ID   DNAE2_RHOPS             Reviewed;        1110 AA.
AC   Q139V1;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   16-JUN-2009, entry version 18.
DE   RecName: Full=Error-prone DNA polymerase;
DE            EC=2.7.7.7;
GN   Name=dnaE2; OrderedLocusNames=RPD_1903;
OS   Rhodopseudomonas palustris (strain BisB5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Pelletier D.A., Kyrpides N.,
RA   Lykidis A., Oda Y., Harwood C.S., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris BisB5.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA polymerase involved in damage-induced mutagenesis
CC       and translesion synthesis (TLS). It is not the major replicative
CC       DNA polymerase (By similarity).
CC   -!- CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) =
CC       diphosphate + DNA(n+1).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-C family. DnaE2
CC       subfamily.
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DR   EMBL; CP000283; ABE39138.1; -; Genomic_DNA.
DR   RefSeq; YP_569039.1; -.
DR   GeneID; 4022385; -.
DR   GenomeReviews; CP000283_GR; RPD_1903.
DR   KEGG; rpd:RPD_1903; -.
DR   HOGENOM; Q139V1; -.
DR   OMA; Q139V1; MGFYSPD.
DR   BioCyc; RPAL316057:RPD_1903-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:HAMAP.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0045020; P:error-prone DNA repair; IEA:HAMAP.
DR   HAMAP; MF_01902; -; 1.
DR   InterPro; IPR011708; DNA_pol3_alpha.
DR   InterPro; IPR004365; NA_bd_OB_tRNA-helicase.
DR   InterPro; IPR004013; PHP_C.
DR   InterPro; IPR003141; PHP_N.
DR   InterPro; IPR004805; PolC_alpha.
DR   Pfam; PF07733; DNA_pol3_alpha; 1.
DR   Pfam; PF02811; PHP; 1.
DR   Pfam; PF01336; tRNA_anti; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   TIGRFAMs; TIGR00594; polc; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase.
FT   CHAIN         1   1110       Error-prone DNA polymerase.
FT                                /FTId=PRO_1000070597.
SQ   SEQUENCE   1110 AA;  123650 MW;  CC1D06567E5E3390 CRC64;
     MKVPAYAEIG VTTNFSFLEG GSHPQDYVHE ASRLGLEAIG IADRNTLAGV VRAYSELGNE
     DLIHKPRLLI GARLVFADGT PDVLAYPVDR AAYGRLCRLL SVGKLRGAKG ECHLAVADLE
     AFSQGLSLVL MPPYRFQASA IAAALQRLTA LESGGVWLGL TPYYRGDDKR RLARLKRVAW
     AARVPGIATN DVLYHHPERR ALQDVLSCVR EKTTIDKIGR RLEANAERHL KPAAEMARLF
     RADPDAIAET LRFAAGISFT LDELKYHYPD EPVPPGKTAQ QHLEDLTWEG VAEYFPAGIS
     DKLHATIDKE LGIIAHRGYA QYFLTVHDIV RYARSQDILC QGRGSAANSA VCYVLGITCV
     DPTEIDLLFE RFVSEERDEP PDIDVDFEHS RREEVMQYIY RRYGRHRAAI VATVIHYRPR
     SAIRDVGKAL GLSEDVTAAL ADTVWGSWGK GLNEMQVKQA GLDPHNPLIG RAVELATELI
     GFPRHLSQHV GGYVLTQDRL DSYVPIGNAA MEGRTFIEWD KDDIDAIKMM KVDVLALGML
     TCIRKGFDLI AQHKGVRYAL SDIKSEDDNA VYQMLQRGES IGVFQVESRA QMNMLPRLKP
     KCFYDLVIEV AIVRPGPIQG DMVHPYLRRR NKQEPVVYPA PAGHAGDANE LEVILGKTLG
     VPLFQEQAMR IAIEAAHFTP DEANQLRRAM ATFRNVGTIG KFESKMVGNL VARGYDPVFA
     KNCFEQIKGF GSYGFPESHA ASFAKLVYVS AWMKCEHPDA FCCALLNSQP MGFYAPAQIV
     GDARANEVEV RPVDVSFSDG QCTLEERCGK HHAVRLGFRQ IDGFVWADPD EERVRREAGL
     LPSEDWAARI VAARARGPFN SLERFARLTA LPKRALILLA DADAFRSLGL DRRAALWAVR
     RLPDDVPLPL FEAASASEQL DENAAPLPQM PTAEHVVADY QTVRLSLKGH PMEFLRPLFA
     AERVVTCRSI SESRVSGQRM RCAGVVLVRQ RPGSAKGVVF ITLEDETGIA NLVVWPAVME
     TFRKEVMGAR LLWVEGRIQA SPEGVVHLVA ERLSDRSFEM TRLSDNLAAP RLGELHEPLN
     DDRREHPDNP AQRIRHPRDV RILPPSRDFH
//