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Q13YI8 (PHNX_BURXL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphonoacetaldehyde hydrolase

Short name=Phosphonatase
EC=3.11.1.1
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolase
Gene names
Name:phnX
Ordered Locus Names:Bxeno_A2313
ORF Names:Bxe_A2117
OrganismBurkholderia xenovorans (strain LB400) [Complete proteome] [HAMAP]
Taxonomic identifier266265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in phosphonate degradation By similarity. HAMAP-Rule MF_01375

Catalytic activity

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate. HAMAP-Rule MF_01375

Cofactor

Binds 1 Mg2+ ion per subunit By similarity. HAMAP-Rule MF_01375

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01375

Sequence similarities

Belongs to the HAD-like hydrolase superfamily. PhnX family.

Ontologies

Keywords
   LigandMagnesium
Metal-binding
Schiff base
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processorganic phosphonate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphonoacetaldehyde hydrolase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Phosphonoacetaldehyde hydrolase HAMAP-Rule MF_01375
PRO_0000284587

Sites

Active site101Nucleophile By similarity
Active site511Schiff-base intermediate with substrate By similarity
Metal binding101Magnesium By similarity
Metal binding121Magnesium; via carbonyl oxygen By similarity
Metal binding1841Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q13YI8 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: AB50CDAD236F0F83

FASTA26728,358
        10         20         30         40         50         60 
MKHVKAVIFD WAGTVVDYGS LAPMGAFVET FGQFGVPITI DEARGPMGMA KRPHIAALMA 

        70         80         90        100        110        120 
LPRVAQAWTD KYGHAPDDAD IDAVYDVFVP KNIAVAASYS SVIPGVADVA SALRGDDIRI 

       130        140        150        160        170        180 
GTTTGYTREI MAEIVPGAAA QGFSPDSIVC TGDTAEGRPS PYMIYRTLPE LGVWRAKEAI 

       190        200        210        220        230        240 
KVDDTEVGIE EGINGGTWTV GVSVSGNAFG MAEGDVKALA PDEFAWRRNA AIQKLQAAGA 

       250        260 
HYVIDSVADL MPVVYDIEAR LARGERP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000270 Genomic DNA. Translation: ABE30851.1.
RefSeqYP_558903.1. NC_007951.1.

3D structure databases

ProteinModelPortalQ13YI8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266265.Bxe_A2117.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE30851; ABE30851; Bxe_A2117.
GeneID4005089.
KEGGbxe:Bxe_A2117.
PATRIC19330202. VBIBurXen52548_2421.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0637.
HOGENOMHOG000217971.
KOK05306.
OMADERNVER.
OrthoDBEOG6ZH2FH.

Enzyme and pathway databases

BioCycBXEN266265:GJII-2415-MONOMER.

Family and domain databases

Gene3D1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPMF_01375. PhnX.
InterProIPR023214. HAD-like_dom.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMSSF56784. SSF56784. 1 hit.
TIGRFAMsTIGR01422. phosphonatase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePHNX_BURXL
AccessionPrimary (citable) accession number: Q13YI8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: August 22, 2006
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families