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Q13W85 (UPPP2_BURXL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 2

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 2
Undecaprenyl pyrophosphate phosphatase 2
Gene names
Name:uppP2
Ordered Locus Names:Bxeno_A3116
ORF Names:Bxe_A1299
OrganismBurkholderia xenovorans (strain LB400) [Complete proteome] [HAMAP]
Taxonomic identifier266265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Undecaprenyl-diphosphatase 2 HAMAP-Rule MF_01006
PRO_0000250231

Regions

Transmembrane5 – 2723Helical; Potential
Transmembrane44 – 6421Helical; Potential
Transmembrane87 – 10721Helical; Potential
Transmembrane114 – 13421Helical; Potential
Transmembrane150 – 17021Helical; Potential
Transmembrane190 – 21021Helical; Potential
Transmembrane218 – 23821Helical; Potential
Transmembrane251 – 27121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q13W85 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: A81481C5549D5610

FASTA27630,268
        10         20         30         40         50         60 
MNLSFLIFLS VLQGVTELFP VSSLGHTLLV PALFGMHIDK HAPQLLPFLV ALHLGTAFAL 

        70         80         90        100        110        120 
LWYFRKRWCA LVRGFFASFG GRRNDDAHMM WALIIGTIPA GLVGLLLEKR LERIFHDLRI 

       130        140        150        160        170        180 
VAIALIVNGV LLWFGDRLQR TRAHQAPEKL TFRQAFFVGL AQIGALIPGF SRSGLTMIAG 

       190        200        210        220        230        240 
NAAGLTAEKA AEFSFLLGTP IIFAAGVLEL PKLFHAPGQL ADALLGGVLT AIAAYLSVRF 

       250        260        270 
LMRYFEGRGR LASFGVYCVI AGIVFLGWFL LHPQPV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000270 Genomic DNA. Translation: ABE31654.1.
RefSeqYP_559706.1. NC_007951.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266265.Bxe_A1299.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE31654; ABE31654; Bxe_A1299.
GeneID4005068.
KEGGbxe:Bxe_A1299.
PATRIC19331934. VBIBurXen52548_3276.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMASDIMRIA.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycBXEN266265:GJII-3239-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP2_BURXL
AccessionPrimary (citable) accession number: Q13W85
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: August 22, 2006
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families