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Protein
Submitted name:

CD4 protein

Gene

CD4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
CD4 proteinImported
Submitted name:
CD4 receptorImported
Gene namesi
Name:CD4Imported
Synonyms:CD4 receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 7146Sequence analysisPRO_5007699156Add
BLAST

Proteomic databases

PeptideAtlasiQ13969.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000011653.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 7152Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IK9F. Eukaryota.
ENOG410YWI4. LUCA.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR000973. CD4.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013151. Immunoglobulin.
[Graphical view]
PANTHERiPTHR11422:SF0. PTHR11422:SF0. 1 hit.
PfamiPF00047. ig. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q13969-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRGVPFRHL LLVLQLALLP AATQGKKVVL GKKGDTVELT CTASQKKSIQ
60 70
FHWKNSNQIK ILGNQGSFLT K
Length:71
Mass (Da):7,844
Last modified:January 1, 1999 - v2
Checksum:iA5C9D84816135C86
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei71 – 711Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S79267 mRNA. Translation: AAB35273.1.
X87579 Genomic DNA. Translation: CAA60883.1.
PIRiI60082.
UniGeneiHs.631659.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S79267 mRNA. Translation: AAB35273.1.
X87579 Genomic DNA. Translation: CAA60883.1.
PIRiI60082.
UniGeneiHs.631659.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000011653.

Proteomic databases

PeptideAtlasiQ13969.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IK9F. Eukaryota.
ENOG410YWI4. LUCA.

Miscellaneous databases

ChiTaRSiCD4. human.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR000973. CD4.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013151. Immunoglobulin.
[Graphical view]
PANTHERiPTHR11422:SF0. PTHR11422:SF0. 1 hit.
PfamiPF00047. ig. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Splice-mediated insertion of antisence and sence Alu repeats in human CD4 gene: identification of three exons of CD4 mRNA."
    Zverev V.V., Blinov V.M., Nedospasov S.A.
    Submitted (APR-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Nucleotide sequence of two exons of the human T-lymphocyte CD4 receptor gene."
    Zverev V.V., Sidorov A.V., Nedospasov S.A., Maliushova V.V., Udalova I.A., Andzhaparizde O.G., Blinov V.M.
    Vopr. Virusol. 40:100-102(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ13969_HUMAN
AccessioniPrimary (citable) accession number: Q13969
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: January 1, 1999
Last modified: July 6, 2016
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.