Q13Y97 (FENR_BURXL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2

Gene names

Ordered Locus Names:	Bxeno_A2404
ORF Names:	Bxe_A2024

Organism

Burkholderia xenovorans (strain LB400) [Complete proteome] [HAMAP]

Taxonomic identifier

266265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length	353 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity. HAMAP MF_01685
Subunit structure	Homodimer By similarity. HAMAP MF_01685
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 353	353	Ferredoxin--NADP reductase HAMAP MF_01685		PRO_0000364815
Sites
	Binding site	47	1	FAD By similarity
	Binding site	55	1	FAD By similarity
	Binding site	60	1	FAD By similarity
	Binding site	100	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	135	1	FAD; via amide nitrogen By similarity
	Binding site	299	1	FAD By similarity
	Binding site	340	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q13Y97 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 8CA1000C83741461	FASTA	353	37,587
	10 20 30 40 50 60 MSSAANLPSP SPSPPIRTDV LIVGAGPVGL FAAFEAGVIG LSCQIVDGLD KVGGQCIELY 70 80 90 100 110 120 PDKPIYDIPA IPSCTARELV ERLLAQCRPF DPPIHLEQRV ESVEQGGDGR WTVRTDRGLV 130 140 150 160 170 180 FDVAAILLAA GNGAFVPQKL ALAEAVPLES RHVHYSVPRL ADFAGKTVVV AGGGDSALDW 190 200 210 220 230 240 ALALRKVARR VTLVHRRSGF SAADSSVESM RRAVEAGEMD FVVGAIAGLD VEDDALKSIT 250 260 270 280 290 300 LRHIEGETQL AAEHLVALYG LVADLGPIAQ WGLSIHGGRV DVDTSNYESS RPGIFAVGDI 310 320 330 340 350 AHYPNKQKLI LSGFHEASLA LRKAYSYAYP EKKRVHVHSS YDAKLAEKVS AAG

References

[1]

"Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility." Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L., Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J., Parnell J.J. , Ramette A., Richardson P., Seeger M., Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M. Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006) [PubMed: 17030797] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LB400.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000270 Genomic DNA. Translation: ABE30942.1.
RefSeq	YP_558994.1. NC_007951.1.
3D structure databases
ProteinModelPortal	Q13Y97.
ModBase	Search...
Protein-protein interaction databases
STRING	Q13Y97.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4003339.
GenomeReviews	Gene locus Bxeno_A2404 in contig CP000270_GR.
KEGG	bxe:Bxe_A2024.
PATRIC	19330400. VBIBurXen52548_2520.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG669726.
OMA	YPNKQKL.
ProtClustDB	CLSK896839.
Family and domain databases
HAMAP	MF_01685. FENR2. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR022890. Fd--NADP_Rdtase_type_2. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
KO	K00384.
PANTHER	PTHR22912:SF53. PTHR22912:SF53. 1 hit.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProtoNet	Search...

Entry information

Entry name

FENR_BURXL

Accession

Primary (citable) accession number: Q13Y97

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	August 22, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program