ID   Q13K16_PARXL            Unreviewed;       390 AA.
AC   Q13K16;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   27-MAR-2024, entry version 123.
DE   SubName: Full=Alanine racemase {ECO:0000313|EMBL:ABE35573.1};
DE            EC=5.1.1.1 {ECO:0000313|EMBL:ABE35573.1};
GN   ORFNames=Bxe_B0373 {ECO:0000313|EMBL:ABE35573.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE35573.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE35573.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE35573.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA   Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA   Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA   Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT   shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR600821-50};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000271; ABE35573.1; -; Genomic_DNA.
DR   RefSeq; WP_011492848.1; NZ_CP008762.1.
DR   AlphaFoldDB; Q13K16; -.
DR   STRING; 266265.Bxe_B0373; -.
DR   KEGG; bxb:DR64_5713; -.
DR   KEGG; bxe:Bxe_B0373; -.
DR   PATRIC; fig|266265.5.peg.7420; -.
DR   eggNOG; COG0787; Bacteria.
DR   OrthoDB; 2081341at2; -.
DR   Proteomes; UP000001817; Chromosome 2.
DR   GO; GO:0008784; F:alanine racemase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006522; P:alanine metabolic process; IEA:InterPro.
DR   CDD; cd00430; PLPDE_III_AR; 1.
DR   Gene3D; 3.20.20.10; Alanine racemase; 1.
DR   InterPro; IPR000821; Ala_racemase.
DR   InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR   InterPro; IPR011079; Ala_racemase_C.
DR   InterPro; IPR001608; Ala_racemase_N.
DR   InterPro; IPR029066; PLP-binding_barrel.
DR   NCBIfam; TIGR00492; alr; 1.
DR   PANTHER; PTHR30511; ALANINE RACEMASE; 1.
DR   PANTHER; PTHR30511:SF0; ALANINE RACEMASE, CATABOLIC-RELATED; 1.
DR   Pfam; PF00842; Ala_racemase_C; 1.
DR   Pfam; PF01168; Ala_racemase_N; 1.
DR   PRINTS; PR00992; ALARACEMASE.
DR   SMART; SM01005; Ala_racemase_C; 1.
DR   SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR   SUPFAM; SSF51419; PLP-binding barrel; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ABE35573.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR600821-50}.
FT   DOMAIN          252..381
FT                   /note="Alanine racemase C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01005"
FT   MOD_RES         52
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600821-50"
SQ   SEQUENCE   390 AA;  41663 MW;  6DE8B221C58DDFDA CRC64;
     MSVPIIEPAA DAQGVRLLRP SWAELDYGAV AANLAVAREQ VGRATKIYFV CKGDGFGFGA
     AKVARLAAQA GVDGFCVGSP EEGVTIRRAG IDRDILLFAS TLPEDAAQVA ALGLTVTIQS
     RESLHAFINA GVAVDAFLEI DPGFGRFGFL PSQWQAAFAA LRDQSTVRLK GVYTHLSSPE
     SEDVTRQQAG VFDAALADAR AAGFDNLTTM LASSRVMLAH PHLAYQAVDP GRLLYGALDA
     DWMARAPLRP MLRAVRGRII HVQEHPAGAT LGIGYAEPIR LERGVRIGVV PIGFWDGLNH
     VPPLGRVLVH GQPARILGRR SFQHTVIDIT EIAAARTGSV VTLLGQDGDQ SITIDEMAET
     LRLPVMELIP RLARSLPHVE VKTADPAGNN
//