Q13BC6 (MASZ_RHOPS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Malate synthase G
EC=2.3.3.9

Gene names

Name:	glcB
Ordered Locus Names:	RPD_1375

Organism

Rhodopseudomonas palustris (strain BisB5) [Complete proteome] [HAMAP]

Taxonomic identifier

316057 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length	724 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP MF_00641
Pathway	Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP MF_00641
Subunit structure	Monomer By similarity. HAMAP MF_00641
Subcellular location	Cytoplasm By similarity HAMAP MF_00641.
Sequence similarities	Belongs to the malate synthase family. GlcB subfamily.

Ontologies

Keywords
Biological process	Glyoxylate bypass Tricarboxylic acid cycle
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate cycle Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	malate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 724	724	Malate synthase G HAMAP MF_00641		PRO_1000056925
Sites
	Active site	337	1	Proton acceptor By similarity
	Active site	628	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q13BC6 [UniParc]. Last modified October 31, 2006. Version 1. Checksum: 634C61A5438BB0F0	FASTA	724	78,605
	10 20 30 40 50 60 MNRIDAHGLK IAPVLFDFIA KEAAPKTGVA PDAFWAGLAA IVRDLTPKLR KALTTRDDLQ 70 80 90 100 110 120 AKIDAWHLAN KGKKQDLAVY TAFLKEIGYL QPEPATVAVE TANVDEEIGK LCGPQLVVPL 130 140 150 160 170 180 SNARYALNAA NARWGSLYDA FYGTDAIPQE ATQAKGYDKA RGDKVIAKAK AFLDQAAPLV 190 200 210 220 230 240 AGSHSDVTAY SVIAGQFSAK LKSGNATGLK KPEQFAGYLG DAASPSAVLV VNNGLHIEIK 250 260 270 280 290 300 IDRANTIGKD DPAGVADLVI ESAVSTILDM EDSVAAVDAE DKVLIYRNVL GLMDGTLSES 310 320 330 340 350 360 FDKGGKTVTR ALNGDRTYTG PDGKDITLHG RSLLLMRNVG HHMWTDAVLD ADGAEIPEGF 370 380 390 400 410 420 LDAAVSGLIA IHDLKALGKT RNSRSGSVYI VKPKMHGPDE VALTCELFGR VEKMLGLNDN 430 440 450 460 470 480 TLKVGIMDEE RRTTVNLKAC IQNASKRIVF INTGFLDRTG DEIHTSMEAG PMIRKNEMKA 490 500 510 520 530 540 QPWIKAYEDW NVDTGLIDGL PGHAQIGKGM WAAPDKMADM LAQKIGHPQA GATTAWVPSP 550 560 570 580 590 600 TAATLHALHY HQVDVIARQQ ELQKGGPRAK LDDILTIPVS QSNWAPDDVR QEIDNNCQGI 610 620 630 640 650 660 LGYVVRWIDQ GVGCSKVPDI HDVGLMEDRA TLRISSQHLA NWLHHGVVTK EQVLESLKRM 670 680 690 700 710 720 AAVVDKQNAS DPLYRPMAPD FDGVAFEAAC DLIFKGREQP NGYTEFILHI RRREAKAAHL QDLR

References

[1]

"Complete sequence of Rhodopseudomonas palustris BisB5." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Pelletier D.A., Kyrpides N., Lykidis A., Oda Y., Harwood C.S., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BisB5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000283 Genomic DNA. Translation: ABE38613.1.
RefSeq	YP_568514.1. NC_007958.1.
3D structure databases
ProteinModelPortal	Q13BC6.
SMR	Q13BC6. Positions 2-717.
ModBase	Search...
Protein-protein interaction databases
STRING	Q13BC6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4021852.
GenomeReviews	Gene locus RPD_1375 in contig CP000283_GR.
KEGG	rpd:RPD_1375.
PATRIC	23277690. VBIRhoPal120395_1426.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2225.
HOGENOM	HBG350005.
OMA	PKMHGPD.
ProtClustDB	PRK02999.
Enzyme and pathway databases
BioCyc	RPAL316057:RPD_1375-MONOMER.
Family and domain databases
HAMAP	MF_00641. Malate_synth_G. [Tree]
InterPro	IPR011076. Malate_synth-like. IPR023310. Malate_synth_G_beta_sub_dom. IPR001465. Malate_synthase. IPR006253. Malate_synthG. [Graphical view]
Gene3D	G3DSA:2.170.170.11. Malate_synth_G_beta_sub_dom. 2 hits.
KO	K01638.
PANTHER	PTHR21631:SF1. Malate_synthase. 1 hit.
Pfam	PF01274. Malate_synthase. 1 hit. [Graphical view]
SUPFAM	SSF51645. Malat_synth_like. 1 hit.
TIGRFAMs	TIGR01345. Malate_syn_G. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MASZ_RHOPS

Accession

Primary (citable) accession number: Q13BC6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 31, 2006
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program