Reviewed,
UniProtKB/Swiss-Prot Q13V64 (F16A1_BURXL)
Last modified
January 19, 2010.
Version 30.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Fructose-1,6-bisphosphatase class 1 1 Short name=FBPase class 1 1 EC=3.1.3.11 Alternative name(s): D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1 | ||||||
| Gene names |
| ||||||
| Organism | Burkholderia xenovorans (strain LB400) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 266265 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia |
Protein attributes
| Sequence length | 338 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855 |
| Cofactor | Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855 |
| Pathway | |
| Subunit structure | Homotetramer By similarity. HAMAP MF_01855 |
| Subcellular location | Cytoplasm Potential HAMAP MF_01855. |
| Sequence similarities | Belongs to the FBPase class 1 family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Carbohydrate metabolism |
| Cellular component | Cytoplasm |
| Ligand | Magnesium Metal-binding |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | carbohydrate biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 338 | 338 | Fructose-1,6-bisphosphatase class 1 1 HAMAP MF_01855 | PRO_0000364506 | |||||
Regions | |||||||||
| Region | 119 – 122 | 4 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Metal binding | 94 | 1 | Magnesium 1 By similarity | ||||||
| Metal binding | 116 | 1 | Magnesium 1 By similarity | ||||||
| Metal binding | 116 | 1 | Magnesium 2 By similarity | ||||||
| Metal binding | 118 | 1 | Magnesium 1; via carbonyl oxygen By similarity | ||||||
| Metal binding | 119 | 1 | Magnesium 2 By similarity | ||||||
| Metal binding | 282 | 1 | Magnesium 2 By similarity | ||||||
| Binding site | 210 | 1 | Substrate By similarity | ||||||
| Binding site | 276 | 1 | Substrate By similarity | ||||||
Sequences
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References
| [1] | "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility." Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L., Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J., Parnell J.J. Tiedje J.M.Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006) [PubMed: 17030797] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000270 Genomic DNA. Translation: ABE32025.1. |
| RefSeq | YP_560077.1. |
3D structure databases | |
| SMR | Q13V64. Positions 7-337. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 4002901. |
| GenomeReviews | Gene locus Bxeno_A3487 in contig CP000270_GR. |
| KEGG | bxe:Bxe_A0920. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG731261. |
| OMA | HWEAPVQ. |
Family and domain databases | |
| HAMAP | MF_01855. FBPase_class1. [Tree] |
| InterPro | IPR000146. Fructose_bisphosphatase. [Graphical view] |
| PANTHER | PTHR11556. In_FB_phphtase. 1 hit. |
| Pfam | PF00316. FBPase. 1 hit. [Graphical view] |
| PRINTS | PR00115. F16BPHPHTASE. |
| PROSITE | PS00124. FBPASE. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | F16A1_BURXL | ||||||||
| Accession | Primary (citable) accession number: Q13V64 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


