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Q13K16

- Q13K16_BURXL

UniProt

Q13K16 - Q13K16_BURXL

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Protein
Alanine racemase
Gene
Bxe_B0373
Organism
Burkholderia xenovorans (strain LB400)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei52 – 521Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei146 – 1461Substrate By similarityUniRule annotation
Active sitei275 – 2751Proton acceptor; specific for L-alanine By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciBXEN266265:GJII-7278-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
ORF Names:Bxe_B0373Imported
OrganismiBurkholderia xenovorans (strain LB400)Imported
Taxonomic identifieri266265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000001817: Chromosome 2

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei52 – 521N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi266265.Bxe_B0373.

Structurei

3D structure databases

ProteinModelPortaliQ13K16.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000118797.
KOiK01775.
OMAiKIYFVCK.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

Q13K16-1 [UniParc]FASTAAdd to Basket

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MSVPIIEPAA DAQGVRLLRP SWAELDYGAV AANLAVAREQ VGRATKIYFV    50
CKGDGFGFGA AKVARLAAQA GVDGFCVGSP EEGVTIRRAG IDRDILLFAS 100
TLPEDAAQVA ALGLTVTIQS RESLHAFINA GVAVDAFLEI DPGFGRFGFL 150
PSQWQAAFAA LRDQSTVRLK GVYTHLSSPE SEDVTRQQAG VFDAALADAR 200
AAGFDNLTTM LASSRVMLAH PHLAYQAVDP GRLLYGALDA DWMARAPLRP 250
MLRAVRGRII HVQEHPAGAT LGIGYAEPIR LERGVRIGVV PIGFWDGLNH 300
VPPLGRVLVH GQPARILGRR SFQHTVIDIT EIAAARTGSV VTLLGQDGDQ 350
SITIDEMAET LRLPVMELIP RLARSLPHVE VKTADPAGNN 390
Length:390
Mass (Da):41,663
Last modified:August 22, 2006 - v1
Checksum:i6DE8B221C58DDFDA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000271 Genomic DNA. Translation: ABE35573.1.
RefSeqiWP_011492848.1. NC_007952.1.
YP_554923.1. NC_007952.1.

Genome annotation databases

EnsemblBacteriaiABE35573; ABE35573; Bxe_B0373.
GeneIDi4009138.
KEGGibxe:Bxe_B0373.
PATRICi19340324. VBIBurXen52548_7420.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000271 Genomic DNA. Translation: ABE35573.1 .
RefSeqi WP_011492848.1. NC_007952.1.
YP_554923.1. NC_007952.1.

3D structure databases

ProteinModelPortali Q13K16.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266265.Bxe_B0373.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE35573 ; ABE35573 ; Bxe_B0373 .
GeneIDi 4009138.
KEGGi bxe:Bxe_B0373.
PATRICi 19340324. VBIBurXen52548_7420.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000118797.
KOi K01775.
OMAi KIYFVCK.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci BXEN266265:GJII-7278-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LB400Imported.

Entry informationi

Entry nameiQ13K16_BURXL
AccessioniPrimary (citable) accession number: Q13K16
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: September 3, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi