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Protein

Glutamate decarboxylase

Gene

Bxe_C0551

Organism
Burkholderia xenovorans (strain LB400)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciBXEN266265:GJII-8205-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:Bxe_C0551Imported
OrganismiBurkholderia xenovorans (strain LB400)Imported
Taxonomic identifieri266265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000001817 Componenti: Chromosome 3

Interactioni

Protein-protein interaction databases

STRINGi266265.Bxe_C0551.

Structurei

3D structure databases

ProteinModelPortaliQ13HI9.
SMRiQ13HI9. Positions 24-448.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiHINRVAT.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q13HI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFLKSPPPT PDAVADEYAA MISGSSLPKY RIPEASSDRR AVFDLVRDEL
60 70 80 90 100
FMDGNSRQNV ATFCTTYADD EVRRLMDLSI DKNMIDKDEY PQTAEIEMRC
110 120 130 140 150
VHMLADLWHA TKSWKTTGCS TTGSSEACML GGLALKWQWK KRREAQGKPT
160 170 180 190 200
GKPNFVCGPV QVCWAKFARY FDVEMRQVPL SGDATGLRPE DLAQYCDENT
210 220 230 240 250
IGVVATLGIT FTCVYEPVKA LAGALDALQA NVGLDIPIHV DAASGGFVAP
260 270 280 290 300
FIQPDLEWDF SVPRVKSINA SGHKYGLAPL GVGWIVWRST QDLPDELIFR
310 320 330 340 350
VDYLGGDMPT FALNFSRPAG QIIAQYYMLL RLGREGYRHI QQECADTAQA
360 370 380 390 400
LADGLAKIDA LDMIYDGRGA LPAVCYKLKH PDTAGFTLFD LSDRVRMRGW
410 420 430 440 450
QIASYELPAG REDTIVQRVL IRRGVTRDMA AMLLEDIKHA IAHLTKNPVP
460
NSTAGPTFHH D
Length:461
Mass (Da):51,118
Last modified:August 22, 2006 - v1
Checksum:i632CBE2C37B4513E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000272 Genomic DNA. Translation: ABE36450.1.
RefSeqiWP_011493706.1. NC_007953.1.
YP_555800.1. NC_007953.1.

Genome annotation databases

EnsemblBacteriaiABE36450; ABE36450; Bxe_C0551.
GeneIDi4010065.
KEGGibxe:Bxe_C0551.
PATRICi19342108. VBIBurXen52548_8312.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000272 Genomic DNA. Translation: ABE36450.1.
RefSeqiWP_011493706.1. NC_007953.1.
YP_555800.1. NC_007953.1.

3D structure databases

ProteinModelPortaliQ13HI9.
SMRiQ13HI9. Positions 24-448.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266265.Bxe_C0551.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE36450; ABE36450; Bxe_C0551.
GeneIDi4010065.
KEGGibxe:Bxe_C0551.
PATRICi19342108. VBIBurXen52548_8312.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiHINRVAT.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciBXEN266265:GJII-8205-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LB400Imported.

Entry informationi

Entry nameiQ13HI9_BURXL
AccessioniPrimary (citable) accession number: Q13HI9
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: February 4, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.