SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q13V14

- TRMB_BURXL

UniProt

Q13V14 - TRMB_BURXL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene
trmB, Bxeno_A3537, Bxe_A0859
Organism
Burkholderia xenovorans (strain LB400)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei90 – 901S-adenosyl-L-methionine By similarity
Binding sitei115 – 1151S-adenosyl-L-methionine By similarity
Binding sitei142 – 1421S-adenosyl-L-methionine By similarity
Active sitei165 – 1651 By similarity
Binding sitei165 – 1651S-adenosyl-L-methionine By similarity
Binding sitei169 – 1691Substrate By similarity
Binding sitei201 – 2011Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciBXEN266265:GJII-3689-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:Bxeno_A3537
ORF Names:Bxe_A0859
OrganismiBurkholderia xenovorans (strain LB400)
Taxonomic identifieri266265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000001817: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 260260tRNA (guanine-N(7)-)-methyltransferaseUniRule annotationPRO_0000288131Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266265.Bxe_A0859.

Structurei

3D structure databases

ProteinModelPortaliQ13V14.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni236 – 2394Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000073968.
KOiK03439.
OMAiQDNFLCC.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q13V14-1 [UniParc]FASTAAdd to Basket

« Hide

MIHDPNDAGL PDQLPTPSSE AENSPAGDTT PPEEALHRRR IRSFVTRAGR    50
VSTGQRRAMD ELGPRFVVPF APQQPDWNSV FGREAPRVLE IGFGMGATTA 100
EIASHRPDED FLGVEVHEPG VGALLKLMGE QNLSNIRIIQ HDAVEVLEQM 150
IAPDSLDGVH IFFPDPWHKA RHHKRRLIQP KFVALLVSRL KPGAYLHCAT 200
DWQNYAEQML EVLGAEPSLK NTADGYAPRP EYRPVTKFER RGLRLGHGVW 250
DLVFRKRGAG 260
Length:260
Mass (Da):29,078
Last modified:May 29, 2007 - v2
Checksum:i433D83F9E3C279D8
GO

Sequence cautioni

The sequence ABE32075.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000270 Genomic DNA. Translation: ABE32075.1. Different initiation.
RefSeqiYP_560127.1. NC_007951.1.

Genome annotation databases

EnsemblBacteriaiABE32075; ABE32075; Bxe_A0859.
GeneIDi4002874.
KEGGibxe:Bxe_A0859.
PATRICi19332855. VBIBurXen52548_3723.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000270 Genomic DNA. Translation: ABE32075.1 . Different initiation.
RefSeqi YP_560127.1. NC_007951.1.

3D structure databases

ProteinModelPortali Q13V14.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266265.Bxe_A0859.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE32075 ; ABE32075 ; Bxe_A0859 .
GeneIDi 4002874.
KEGGi bxe:Bxe_A0859.
PATRICi 19332855. VBIBurXen52548_3723.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000073968.
KOi K03439.
OMAi QDNFLCC.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci BXEN266265:GJII-3689-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LB400.

Entry informationi

Entry nameiTRMB_BURXL
AccessioniPrimary (citable) accession number: Q13V14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: June 11, 2014
This is version 52 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi