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Protein

Putative thymidine phosphorylase

Gene

RPD_1443

Organism
Rhodopseudomonas palustris (strain BisB5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciRPAL316057:GHDC-1466-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
Gene namesi
Ordered Locus Names:RPD_1443
OrganismiRhodopseudomonas palustris (strain BisB5)
Taxonomic identifieri316057 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
ProteomesiUP000001818: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 514514Putative thymidine phosphorylasePRO_0000314716Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi316057.RPD_1443.

Structurei

3D structure databases

ProteinModelPortaliQ13B59.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiMAVLGNE.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q13B59-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNASHLSRPP LTIRRISLDT GRENVAVISR RSRALRADVF RGFSRVALRI
60 70 80 90 100
NTKVLLATLM ITDDDAMIGP DELGLSEPAF RRFNEPVGSA VSVSPAQPPA
110 120 130 140 150
SLDAVRAKIQ GHTLTPAEIT AVIDDVAHFR YSDMEIAAFL ISAARFTSTD
160 170 180 190 200
ELLALVDAMA SVGTRLKWQN PIVVDKHCIG GIPGNRTTMI VVPIVAAQGL
210 220 230 240 250
MIPKTSSRAI TSPAGTADTM EVLARVDLDV EQMKRVVTTC GGCLIWGGHV
260 270 280 290 300
NLSPADDILI SVERPLSLDT PEQMVASIMS KKLAAGSTRL LIDFPVGPSA
310 320 330 340 350
KIASASEAMR LRKLFEFVGD HFGIAVEVVT TDGRQPIGRG IGPVLEARDV
360 370 380 390 400
MAVLGNEPNA PADLREKSLR LAAHLLEYDP LLRGGAGYAR AKELLDSGAA
410 420 430 440 450
LKKMQQIIDA QGPSVCNSEL GSHAADVLAP ADGVVNGIDC LRINRLARTA
460 470 480 490 500
GAPIVKGAGI DLFKKIGDRV DQGEPIYRIY ASDRSELDLA IAAAEAESGF
510
SVNHHSPAAV EPVS
Length:514
Mass (Da):54,666
Last modified:October 31, 2006 - v1
Checksum:i1253EE274B903BB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000283 Genomic DNA. Translation: ABE38680.1.
RefSeqiYP_568581.1. NC_007958.1.

Genome annotation databases

EnsemblBacteriaiABE38680; ABE38680; RPD_1443.
GeneIDi4021920.
KEGGirpd:RPD_1443.
PATRICi23277829. VBIRhoPal120395_1495.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000283 Genomic DNA. Translation: ABE38680.1.
RefSeqiYP_568581.1. NC_007958.1.

3D structure databases

ProteinModelPortaliQ13B59.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316057.RPD_1443.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE38680; ABE38680; RPD_1443.
GeneIDi4021920.
KEGGirpd:RPD_1443.
PATRICi23277829. VBIRhoPal120395_1495.

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiMAVLGNE.
OrthoDBiEOG61ZTGG.

Enzyme and pathway databases

BioCyciRPAL316057:GHDC-1466-MONOMER.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BisB5.

Entry informationi

Entry nameiTYPH_RHOPS
AccessioniPrimary (citable) accession number: Q13B59
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 31, 2006
Last modified: February 4, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.