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Protein
Submitted name:

CD4 protein

Gene

CD4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
CD4 proteinImported
Submitted name:
CD4 receptorImported
Gene namesi
Name:CD4Imported
Synonyms:CD4 receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 7146Sequence analysisPRO_5004182022Add
BLAST

Proteomic databases

PaxDbiQ13969.
PRIDEiQ13969.

Expressioni

Gene expression databases

BgeeiQ13969.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000011653.

Chemistry

BindingDBiQ13969.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 7152Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IK9F. Eukaryota.
ENOG410YWI4. LUCA.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR000973. CD4.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013151. Immunoglobulin.
[Graphical view]
PANTHERiPTHR11422:SF0. PTHR11422:SF0. 1 hit.
PfamiPF00047. ig. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q13969-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRGVPFRHL LLVLQLALLP AATQGKKVVL GKKGDTVELT CTASQKKSIQ
60 70
FHWKNSNQIK ILGNQGSFLT K
Length:71
Mass (Da):7,844
Last modified:January 1, 1999 - v2
Checksum:iA5C9D84816135C86
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei71 – 711Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S79267 mRNA. Translation: AAB35273.1.
X87579 Genomic DNA. Translation: CAA60883.1.
PIRiI60082.
UniGeneiHs.631659.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S79267 mRNA. Translation: AAB35273.1.
X87579 Genomic DNA. Translation: CAA60883.1.
PIRiI60082.
UniGeneiHs.631659.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000011653.

Chemistry

BindingDBiQ13969.

Proteomic databases

PaxDbiQ13969.
PRIDEiQ13969.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IK9F. Eukaryota.
ENOG410YWI4. LUCA.

Miscellaneous databases

ChiTaRSiCD4. human.

Gene expression databases

BgeeiQ13969.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR000973. CD4.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013151. Immunoglobulin.
[Graphical view]
PANTHERiPTHR11422:SF0. PTHR11422:SF0. 1 hit.
PfamiPF00047. ig. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Splice-mediated insertion of antisence and sence Alu repeats in human CD4 gene: identification of three exons of CD4 mRNA."
    Zverev V.V., Blinov V.M., Nedospasov S.A.
    Submitted (APR-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Nucleotide sequence of two exons of the human T-lymphocyte CD4 receptor gene."
    Zverev V.V., Sidorov A.V., Nedospasov S.A., Maliushova V.V., Udalova I.A., Andzhaparizde O.G., Blinov V.M.
    Vopr. Virusol. 40:100-102(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ13969_HUMAN
AccessioniPrimary (citable) accession number: Q13969
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: January 1, 1999
Last modified: April 13, 2016
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.