ID   Q13FX9_PARXL            Unreviewed;       442 AA.
AC   Q13FX9;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=ABC antibiotic efflux pump, outer membrane protein, TolC family {ECO:0000313|EMBL:ABE37010.1};
GN   ORFNames=Bxe_C1145 {ECO:0000313|EMBL:ABE37010.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE37010.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE37010.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE37010.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA   Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA   Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA   Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT   shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC       family. {ECO:0000256|ARBA:ARBA00007613}.
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DR   EMBL; CP000272; ABE37010.1; -; Genomic_DNA.
DR   RefSeq; WP_011494257.1; NZ_CP008761.1.
DR   AlphaFoldDB; Q13FX9; -.
DR   STRING; 266265.Bxe_C1145; -.
DR   KEGG; bxb:DR64_8655; -.
DR   KEGG; bxe:Bxe_C1145; -.
DR   PATRIC; fig|266265.5.peg.8899; -.
DR   eggNOG; COG1538; Bacteria.
DR   OrthoDB; 9813458at2; -.
DR   Proteomes; UP000001817; Chromosome 3.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR   InterPro; IPR003423; OMP_efflux.
DR   InterPro; IPR010130; T1SS_OMP_TolC.
DR   NCBIfam; TIGR01844; type_I_sec_TolC; 1.
DR   PANTHER; PTHR30026; OUTER MEMBRANE PROTEIN TOLC; 1.
DR   PANTHER; PTHR30026:SF15; OUTER MEMBRANE PROTEIN TOLC; 1.
DR   Pfam; PF02321; OEP; 2.
DR   SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE   3: Inferred from homology;
KW   Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..442
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004181964"
SQ   SEQUENCE   442 AA;  47360 MW;  EDE5C6CA7CC60D35 CRC64;
     MKIATPFLLC SLVFPVLAHG SVDLVDAVDA AFGYDSGISS ARNVQSAGHE KRWQGIAALL
     PNAQFEAHGS KQDQPGAAYA AGVRKHGYSF SVVQPIFDGS RIAEFKRGKV LSEQADIDFA
     KARQKLIYDV SNAYFGVLFQ REVLQAAKAA KTTFGEQLKQ ATMALSIGEG ARTDVDEAQA
     NYDQASAREI SAQNNLDSAG TAFGRLTGLG SEDLTPFNWS CMPAGVPVDA ATAEDRAADN
     LDVVSAELQV EQSKVDKLSA ASSNLPVVSF QASYGSSWSH NNRPETLGDI LLGTNSKSKS
     TMVGIGVTIP LFSGGAQLSS VREASHHYRA ALDAREDALR EARQRARVSY LGIINGLALV
     RAQEKVLSSA DSKVKSTRLG RDVGLRNSID VLNADQQYFE AVRDLADARY KYLKSHLDFD
     VALGALDKAN VDALACRPPI AE
//