200
GVSVSGNAFG MAEGDVKALA PDEFAWRRNA AIQKLQAAGA HYVIDSVADL 250
MPVVYDIEAR LARGERP 267
Length:267
Mass (Da):28,358
Last modified:August 22, 2006 - v1
Checksum:iAB50CDAD236F0F83
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000270 Genomic DNA. Translation: ABE30851.1.
RefSeqiWP_011488465.1. NC_007951.1.
YP_558903.1. NC_007951.1.

Genome annotation databases

EnsemblBacteriaiABE30851; ABE30851; Bxe_A2117.
GeneIDi4005089.
KEGGibxe:Bxe_A2117.
PATRICi19330202. VBIBurXen52548_2421.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000270 Genomic DNA. Translation: ABE30851.1 .
RefSeqi WP_011488465.1. NC_007951.1.
YP_558903.1. NC_007951.1.

3D structure databases

ProteinModelPortali Q13YI8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266265.Bxe_A2117.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE30851 ; ABE30851 ; Bxe_A2117 .
GeneIDi 4005089.
KEGGi bxe:Bxe_A2117.
PATRICi 19330202. VBIBurXen52548_2421.

Phylogenomic databases

eggNOGi COG0637.
HOGENOMi HOG000217971.
KOi K05306.
OMAi DERNVER.
OrthoDBi EOG6ZH2FH.

Enzyme and pathway databases

BioCyci BXEN266265:GJII-2415-MONOMER.

Family and domain databases

Gene3Di 1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPi MF_01375. PhnX.
InterProi IPR023214. HAD-like_dom.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view ]
Pfami PF13419. HAD_2. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01422. phosphonatase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LB400.

Entry informationi

Entry nameiPHNX_BURXL
AccessioniPrimary (citable) accession number: Q13YI8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: August 22, 2006
Last modified: September 3, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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