ID   Q13SC7_PARXL            Unreviewed;       565 AA.
AC   Q13SC7;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   27-MAR-2024, entry version 108.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer, Pas/Pac sensor {ECO:0000313|EMBL:ABE33012.1};
GN   ORFNames=Bxe_B2984 {ECO:0000313|EMBL:ABE33012.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE33012.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE33012.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE33012.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA   Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA   Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA   Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT   shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000271; ABE33012.1; -; Genomic_DNA.
DR   RefSeq; WP_011490401.1; NZ_CP008762.1.
DR   AlphaFoldDB; Q13SC7; -.
DR   STRING; 266265.Bxe_B2984; -.
DR   KEGG; bxb:DR64_5314; -.
DR   KEGG; bxe:Bxe_B2984; -.
DR   PATRIC; fig|266265.5.peg.4705; -.
DR   eggNOG; COG0840; Bacteria.
DR   eggNOG; COG3829; Bacteria.
DR   OrthoDB; 9806477at2; -.
DR   Proteomes; UP000001817; Chromosome 2.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        170..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          21..60
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          216..268
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          273..502
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          523..565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        529..543
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        549..565
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   565 AA;  60158 MW;  E6F1F21862029DDE CRC64;
     MRNNQPVTGH EYEFPSLQML VSATDLTGRI QYCNPAFIAV SGFTRDELIG QPHNLIRHPD
     MPREAFADMW ATIRAGRPWT ALVKNRRKNG DHYWVHANVT PVVEKGTVVG YLSVRVKPER
     DAVRSAEALY ARMRTGEARG IKLRRGVVVR TGLPGRLQAL MRLPVATRAA TGYAITSLAL
     LLTGLAAWQG APPVQFWIAF GVTSAVGLVS WQLLKRQLAA PIREMSGFAT RLAAGDLTAD
     LHIARHDDLG EVLQALNQLK ANLAAIVYDV RAQITGMLDN AREISSGNVD LARRTELQAA
     SLEETAATME QLTTTVQANA DATVRALDLA RDAQAAAAVG GKIAGQVEQT MAGITAASQR
     IADITSVIDG IAFQTNILAL NAAVEAARAG EAGRSFAVVA SEVRMLAQRC AASSKEIKSV
     VEASATEVAA GTELVARTTS QMRVIDEAVG RVSSIIVDVA NASSEQAEGI RQVNQAVSHL
     DGATQQNAAL VEQAAATAQR LAEQADVLDE AVRLFSVAHA APAQRAGGAT RSRTLTSDAA
     QTGDIKRHSA PAVARETEHD EATMI
//