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Protein

Pyrroloquinoline-quinone synthase

Gene

pqqC

Organism
Rhodopseudomonas palustris (strain BisB5)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.UniRule annotation

Catalytic activityi

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. pyrroloquinoline-quinone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. pyrroloquinoline quinone biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

PQQ biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciRPAL316057:GHDC-2059-MONOMER.
UniPathwayiUPA00539.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrroloquinoline-quinone synthaseUniRule annotation (EC:1.3.3.11UniRule annotation)
Alternative name(s):
Coenzyme PQQ synthesis protein CUniRule annotation
Pyrroloquinoline quinone biosynthesis protein CUniRule annotation
Gene namesi
Name:pqqCUniRule annotation
Ordered Locus Names:RPD_2031Imported
OrganismiRhodopseudomonas palustris (strain BisB5)Imported
Taxonomic identifieri316057 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
ProteomesiUP000001818: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi316057.RPD_2031.

Structurei

3D structure databases

ProteinModelPortaliQ139H3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PqqC family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5424.
HOGENOMiHOG000217947.
KOiK06137.
OMAiFRDRATR.
OrthoDBiEOG6JTC7S.

Family and domain databases

Gene3Di1.20.910.10. 1 hit.
HAMAPiMF_00654. PQQ_syn_PqqC.
InterProiIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. Thiaminase-2/PQQC.
[Graphical view]
PfamiPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMiSSF48613. SSF48613. 1 hit.
TIGRFAMsiTIGR02111. PQQ_syn_pqqC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q139H3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAFSINGAA SLRSADELEA ALRQIGAARY HNLHPFHRLL HGGQLTKGQV
60 70 80 90 100
QAWALNRYYY QSTIPIKDAV VISRFRDRAT RVEWRHRIED HDGDIGSEGG
110 120 130 140 150
IERWLKLTEG LGLDSAYVES TEGILPATRF AVDAYVHFVR DRTPLEAIAS
160 170 180 190 200
SLTELFAPNL HEERISGMLA HYDFVNPEIM SYFKRRLAQA PRDADFALDY
210 220 230 240 250
VKRHAATPAE REAVCNALIF KTNVLWAQLD ALHHAYVDGH IPPGAFVPQA

G
Length:251
Mass (Da):28,201
Last modified:October 31, 2006 - v1
Checksum:i97C9F01531BA207A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000283 Genomic DNA. Translation: ABE39266.1.
RefSeqiWP_011502450.1. NC_007958.1.
YP_569167.1. NC_007958.1.

Genome annotation databases

EnsemblBacteriaiABE39266; ABE39266; RPD_2031.
GeneIDi4022513.
KEGGirpd:RPD_2031.
PATRICi23279039. VBIRhoPal120395_2097.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000283 Genomic DNA. Translation: ABE39266.1.
RefSeqiWP_011502450.1. NC_007958.1.
YP_569167.1. NC_007958.1.

3D structure databases

ProteinModelPortaliQ139H3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316057.RPD_2031.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE39266; ABE39266; RPD_2031.
GeneIDi4022513.
KEGGirpd:RPD_2031.
PATRICi23279039. VBIRhoPal120395_2097.

Phylogenomic databases

eggNOGiCOG5424.
HOGENOMiHOG000217947.
KOiK06137.
OMAiFRDRATR.
OrthoDBiEOG6JTC7S.

Enzyme and pathway databases

UniPathwayiUPA00539.
BioCyciRPAL316057:GHDC-2059-MONOMER.

Family and domain databases

Gene3Di1.20.910.10. 1 hit.
HAMAPiMF_00654. PQQ_syn_PqqC.
InterProiIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. Thiaminase-2/PQQC.
[Graphical view]
PfamiPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMiSSF48613. SSF48613. 1 hit.
TIGRFAMsiTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BisB5Imported.

Entry informationi

Entry nameiQ139H3_RHOPS
AccessioniPrimary (citable) accession number: Q139H3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 31, 2006
Last sequence update: October 31, 2006
Last modified: February 4, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.