Q13KK3 (Q13KK3_BURXL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 3 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 3 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 3 HAMAP MF_01401

Gene names

Name:	msrA3 HAMAP MF_01401
Ordered Locus Names:	Bxeno_B2418
ORF Names:	Bxe_B0562 EMBL ABE35386.1

Organism

Burkholderia xenovorans (strain LB400) [Complete proteome] [HAMAP] EMBL ABE35386.1

Taxonomic identifier

266265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL ABE35386.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	14	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q13KK3 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: F91FDB5F325BB575	FASTA	168	19,124
	10 20 30 40 50 60 MTTQTETALL AGGCFWGMQD LLRRYPGVLS TRVGYTGGDV PNATYRNHGT HAEALEVVFD 70 80 90 100 110 120 PRQISYRQIL EFFFQIHDPT TKNRQGNDVG TSYRSAIFYL DDEQKRVAEN TVADVEASDL 130 140 150 160 WPGKVVTEIA PAGPFWEAEP EHQDYLERIP NGYTCHFVRP DWKLPKRG

References

[1]

"Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility." Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L., Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J., Parnell J.J. , Ramette A., Richardson P., Seeger M., Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M. Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006) [PubMed: 17030797] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000271 Genomic DNA. Translation: ABE35386.1.
RefSeq	YP_554736.1. NC_007952.1.
3D structure databases
ProteinModelPortal	Q13KK3.
SMR	Q13KK3. Positions 3-167.
ModBase	Search...
Protein-protein interaction databases
STRING	Q13KK3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4008949.
GenomeReviews	Gene locus Bxeno_B2418 in contig CP000271_GR.
KEGG	bxe:Bxe_B0562.
PATRIC	19339944. VBIBurXen52548_7230.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG748152.
OMA	YRQILEF.
PhylomeDB	Q13KK3.
ProtClustDB	PRK14054.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q13KK3_BURXL

Accession

Primary (citable) accession number: Q13KK3

Entry history

Integrated into UniProtKB/TrEMBL:	August 22, 2006
Last sequence update:	August 22, 2006
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)