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Q13K16

- Q13K16_BURXL

UniProt

Q13K16 - Q13K16_BURXL

Protein

Alanine racemase

Gene

Bxe_B0373

Organism
Burkholderia xenovorans (strain LB400)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (22 Aug 2006)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei52 – 521Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei146 – 1461SubstrateUniRule annotation
    Active sitei275 – 2751Proton acceptor; specific for L-alanineUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciBXEN266265:GJII-7278-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    ORF Names:Bxe_B0373Imported
    OrganismiBurkholderia xenovorans (strain LB400)Imported
    Taxonomic identifieri266265 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
    ProteomesiUP000001817: Chromosome 2

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei52 – 521N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi266265.Bxe_B0373.

    Structurei

    3D structure databases

    ProteinModelPortaliQ13K16.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000118797.
    KOiK01775.
    OMAiKIYFVCK.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q13K16-1 [UniParc]FASTAAdd to Basket

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    MSVPIIEPAA DAQGVRLLRP SWAELDYGAV AANLAVAREQ VGRATKIYFV    50
    CKGDGFGFGA AKVARLAAQA GVDGFCVGSP EEGVTIRRAG IDRDILLFAS 100
    TLPEDAAQVA ALGLTVTIQS RESLHAFINA GVAVDAFLEI DPGFGRFGFL 150
    PSQWQAAFAA LRDQSTVRLK GVYTHLSSPE SEDVTRQQAG VFDAALADAR 200
    AAGFDNLTTM LASSRVMLAH PHLAYQAVDP GRLLYGALDA DWMARAPLRP 250
    MLRAVRGRII HVQEHPAGAT LGIGYAEPIR LERGVRIGVV PIGFWDGLNH 300
    VPPLGRVLVH GQPARILGRR SFQHTVIDIT EIAAARTGSV VTLLGQDGDQ 350
    SITIDEMAET LRLPVMELIP RLARSLPHVE VKTADPAGNN 390
    Length:390
    Mass (Da):41,663
    Last modified:August 22, 2006 - v1
    Checksum:i6DE8B221C58DDFDA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000271 Genomic DNA. Translation: ABE35573.1.
    RefSeqiWP_011492848.1. NC_007952.1.
    YP_554923.1. NC_007952.1.

    Genome annotation databases

    EnsemblBacteriaiABE35573; ABE35573; Bxe_B0373.
    GeneIDi4009138.
    KEGGibxe:Bxe_B0373.
    PATRICi19340324. VBIBurXen52548_7420.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000271 Genomic DNA. Translation: ABE35573.1 .
    RefSeqi WP_011492848.1. NC_007952.1.
    YP_554923.1. NC_007952.1.

    3D structure databases

    ProteinModelPortali Q13K16.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 266265.Bxe_B0373.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE35573 ; ABE35573 ; Bxe_B0373 .
    GeneIDi 4009138.
    KEGGi bxe:Bxe_B0373.
    PATRICi 19340324. VBIBurXen52548_7420.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000118797.
    KOi K01775.
    OMAi KIYFVCK.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci BXEN266265:GJII-7278-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LB400Imported.

    Entry informationi

    Entry nameiQ13K16_BURXL
    AccessioniPrimary (citable) accession number: Q13K16
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 22, 2006
    Last sequence update: August 22, 2006
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3